Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$110K - $130K *

Unlock potential by joining a dynamic team of Solution Consultants, delivering expert guidance on Atlassian products to help clients maximize their investments and achieve strategic outcomes in the Pu...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$91K - $118K *

Accelerate your career by driving technical solutions and proposals for engineered equipment. Collaborate with sales and engineering teams to ensure customer satisfaction and secure new business oppor...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$82K - $172K *

Transform your career by leading the integration of Oracle EBS and Cloud EPM. Spearhead data flow management and architectural redesign while collaborating with technical teams to enhance financial sy...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Transform the Central Region's channel strategy by leading a high-performing team, driving revenue growth, and fostering strategic partnerships. Collaborate with executives to align goals and maximize...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $220K *

Transform the product marketing landscape by leading go-to-market strategies for cutting-edge AI and cloud solutions. Collaborate cross-functionally to craft compelling narratives that resonate with c...

United StatesRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Information Technology

$105K - $130K *

Lead the charge in executing automation projects across North America, focusing on facility layout and equipment installation while ensuring safety and operational excellence through collaboration and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$135K - $160K *

Empower our data platform by designing, building, and operating core capabilities. Collaborate with teams to enhance ingestion, storage, and API functionalities, ensuring scalability and resilience wh...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $145K *

Elevate public health data interoperability by designing and implementing secure, scalable data pipelines. Collaborate with cross-functional teams to modernize legacy systems and ensure compliance, dr...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$109K - $251K *

Lead the charge in delivering advanced technology solutions, ensuring customer satisfaction through effective consulting and relationship management. Shape technical strategies and contribute to busin...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$82K - $172K *

Join us to provide vital support as an Acquisition Specialist, overseeing multi-million dollar contracts in naval shipbuilding. Ensure compliance, manage contractor performance, and drive strategic al...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Join a team that's transforming supply chain operations through Oracle Fusion SCM. Lead the design and configuration of inventory solutions, ensuring real-time visibility and accountability for critic...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$153K - $166K *

Empower the future of education by developing scalable web applications and cloud services. Collaborate with cross-functional teams to enhance digital assessment experiences, ensuring reliability and...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Transform complex data systems by designing and implementing scalable solutions that enhance analytics and drive business intelligence in a collaborative, Agile environment focused on healthcare compl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $185K *

Unlock your potential by leading the design and implementation of innovative digital solutions for Veteran healthcare services. Collaborate with cross-functional teams to enhance enterprise applicatio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$155K - $226K *

Elevate Cisco's CX partner strategy by collaborating with leaders to enhance global growth through innovative observability solutions and technical guidance, ensuring successful partner implementation...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$170K - $185K *

Champion innovative software solutions by leading complex projects, mentoring engineers, and driving technical excellence across teams. Collaborate on strategic initiatives to enhance reliability and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $137K *

Lead the charge in transforming workflows with AI, driving adoption and measurable impact in legal, tax, and trade sectors. Collaborate with clients and teams to design, implement, and evaluate innova...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$120K - $130K *

Champion quality and commissioning excellence across diverse construction projects, ensuring compliance and safety while fostering collaboration among teams and stakeholders to drive impactful results...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$250K - $300K *

Lead the charge in driving enterprise sales by collaborating with Microsoft teams to identify and capitalize on AVD opportunities. Leverage your expertise in VDI and EUC technologies to foster relatio...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Strategize and lead global solution marketing initiatives to enhance customer engagement and drive growth in the data center and smart building sectors, collaborating closely with product management a...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Drive innovative electrical engineering solutions for complex industrial projects. Lead multidisciplinary teams from concept to construction, ensuring quality and client satisfaction while fostering b...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$88K - $105K *

Engage in comprehensive finance integration for acquired companies, ensuring accurate data mapping, system conversion, and post-close stabilization. Collaborate with cross-functional teams to streamli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $189K *

Lead, shape, and execute advanced penetration testing assessments, overseeing scoping, planning, and reporting. Collaborate with teams to enhance cybersecurity measures across various platforms, ensur...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $132K *

Help us drive growth as a strategic Channel Account Manager, collaborating with partners to create scalable sales strategies, enhance engagement, and achieve measurable outcomes in the enterprise tech...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in advancing AI applications in healthcare by developing intelligent agents that uncover financial opportunities within complex datasets, transforming manual analyses into scalable wor...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.