Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$238K - $280K *

Lead the charge in developing autonomous attack workflows for external surfaces, leveraging your expertise to enhance reconnaissance capabilities and mentor engineers while driving strategic technical...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Partner with us to lead the deployment and integration of Palo Alto PA-450 firewalls within a Cisco SD-WAN environment, ensuring secure, efficient, and scalable multi-site rollouts while collaborating...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $185K *

Unlock potential by driving innovative infrastructure solutions for scalable deployments, collaborating with customers to refine requirements, and enhancing operational efficiency through automation a...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$141K - $278K *

Deliver innovative AI solutions by integrating Large Language Models into scalable applications. Collaborate with teams to align designs with technical strategy while ensuring security and performance...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$141K - $278K *

Empower us to design and implement innovative AI solutions that transform enterprise applications. Collaborate with a talented team to ensure robust and secure architectures, integrating advanced AI m...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$75K - $158K *

Champion operational excellence by managing the Avantra platform for SAP, ensuring secure, efficient monitoring and automation across diverse environments while collaborating with cross-functional tea...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $137K *

Lead the charge in cloud migration by managing infrastructure engineering tasks, executing migrations to Azure and AWS, and ensuring operational readiness for applications and services in a dynamic, r...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $155K *

Join a team that's dedicated to enhancing customer success by leading a high-performing group of CSMs. Drive measurable value across a diverse portfolio, ensuring operational excellence and fostering...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Empower your career by managing complex projects from inception to completion. You'll oversee proposals, budgets, and team coordination, ensuring adherence to safety and quality standards while delive...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$200K - $240K *

Join a dynamic team as you provide technical expertise, drive enterprise opportunities, and architect innovative solutions that meet client needs while showcasing the value of our cutting-edge product...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Join a team that's dedicated to optimizing data center operations and customer success. As a hands-on leader, you'll manage a skilled team, oversee implementations, and ensure operational excellence w...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by implementing and supporting AWS cloud solutions in a dynamic environment. Collaborate with experts to optimize performance and ensure secure, scalable infrastructure for federal...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$151K - $205K *

Discover innovative solutions as you design comprehensive technology architectures that align with client goals. Collaborate with teams to address needs, develop strategies, and ensure successful impl...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to transforming healthcare data solutions. As a Senior Data Engineer, you'll enhance complex systems, collaborate across departments, and drive analytics to optimize finan...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Champion project success by managing healthcare architecture initiatives from inception to completion. Lead diverse teams, engage clients, and ensure compliance with industry standards while deliverin...

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Solve security challenges by owning and enhancing our security program. Lead CorpSec, SecOps, and compliance efforts while building a robust security culture in a fast-paced, remote environment...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join our Cyber Security team to spearhead a robust application security program, collaborating with developers to secure software and mitigate vulnerabilities. Help innovate security tools while enhan...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Legal & Accounting

$207K - $310K *

Champion the Solutions Engineering team by driving technical sales strategies, managing performance, and fostering collaboration to meet organizational goals while ensuring customer success and team d...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$104K - $140K *

Take ownership of engineering projects, ensuring timely and budget-compliant delivery while leading cross-functional teams and liaising with various departments to meet customer specifications...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$88K - $105K *

Join a team that's dedicated to managing federal construction projects, ensuring quality and efficiency through estimating, scheduling, and collaboration with government representatives and design tea...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$87K - $293K *

Innovate with cutting-edge AI solutions, leading architecture for enterprise systems. Drive multi-agent designs and collaborate with clients to enhance business value while managing engineering teams...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$131K - $219K *

Join a team that's redefining cybersecurity in the energy sector. You'll lead complex projects, develop standards, and automate processes to enhance efficiency and security across global Grid Automati...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$130K - $155K *

Lead cross-functional engineering teams to enhance geospatial intelligence solutions, ensuring timely and accurate delivery through expert systems engineering, integration, and strategic planning acro...

5 days ago

  •   15+ years exp.  •   Business Services

$170K - $230K *

Join a team that's redefining SoC design by owning subsystem development, integrating third-party IP, and optimizing PPA for next-gen architectures. Contribute across all design stages and drive impac...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Join us to lead solution direction across multiple SAP engagements, ensuring customer value and platform adoption. Collaborate with teams to shape proposals, drive delivery, and influence product deve...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.