Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Lead Information Security Engineer
$139K - $250K *
Shape the future of cybersecurity by designing secure architectures and leading initiatives to protect systems and infrastructure. Drive improvements in security posture while collaborating with teams...
1 month ago
Lead Electrical Engineer, Mission Critical
$138K - $184K *
Lead the design and execution of electrical systems for mission critical facilities, collaborating with teams to ensure high availability and efficiency. Oversee projects from concept to construction...
Yesterday
$130K - $160K *
Elevate cloud security and reliability by leading DevOps practices across teams. You'll optimize AWS and GCP environments, enhance CI/CD pipelines, and ensure cost-effective engineering tools, driving...
1 week ago
Vice President Contracts, Engineered Systems
$200K - $383K *
Join us to lead the contracts function in a dynamic Federal contracting environment. Oversee a team of 20+ professionals, develop strategies, and negotiate complex contracts while fostering strong rel...
2 weeks ago
$104K - $156K *
Join us to architect innovative financial systems, leading greenfield projects that enhance data management and analytics. Collaborate across teams to implement your vision and drive impactful solutio...
5 days ago
Senior Project Manager, Data Centers Project & Development Services
$148K - $175K *
Join a dynamic team as a Senior Project Manager, overseeing complex data center projects. Drive client engagement, ensure seamless collaboration, and deliver exceptional results while upholding high s...
2 weeks ago
Lead Engineer - Mechanical Design Build
$100K - $120K *
Transform the future of engineering by leading innovative mechanical designs for mission-critical facilities. Drive projects from concept to completion, ensuring reliability and efficiency in HVAC and...
Reposted 3 days ago
$80K - $95K *
Join a team that's dedicated to designing impactful airport engineering projects. Collaborate on construction plans and technical specifications while enhancing your skills in a fast-paced environment...
2 weeks ago
Isovalent (Cloud Native Security) Account Executive - Central
$261K - $356K *
Join a team that's driving enterprise growth by modernizing networking and security for cloud-native environments. Build executive relationships and engage technical stakeholders to exceed sales targe...
Reposted 1 week ago
CGI OpenGrid Implementation Consultant, Manager
$99K - $232K *
Shape the future of client operations by leading CGI OpenGrid implementations, guiding teams, and enhancing business application effectiveness through strategic consulting and training...
3 days ago
CGI OpenGrid Implementation Consultant, Manager
$99K - $232K *
Lead the charge in implementing CGI OpenGrid solutions, guiding teams and managing projects to enhance client operations. Utilize your expertise to deliver effective training and support, ensuring ali...
3 days ago
IT Administrator, Business Applications
$115K - $151K *
Administer and enhance collaboration platforms, ensuring seamless integration and automation across teams. Collaborate with cross-functional departments to optimize workflows and improve operational e...
1 week ago
Corporate Account Executive - SMB - West
$170K - $220K *
Accelerate your career by driving sales growth through strategic partnerships and innovative solutions in the cloud computing space. Collaborate with teams to achieve targets and enhance customer sati...
5 days ago
Senior Security Operations Engineer
$133K - $209K *
Join a dynamic IT team as you safeguard cloud infrastructure, enhance security measures, and lead incident response efforts. Your expertise will drive continuous improvement and ensure robust protecti...
3 weeks ago
Business Analyst, Service Logistics
$95K - $115K *
Drive logistics optimization and cost reduction initiatives across global service operations, enhancing efficiency and performance in transportation and network design while collaborating with cross-f...
Yesterday
Sr. Engineer, AI Cyber Security
$140K - $187K *
Innovate the future of AI security by designing and implementing robust defenses against adversarial threats, ensuring the integrity of AI systems while fostering innovation and collaboration across c...
3 weeks ago
$80K - $95K *
Drive impactful communications strategies that enhance brand messaging and support business goals. Collaborate with experts to create compelling content across various channels while managing complex...
2 weeks ago
Associate Director, Industry Technology Strategist - Enterprise
$201K - $239K *
Lead the charge in driving high-value sales pursuits, orchestrating teams and resources to shape winning strategies. Influence market offerings and account growth while championing excellence in clien...
2 weeks ago
DIRECTOR OF SECURITY ENGINEERING
$180K - $200K *
Reimagine security engineering leadership by guiding strategic initiatives across cloud and infrastructure security, enhancing detection engineering, and fostering collaboration to protect a multi-clo...
Reposted 1 week ago
Sr. Information Security Engineer
$120K - $145K *
Help us secure our cloud-based healthcare platforms by designing and implementing robust security solutions. This role demands expertise in cloud security, AI/ML protection, and compliance with indust...
4 weeks ago
Forward Deployed Engineer (New York)
$120K - $145K *
Build innovative AI solutions by collaborating with clients to tackle complex challenges. Design and deploy production-quality software while ensuring reliability and usability in real-world environme...
Reposted 4 days ago
$85K - $95K *
Collaborate with a dynamic team as a Structural BIM Technician to create detailed models, streamline design processes, and enhance interoperability in building projects, while upholding high-quality s...
Reposted 2 weeks ago
Global Resolution Engineer (Remote US)
$150K - $180K *
Innovate solutions as a Global Resolution Engineer, tackling complex escalations across diverse customer environments. Collaborate with teams to enhance product reliability and drive proactive improve...
2 weeks ago
Software Engineer II, Engineering
$125K - $145K *
Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...
Reposted 2 weeks ago
Principal Network Installation Technician (NIT 4)
$110K - $130K *
Champion complex network installation projects by leading teams, mentoring technicians, and ensuring high-quality service delivery. Collaborate with project managers and customers to meet objectives w...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.