Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$150K - $180K *

Champion the evolution of our billing systems by leading a dynamic engineering team. Drive strategy, ensure accuracy, and collaborate across departments to enhance customer trust as we scale our usage...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$89K - $105K *

Lead the charge in enhancing customer trust through security assurance and AI governance. This role focuses on maintaining accurate security documentation and optimizing AI agents to support governanc...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$114K - $145K *

Unlock your potential as a Data Engineer, transforming raw data into impactful systems. Collaborate with stakeholders, optimize data architecture, and drive efficiency through automation while managin...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$157K - $183K *

Unlock innovative Finance and Accounting outsourcing solutions by leading design and development efforts. Collaborate with cross-functional teams to optimize service delivery and drive strategic clien...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Join a team that's driving enterprise AI adoption by building a qualified pipeline through strategic outbound prospecting. Collaborate with Account Executives to engage key stakeholders and facilitate...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$129K - $210K *

Empower organizations by designing scalable data management solutions, collaborating with customers and partners to drive adoption and success. Act as a key technical advisor, bridging teams to ensure...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$98K - $163K *

Shape the future of enterprise software by building secure, scalable applications. Collaborate with cross-functional teams to integrate AI capabilities and deliver innovative solutions that meet busin...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$104K - $140K *

Help us drive innovation as a Principal Electrical Engineer, specializing in power systems. You will lead design teams, engage with customers, and develop cutting-edge power electronics to meet requir...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$175K - $225K *

Join a team that's dedicated to optimizing DevOps processes and infrastructure. Lead engineers in driving automation, scalability, and security while collaborating with cross-functional teams to enhan...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Join a team that's dedicated to safeguarding sensitive health information while enhancing security across cloud and application environments. As a Senior Security Engineer, you'll design and implement...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$124K - $198K *

Transform your career by owning and accelerating Unstructured data protection sales. Leverage your technical expertise to drive growth, engage stakeholders, and win competitive deals in a dynamic, quo...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $140K *

Join a team that's driving growth in unstructured data protection. Leverage your technical expertise to engage with clients, lead discovery, and close deals while collaborating with sales and engineer...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$103K - $181K *

Engage with us to design and automate public cloud environments, leveraging AI workflows. Collaborate in a fast-paced setting to enhance cloud operations and contribute to best practices while providi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$135K - $160K *

Lead the charge in architecting a cutting-edge Commercial Lines insurance platform, focusing on microservices and event-driven architecture. Collaborate with cross-functional teams to define and deliv...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$99K - $139K *

Join a dynamic team to develop and maintain innovative web applications, enhancing user experience and security. Collaborate with stakeholders to gather requirements, create documentation, and ensure...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Lead the SAP Analytics strategy and implementation, driving innovation in analytics solutions. Collaborate with stakeholders to deliver insights and manage teams, ensuring successful deployment of SAP...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$87K - $110K *

Empower customers through a shared portfolio approach, delivering seamless support and proactive engagement. Collaborate with teams to drive product adoption, ensure retention, and translate technical...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $251K *

Lead the charge in transforming customer experiences through innovative cloud security solutions, leveraging your expertise to craft tailored technical presentations and solutions that drive strategic...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Transform ideas into secure, scalable applications by collaborating with business users. Leverage modern AI tools and full-stack development skills to deliver innovative solutions in a fast-paced envi...

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $120K *

Drive product excellence by managing testing, documentation, and collaboration across teams. Engage with stakeholders to enhance solutions and ensure quality assurance for optimal deployment and suppo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$102K - $190K *

Lead and develop a high-performing team in firewall security engineering, ensuring consistent implementation of security controls while balancing operational demands and strategic initiatives for ente...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $190K *

Optimize cloud infrastructure and automate processes as a DevOps Engineer. Collaborate with cross-functional teams to enhance system reliability, scalability, and security while driving developer effi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$132K - $180K *

Drive impactful GTM systems strategy by optimizing processes and technology. Collaborate with cross-functional teams to enhance customer engineering workflows, ensuring alignment and continuous improv...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $146K *

Innovate strategic partnerships and drive revenue growth in NTN and IoT sectors. Cultivate relationships with global carriers, negotiate agreements, and identify new business opportunities to establis...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$95K - $115K *

Drive IT operations and support in a fast-growing environment, enhancing processes and automating workflows. Collaborate with cross-functional teams to scale IT infrastructure as the company expands f...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.