Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Principal Procore Administrator
$113K - $170K *
Join us as a Principal Procore Administrator to lead configuration, governance, and enhancement of Procore for enterprise facilities and construction operations, ensuring data integrity while collabor...
Reposted 2 weeks ago
Director, Technology Partner Architecture Solutions – Legal
$157K - $292K *
Elevate legal technology solutions by leading architecture design and integration with partners. Collaborate across teams to ensure scalable, secure offerings that meet customer needs while guiding a...
1 week ago
$101K - $157K *
Shape the future of BIM projects by leading a dynamic team, optimizing processes, and ensuring client satisfaction through effective management and strategic input across all phases of electrical cons...
3 weeks ago
Integrations Engineer, AI Services
$110K - $130K *
Unlock potential by designing and delivering scalable AI-powered integrations for nonprofits. Collaborate closely with clients to understand their needs, build solutions, and productize offerings that...
Yesterday
$110K - $130K *
Innovate by developing scalable applications and data pipelines, leveraging Python and cloud platforms. Collaborate with cross-functional teams to modernize enterprise systems and enhance backend serv...
3 weeks ago
$150K - $200K *
Join us to drive AI integration by transforming client workflows into live agents. You'll manage the entire process from scoping to deployment, collaborating with teams to deliver impactful solutions...
1 week ago
Solution Architect, Legal Billing
$130K - $145K *
Help us design and implement billing solutions for law firms, leveraging your accounting expertise and software skills to streamline time entry, invoicing, and collections processes on the Litify plat...
1 week ago
$110K - $130K *
Champion technical solution design and deployment readiness, translating customer needs into secure, scalable architectures. Collaborate with engineering and cybersecurity teams to ensure successful t...
1 week ago
$90K - $135K *
Engineer robust Kubernetes/OpenShift solutions, collaborating across teams to enhance container platform operations. Drive onboarding, maintain clusters, and optimize CI/CD pipelines for seamless appl...
2 weeks ago
$193K - $228K *
Lead the charge in transforming enterprise architecture by aligning technology with business goals, driving innovation, and managing technical debt to enhance application ecosystems and ensure scalabi...
Today
$95K - $115K *
Champion project delivery by overseeing HV cable testing projects across North America. Ensure alignment with client expectations while managing resources, schedules, and budgets for successful comple...
Reposted 1 week ago
Delivery Director-Telecommunications-ServiceNow TSOM, CSM, TI, FSM, OSS, BSS
$150K - $180K *
Lead the charge in driving operational excellence and portfolio growth, ensuring customer satisfaction and seamless delivery across innovative projects. Collaborate with sales and project teams to ele...
Reposted 2 weeks ago
$150K - $180K *
Drive the future of technical sales leadership by managing a team of Solutions Engineers, enhancing enterprise adoption of cutting-edge technologies, and ensuring technical wins through strategic part...
2 weeks ago
$114K - $145K *
Shape your career as a Data Engineer, transforming raw data into impactful systems. Collaborate with stakeholders, optimize data architecture, and drive efficiency through automation while managing co...
4 days ago
$100K - $110K *
Elevate your career by joining a dynamic Technical Operations team focused on cloud-native infrastructure and Kubernetes. Collaborate across teams to enhance platform reliability and drive operational...
Yesterday
$150K - $180K *
Lead the product vision and strategy for a cutting-edge cloud service, shaping capabilities and defining AI-driven insights while collaborating with engineering and operations teams to ensure market a...
6 days ago
$135K - $185K *
Transform enterprise architecture by defining our technology strategy, guiding scalable solutions, and leading modernization initiatives that align with business goals. Thrive in a role that fosters i...
Reposted 1 week ago
$120K - $145K *
Innovate and optimize CI/CD pipelines while integrating AI-driven automation to enhance developer enablement. Collaborate with agile teams to ensure secure, efficient software delivery and champion a...
Yesterday
Director of Security Operations and Engineering
$150K - $180K *
Empower security operations and engineering to enhance threat detection, incident response, and prevention. Collaborate with cross-functional teams to scale security measures as the organization grows...
3 weeks ago
Principal Architect, AI Enablement (Houston, TX Preferred OR United States - Remote)
$185K - $235K *
Transform engineering practices by leading AI Enablement initiatives, enhancing workflows, and driving adoption of AI standards across teams. Collaborate with stakeholders to measure progress and deli...
6 days ago
$92K - $110K *
Drive software quality and performance by leading testing strategies, facilitating design discussions, and ensuring system stability through hands-on coding and collaboration with cross-functional tea...
3 weeks ago
Manager, Endpoint Security Engineering
$102K - $190K *
Pioneer the future of endpoint security by leading a dynamic engineering team, ensuring operational excellence, and driving innovative capabilities to protect enterprise assets while aligning with bus...
1 week ago
Sr. Staff Cyber Defense Engineer
$181K - $301K *
Elevate our cyber defense capabilities by architecting advanced detection and response systems. Lead cross-functional initiatives, influence technical strategy, and enhance security measures to protec...
3 weeks ago
$95K - $115K *
Transform security protocols by designing, implementing, and managing comprehensive systems to safeguard data integrity, conduct risk assessments, and enhance incident response capabilities while ensu...
1 week ago
Microsoft Power Platform Tech Lead / Architect
$113K - $147K *
Pioneer innovative solutions as a Microsoft Power Platform Architect, leading enterprise-grade design and implementation. Collaborate with stakeholders to enhance efficiency, automate processes, and d...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.