Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$155K - $226K *

Elevate Cisco's CX partner strategy by collaborating with leaders to enhance global growth through innovative observability solutions and technical guidance, ensuring successful partner implementation...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$95K - $115K *

Elevate client experiences by leading Microsoft 365 Modern Work solutions, leveraging deep technical expertise to solve complex business challenges and drive innovation in collaboration systems...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$170K - $185K *

Champion innovative software solutions by leading complex projects, mentoring engineers, and driving technical excellence across teams. Collaborate on strategic initiatives to enhance reliability and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $137K *

Lead the charge in transforming workflows with AI, driving adoption and measurable impact in legal, tax, and trade sectors. Collaborate with clients and teams to design, implement, and evaluate innova...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$95K - $115K *

Unlock potential by ensuring the stability and efficiency of in-house IT systems. Mentor junior staff, manage system design and maintenance, and provide expert support across various technologies whil...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $130K *

Champion quality and commissioning excellence across diverse construction projects, ensuring compliance and safety while fostering collaboration among teams and stakeholders to drive impactful results...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$250K - $300K *

Lead the charge in driving enterprise sales by collaborating with Microsoft teams to identify and capitalize on AVD opportunities. Leverage your expertise in VDI and EUC technologies to foster relatio...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Strategize and lead global solution marketing initiatives to enhance customer engagement and drive growth in the data center and smart building sectors, collaborating closely with product management a...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Drive innovative electrical engineering solutions for complex industrial projects. Lead multidisciplinary teams from concept to construction, ensuring quality and client satisfaction while fostering b...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$88K - $105K *

Engage in comprehensive finance integration for acquired companies, ensuring accurate data mapping, system conversion, and post-close stabilization. Collaborate with cross-functional teams to streamli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $189K *

Lead, shape, and execute advanced penetration testing assessments, overseeing scoping, planning, and reporting. Collaborate with teams to enhance cybersecurity measures across various platforms, ensur...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Lead comprehensive program controls initiatives, ensuring efficient budget management, scheduling, and performance reporting for multiple complex projects. Collaborate with stakeholders to optimize pr...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $132K *

Help us drive growth as a strategic Channel Account Manager, collaborating with partners to create scalable sales strategies, enhance engagement, and achieve measurable outcomes in the enterprise tech...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in advancing AI applications in healthcare by developing intelligent agents that uncover financial opportunities within complex datasets, transforming manual analyses into scalable wor...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$75K - $107K *

Elevate customer relationships and drive revenue growth by managing complex Federal accounts. Collaborate with cross-functional teams to align strategies with customer needs, ensuring retention and ex...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$63K - $129K *

Shape your career by driving Agile execution excellence in federal HCM modernization. Lead cross-functional teams, facilitate SAFe ceremonies, and foster a continuous improvement culture within a larg...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$87K - $157K *

Lead the charge in designing and reviewing structural components for substation and transmission projects, ensuring quality control and mentoring junior engineers while engaging with clients and suppo...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Technical Services

$120K - $145K *

Join a dynamic team to drive technical success and adoption across enterprise accounts. Leverage your expertise in project management and technical execution to enhance deployment health and fuel acco...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Drive innovation by developing scalable data pipelines and analytics solutions. Collaborate with teams to translate complex business problems into actionable insights across diverse domains, ensuring...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate your career by managing cultural resource projects, leading field teams, and ensuring compliance with regulations. Collaborate with experts to deliver impactful results across the Midwest and...

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$80K - $95K *

Unlock your potential as a Senior Archaeologist, managing cultural resource projects and leading field teams. Collaborate across regions to deliver impactful results while ensuring compliance with reg...

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$75K - $158K *

Join a dynamic team to enhance cybersecurity by analyzing threats, developing intelligence reports, and collaborating with stakeholders to protect critical assets and improve incident response capabil...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in developing and managing global benefits programs that enhance employee well-being and support business objectives. Collaborate with stakeholders to ensure compliance, optimize benef...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Explore your career by building strategic partnerships in the life sciences sector. Drive account growth, develop client relationships, and connect with key stakeholders to enhance business opportunit...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$100K - $130K *

Drive the design and deployment of secure AI applications in cloud environments, integrating advanced technologies like machine learning and ServiceNow solutions to enhance operational efficiency and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.