Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$120K - $145K *

Drive innovative solutions by architecting complex enterprise technologies for federal healthcare, focusing on VA and other agencies. Collaborate across teams to translate requirements into scalable...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $180K *

Innovate with us as you lead technical delivery for enterprise data integration and migration projects, focusing on Higher Education and Salesforce ecosystems. Drive solution architecture, manage team...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Inspire growth by leading strategic initiatives for key telecom accounts, fostering executive relationships, and driving multi-year revenue plans. Collaborate across teams to align solutions with evol...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$88K - $105K *

Drive project success by leading self-perform scopes from preconstruction to closeout. Collaborate with teams to ensure quality, safety, and productivity while managing budgets and schedules for optim...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$140K - $160K *

Drive the development of critical enterprise applications for DoD personnel, enhancing program and financial management capabilities. Collaborate within a product team to modernize technology and deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $383K *

Join a team that's redefining internal audit excellence. Lead strategic initiatives, enhance risk management, and drive compliance while leveraging cutting-edge technologies to optimize processes and...

United StatesRemote

Today

  •   15+ years exp.  •   Real Estate & Construction

$148K - $256K *

Shape the future of data engineering by architecting scalable, cloud-native data platforms on Azure and Databricks. Influence the organization’s data practices to leverage AI-driven insights, driving...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$147K - $275K *

Drive data-driven strategies by analyzing complex datasets and providing actionable insights. Collaborate with cross-functional teams to enhance decision-making processes and optimize business perform...

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $160K *

Unlock potential by designing and maintaining innovative solutions on the Nuvolo platform, ensuring seamless integration and optimal performance while collaborating with cross-functional teams to meet...

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$132K - $176K *

Drive market growth by developing strategic partnerships and solutions. Collaborate with teams to enhance customer engagement and competitive positioning, ensuring alignment with long-term objectives...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$75K - $158K *

Join a team that's dedicated to optimizing operations in a fast-paced environment. Support technical and functional stakeholders while ensuring seamless processing and troubleshooting across systems...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to optimizing software systems and applications. Leverage your expertise in application administration to enhance performance, ensure security, and support users across mu...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$163K - $203K *

Elevate security standards by leading classified design and accreditation for defense facilities. Collaborate with cross-functional teams to ensure compliance and streamline processes for rapid deploy...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $110K *

Engage with clients, driving success in digital campaign execution. Become an expert in programmatic advertising processes, enhancing customer satisfaction through effective communication and collabor...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $175K *

Shape the cloud infrastructure landscape by ensuring security, scalability, and efficiency. Collaborate with engineers to build resilient systems and drive best practices, enabling smooth deployment a...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $111K *

Take ownership of Oracle EBS Project Accounting operations, enhancing project costing, billing, and financial processes. Collaborate with diverse teams to document workflows and improve operational re...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$90K - $120K *

Optimize operational excellence in healthcare IT by managing production support, driving issue resolution, and ensuring timely reporting for customer-facing technology delivery...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $171K *

Join a team that's focused on leading software development initiatives while mentoring talent. You'll guide a skilled group in building modern web applications, leveraging AI tools, and enhancing proj...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$114K - $171K *

Join a dynamic team as a technical leader, guiding software development while mentoring talent. Drive innovation in web applications using modern frameworks, enhance team performance, and collaborate...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$124K - $187K *

Shape your career by leading the design and operation of AI and ML systems. Collaborate across teams to establish architecture standards, optimize workflows, and ensure operational readiness for innov...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$70K - $121K *

Lead a dynamic team in the installation and commissioning of fire/life safety systems. Drive project success through technical expertise, mentorship, and effective communication, ensuring customer sat...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$120K *

Lead the charge in securing AI applications by building robust defenses and controls across our core security platforms. This hands-on role involves engineering, deploying, and operating security meas...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Empower our cybersecurity initiatives by providing strategic leadership and ensuring compliance with DoD standards. Drive enterprise-level security architecture and risk management across multiple Tas...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$138K - $173K *

Drive cross-functional collaboration to ensure high-quality software delivery. Lead and mentor a team of engineers while optimizing processes and fostering a culture of innovation and continuous impro...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $180K *

Grow enterprise SAP relationships by managing key accounts and driving new business. Leverage your expertise to expand client portfolios, develop strategic plans, and ensure client satisfaction while...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.