Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$150K - $180K *
Shape the future of billing operations by leading a team to enhance accuracy, timeliness, and efficiency. Drive process improvements, manage complex accounts, and collaborate across functions to resol...
1 week ago
Manager, Customer Success Engineering
$124K - $210K *
Drive customer success by leading a team of engineers to enhance GitLab adoption, develop scalable enablement programs, and collaborate with cross-functional teams to achieve measurable business outco...
2 weeks ago
$110K - $130K *
Shape the future of client solutions by leveraging your technical expertise and business acumen. Collaborate with sales teams to design tailored solutions, deliver compelling presentations, and drive...
3 weeks ago
$110K - $130K *
Join a team that's transforming healthcare by driving enterprise sales. Own your territory, build relationships with key stakeholders, and close complex deals while expanding existing accounts. Your e...
1 week ago
Principal Solutions Executive II - Security
$160K - $192K *
Accelerate revenue growth by driving security services sales, managing the full sales lifecycle, and building strategic relationships with clients and partners to enhance market presence and deliver i...
2 weeks ago
Sr. Systems Engineer - Mainframe API Services
$105K - $124K *
Join a team that's driving mainframe API modernization and reliability. Leverage your expertise in IBM z/OS Connect, REST APIs, and automation to enhance system performance and security in a dynamic I...
Reposted yesterday
$110K - $130K *
Innovate healthcare delivery by developing AI solutions that enhance operations and resident experiences. Collaborate with teams to automate processes and improve clinical decision-making in senior ca...
4 weeks ago
Senior Account Executive, High Tech End User
$132K - $170K *
Transform client relationships and drive growth by consulting with C-level executives to implement strategic solutions that enhance value and satisfaction across major accounts, ensuring retention and...
5 days ago
$100K - $120K *
Transform the internal IT landscape by managing employee support, systems administration, and infrastructure scalability. Drive automation and security initiatives while enhancing user experience in a...
5 days ago
Senior Structural Engineer-Bridge
$88K - $154K *
Join a team that's redefining bridge engineering by delivering innovative designs and solutions. Collaborate on diverse projects, ensuring structural reliability and efficiency while enhancing your ex...
1 week ago
Director, Business Systems & Solution Architecture (D365 F&O)
$155K - $170K *
Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...
Reposted today
Senior Implementation Consultant (Intacct)
$100K - $115K *
Partner with us to lead complex Sage Intacct implementations, guiding clients through analysis, design, and optimization. Leverage your expertise to enhance client relationships and drive successful p...
3 weeks ago
Director of SEC Reporting and Technical Accounting
$170K - $210K *
Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...
1 week ago
$120K - $145K *
Champion the management of mainframe outsourcing, ensuring optimal performance and vendor accountability while providing technical leadership and support for mainframe technologies across the organiza...
2 weeks ago
$80K - $95K *
Lead the charge in delivering innovative engineering solutions for diverse projects. Collaborate with teams to ensure design accuracy, mentor junior staff, and drive project success while adhering to...
6 days ago
Senior Engineer (Engineering & Construction) - Data Center
$110K - $130K *
Optimize complex mechanical and electrical systems for data centers, ensuring high availability and reliability. Lead design, engineering, and project management activities while collaborating with mu...
2 weeks ago
$63K - $129K *
Contribute to system quality by executing test cases, analyzing requirements, and validating functionality to ensure compliance and stability in a fast-paced environment. Collaborate with teams to enh...
Reposted 2 weeks ago
$80K - $95K *
Unlock potential by managing technology alignment for diverse clients. Collaborate with stakeholders to ensure optimal tech solutions, maintain client environments, and drive innovation through strate...
3 weeks ago
$80K - $95K *
Lead technology alignment initiatives for diverse clients, ensuring optimal support for their business objectives. Collaborate with stakeholders, perform on-site visits, and streamline processes throu...
3 weeks ago
Senior Manager, Web Optimization & Search Strategy
$120K - $145K *
Drive website optimization and search strategy initiatives, enhancing digital visibility and engagement. Collaborate with cross-functional teams to implement SEO, GEO, and technical strategies that el...
6 days ago
$110K - $130K *
Join a dynamic team to enhance system reliability and performance through automation, ensuring minimal downtime and optimal user experience while driving continuous improvements in a cutting-edge tech...
1 week ago
$165K - $220K *
Pioneer innovative solutions by collaborating with defense clients to operationalize real-time intelligence. Design and deploy data pipelines and applications on Palantir Foundry, ensuring mission-cri...
4 weeks ago
Project Controls Lead - Data Center Construction
$160K - $190K *
Champion project control excellence by developing strategies, collaborating with teams, and optimizing performance to ensure successful project delivery within timelines and budgets. Lead initiatives...
2 weeks ago
$110K - $130K *
Drive operational excellence by enhancing system reliability and automation. Collaborate with teams to minimize downtime, optimize performance, and implement innovative solutions that ensure high avai...
1 week ago
Vice President, Capital & Investments (Real Estate)
$200K - $300K *
Elevate your career by leading investment strategies and capital allocation for a dynamic enterprise. Collaborate with senior leadership to drive portfolio performance and ensure alignment with long-t...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.