Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$80K - $95K *
Optimize our internal IT systems and security posture while managing user access, supporting AWS operations, and ensuring compliance. Collaborate with the COO to enhance efficiency and maintain a secu...
3 weeks ago
$145K - $157K *
Transform space operations by leveraging Kubernetes to deliver resilient solutions. Collaborate within an Agile framework to enhance software deployment, ensuring optimal performance and security for...
2 weeks ago
$140K - $165K *
Create innovative solutions as a Software Engineer, shaping a greenfield platform. Collaborate with teams to automate processes, build data infrastructure, and deliver impactful tools while enjoying a...
Yesterday
Advanced Cybersecurity Analytics Engineer III
$75K - $158K *
Innovate defensive cybersecurity strategies by analyzing data trends, developing countermeasures, and collaborating with teams to prevent compromises and enhance enterprise security. Drive proactive m...
2 weeks ago
$150K - $180K *
Elevate your career by engaging with clients to design and implement innovative technical solutions. Leverage your expertise in APIs and customer collaboration to drive impactful results in a fast-pac...
4 days ago
$136K - $160K *
Elevate operations through AI-driven automation to enhance incident management, streamline ticket resolution, and optimize service health with self-healing observability, all while collaborating acros...
Reposted 3 weeks ago
$95K - $115K *
Shape quality standards by leading design and construction oversight, ensuring compliance and continuous improvement across all project phases while mentoring teams and collaborating with stakeholders...
1 week ago
Senior Partner Solutions Architect, Strategic Partnerships
$115K - $194K *
Lead the technical strategy for strategic partnerships, transforming partner needs into integrations and influencing product design. Collaborate with R&D to evaluate AI models and enhance GitLab's off...
2 weeks ago
$175K - $195K *
Unlock innovative solutions as a Salesforce Solution Architect, leading design and implementation efforts to meet strategic business needs. Collaborate with stakeholders to deliver maximum value and d...
Today
$120K - $145K *
Shape the future of Salesforce solutions by designing and implementing innovative architectures that meet client needs. Collaborate with stakeholders to deliver high-value solutions in a dynamic, fast...
2 weeks ago
Open Talent Network: Staff DevOps and Systems Integration Engineer
$160K - $180K *
Transform the future of cloud infrastructure by leading DevOps initiatives, enhancing systems integration, and driving innovative solutions for federal clients. Collaborate with stakeholders to optimi...
Reposted 6 days ago
$110K - $130K *
Lead the charge in enhancing cloud security by conducting proactive reviews, managing complex incidents, and collaborating with cross-functional teams to improve detection and response mechanisms whil...
2 weeks ago
Principal AI Solutions Architect
$220K - $310K *
Empower businesses by architecting and deploying innovative AI solutions that leverage graph databases and LLMs. Collaborate with stakeholders to transform complex data challenges into impactful appli...
5 days ago
Senior Engineer, Data Engineering
$144K - $165K *
Unlock potential by owning data architecture and reliability across domains. Collaborate with an AI-first team to design robust data pipelines, enhance analytics, and drive impactful solutions in a dy...
6 days ago
$83K - $118K *
Unlock your potential by leading complex IT/SaaS projects, driving execution, and enhancing business processes. Collaborate with diverse teams to ensure project success while utilizing Agile methodolo...
4 weeks ago
$110K - $130K *
Lead innovative digital solutions by architecting and developing D365 and Power Platform applications. Collaborate with clients to enhance their systems while mentoring a team of developers to ensure...
6 days ago
$143K - $179K *
Analyze customer experiences to drive retention strategies and enhance satisfaction. Collaborate across teams to shape data-driven decisions, develop metrics, and prioritize analytics initiatives that...
Yesterday
Senior Infrastructure Engineer- Secure Developer Platforms (Azure/VDI)
$125K - $150K *
Lead the charge in building a secure, self-service developer sandbox on Azure, delivering non-persistent desktops and managing the entire stack from landing zone to golden image while ensuring complia...
1 week ago
Lead Solution Architect, Physical AI
$140K - $175K *
Transform the landscape of Physical AI by leading technical design and delivery of innovative systems that integrate computer vision, robotics, and digital twin technologies, ensuring seamless operati...
3 weeks ago
Solutions Engineer Technical Lead
$95K - $115K *
Lead client interactions and drive technology solutions by leveraging AI and best practices. Collaborate with teams to enhance efficiency, mentor developers, and ensure alignment with business goals w...
5 days ago
$135K - $160K *
Champion modernization initiatives by designing and overseeing transformation solutions, integrating cutting-edge GenAI technology, and ensuring alignment with business objectives to drive impactful m...
Reposted 3 weeks ago
$100K - $120K *
Lead the charge in enhancing security for a complex federal platform, safeguarding cloud infrastructure and sensitive data. Collaborate within an Agile team to design, implement, and automate robust s...
2 weeks ago
Lead Consultant - Network Security
$98K - $167K *
Innovate within our network security team by leading the engineering and automation of enterprise security platforms. Drive technical excellence and enhance infrastructure management through modern pr...
2 weeks ago
Oracle Fusion Financial Architect
$98K - $206K *
Bring your expertise to architect solutions in Oracle Fusion Financials, enhancing federal financial operations for military logistics. Lead design efforts to ensure compliance and data integrity acro...
Reposted 2 weeks ago
Mainframe Systems Programmer - Network
$65K - $126K *
Join a team that's dedicated to optimizing mainframe network systems. Leverage your expertise in planning, installing, and maintaining software while ensuring system performance and reliability. Colla...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.