Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$130K - $165K *
Transform the defined benefit landscape by driving growth for ProAdmin. Build strategic partnerships and engage directly with plan sponsors to enhance confidence in benefit calculations and streamline...
Yesterday
Databricks Solution Architect (Data & AI)
$145K - $175K *
Innovate by designing and delivering advanced data and AI platforms on Databricks. Collaborate with clients and teams to shape solutions, optimize architectures, and drive successful implementations f...
2 weeks ago
Sr. DataOps Engineer, Data Platform
$130K - $160K *
Transform data operations by leading our Snowflake platform migration, ensuring security, reliability, and cost efficiency while collaborating across teams to standardize practices and enhance data ma...
1 week ago
Junior Solutions Architect / Architecte de solutions junior
$88K - $113K *
Engage with sales and product teams to deliver technical solutions, ensuring customer satisfaction through effective communication and collaboration. Identify technical issues and provide guidance thr...
Reposted yesterday
Principal AI Research Cybersecurity Scientist (Bay Area)
$175K - $210K *
Innovate in AI research by driving cutting-edge projects in cybersecurity. Leverage your expertise in LLMs and model evaluation to translate complex challenges into actionable insights, collaborating...
2 weeks ago
Oracle Cloud ERP Solution Architect
$120K - $145K *
Drive comprehensive Oracle Cloud ERP solutions by architecting client strategies, managing cross-functional teams, and ensuring alignment with business goals. Lead project delivery, stakeholder engage...
Today
$110K - $130K *
Lead the design and engineering of electrical systems for complex building projects, ensuring compliance with codes and standards while collaborating with multidisciplinary teams to deliver high-quali...
1 week ago
Advanced Weapons Business Process Leader
$139K - $208K *
Join a team that's transforming Global Supply Chain and ERP processes. As a Staff Business Process Leader, you'll drive process standardization, support ERP transformations, and engage with stakeholde...
2 weeks ago
$75K - $95K *
Join a team that's driving innovation in mobile advertising by managing fraud mitigation and partner relationships. Leverage your expertise in advertising measurement to navigate the dynamic landscape...
4 days ago
$80K - $95K *
Drive strategic program management for enterprise accounts, overseeing complex initiatives and fostering client relationships. Collaborate cross-functionally to enhance processes, ensure client satisf...
1 week ago
$94K - $266K *
Champion MuleSoft implementations by developing clean code and guiding teams. Leverage expertise in Salesforce and API management to deliver enterprise-grade solutions while mentoring junior developer...
4 weeks ago
$100K - $140K *
Lead operational procurement for network infrastructure and data-center projects. Collaborate with cross-functional teams to source suppliers, negotiate contracts, and ensure compliance with procureme...
4 days ago
$80K - $95K *
Lead comprehensive evaluations of federally subsidized housing, ensuring compliance with safety and accessibility standards. Collaborate with inspectors to enhance operational performance and resolve...
3 days ago
$160K - $200K *
Join a team that's redefining cloud operations by leading a unified infrastructure organization. Drive platform reliability, cost efficiency, and operational excellence while collaborating with cross...
Today
Member of Technical Staff, Forward Deployed Engineer (New Stealth Startup)
$150K - $300K *
Transform enterprise operations by developing AI solutions tailored to customer needs. Engage directly with clients, manage the full technical lifecycle, and drive measurable improvements in AI perfor...
1 week ago
$73K - $212K *
Lead innovative AI solutions as a Manager in Data and Analytics Engineering. Supervise teams, manage client accounts, and drive exceptional results while fostering relationships and embracing technolo...
2 weeks ago
Contracts Manager (Procurement)
$120K - $180K *
Optimize procurement processes and vendor relationships, ensuring effective contract management and risk mitigation in a dynamic technology environment. Collaborate with cross-functional teams to secu...
Yesterday
Director of Integration & Operational Excellence
$150K - $175K *
Lead the charge in integrating acquisitions by developing operational capabilities, ensuring seamless transitions, and driving performance improvements across multiple functions to enhance customer re...
Today
Senior Middleware Administrator
$110K - $130K *
Lead the charge in optimizing enterprise middleware platforms through effective administration, automation, and security management, ensuring high availability and compliance while enhancing operation...
3 weeks ago
$160K - $280K *
Join us to architect and build a cutting-edge web platform, driving marketing innovation through AI agents. Own technical decisions, enhance user experiences, and ensure seamless integration with our...
3 weeks ago
$110K - $130K *
Transform clients' digital strategies by leading pre-sales initiatives. Engage, inspire, and coach stakeholders through innovative solutions, ensuring alignment with business goals and implementing At...
Reposted 3 weeks ago
$100K - $120K *
Advance payer integrations by managing complex processes and relationships. Drive outreach and research to establish direct connectivity with 3,000+ payers, ensuring accurate data and efficient handof...
6 days ago
Technical Integration Consultant, Sr. Associate
$77K - $202K *
Unlock potential as you guide clients in optimizing business applications through integration analysis, implementation, and support, while mentoring junior team members and enhancing your technical ex...
1 week ago
Senior Azure Virtual Desktop Engineer
$121K - $182K *
Lead the charge in designing and optimizing secure Azure Virtual Desktop environments. Collaborate with cross-functional teams to ensure high availability and performance, delivering top-quality solut...
Reposted today
$112K - $179K *
Join a dynamic team to lead security engineering initiatives, ensuring robust protection of cloud infrastructure and sensitive data while driving compliance and mission success in complex federal envi...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.