Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$260K *

Join a team that's driving digital transformation by managing client accounts, developing strategies, and delivering innovative technology solutions. Build long-term relationships while collaborating...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $120K *

Join a dynamic team to lead and enhance information security programs, ensuring compliance and risk management across diverse industries. Collaborate with executives to develop strategies that protect...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$123K - $166K *

Join a team that's dedicated to enhancing cloud platform reliability and security. As a Platform Engineer, you'll leverage your expertise in Kubernetes and CI/CD to build and maintain robust infrastru...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Shape the future of systems administration by managing upgrades, troubleshooting, and ensuring security compliance across Linux and Windows environments. Collaborate on cloud architecture and maintain...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$98K - $164K *

Explore innovative technical architectures and solutions in energy management. Collaborate with teams to deliver digital substations and automation systems while engaging with customers from design to...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Shape the future of product design by transforming concepts into high-fidelity experiences. Collaborate with cross-functional teams to enhance user interactions through innovative prototyping and AI-a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $133K *

Lead the charge in delivering innovative full-stack solutions, collaborating with diverse teams to modernize applications on AWS using cutting-edge technologies, ensuring operational resilience and me...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $133K *

Champion innovative solutions by collaborating with cross-functional teams to develop scalable, cloud-native applications. Leverage your full-stack expertise to modernize systems and deliver high-valu...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$94K - $107K *

Transform data governance operations by driving process adoption, supporting data stewards, and enhancing governance tools. Collaborate with teams to ensure compliance, improve workflows, and leverage...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $200K *

Advance backend solutions and frontend features, collaborating across teams to build scalable systems and AI integrations, driving product growth from conception to execution...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$232K - $320K *

Empower your career by providing expert guidance in AI security solutions. Lead technical validations, influence product roadmaps, and architect comprehensive security strategies to protect AI applica...

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$98K - $206K *

Join a dynamic team as a Senior CSfC Systems Engineer, deploying cutting-edge networking solutions across the U.S. and globally. Leverage your expertise in virtualization and data center architecture...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$240K *

Lead enterprise cybersecurity and infrastructure initiatives, advising executive leadership on risk management and technology investments. Shape policies and governance to ensure a secure, resilient t...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$150K - $160K *

Drive revenue growth by identifying and developing federal and B2B opportunities in cybersecurity. Own the business development lifecycle, build strategic partnerships, and leverage compliance experti...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$170K - $325K *

Elevate your career by securing and managing the transition to a hybrid-cloud infrastructure. Own identity management, cloud security, and developer tooling while leading incident response and threat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$187K - $220K *

Unlock potential by designing and building AI-powered solutions to enhance enterprise IT operations, collaborating directly with customers and driving impactful product features across backend and aut...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Explore a leadership role for large-scale projects, driving success through effective planning, risk management, and client relations while ensuring safety and financial performance throughout the pro...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$156K - $239K *

Lead the charge in deploying and optimizing enterprise ArcGIS environments, managing complex migrations, and troubleshooting infrastructure issues while mentoring engineers and advising on technical d...

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$122K - $183K *

Elevate user growth and monetization through thoughtful design and experimentation, collaborating closely with cross-functional teams to enhance onboarding and product engagement while maintaining hig...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $158K *

Shape the future of federal data integration by leveraging Oracle EBS expertise to create actionable insights and advanced dashboards. Collaborate with cross-functional teams and enhance government da...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$204K - $216K *

Unlock potential by designing robust data models that empower AI systems. You will ensure data coherence and quality, bridging knowledge representation and machine learning across diverse communities...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's shaping the future of interconnect technology by designing innovative connector solutions. Leverage your engineering expertise to collaborate globally and meet the demands of leadin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K *

Drive enterprise-level implementations of phishing-resistant authentication solutions, leading technical deployments and integrations across various identity platforms while ensuring customer success...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$134K - $197K *

The Senior Sales Engineer at Obsidian Security will drive and manage the technical evaluation stage of the sales process while mentoring the team. This role requires expertise in SaaS security challen...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $126K *

Elevate AI capabilities by building and maintaining governed solutions. Collaborate cross-functionally to translate business needs into technical designs, ensuring ethical AI use and robust integratio...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.