Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$106K - $150K *

Unlock potential by providing expert operational support for Windows environments. Manage complex incidents, ensure service availability, and collaborate across teams to enhance customer experiences i...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $135K *

Elevate your career by designing and implementing cloud infrastructure solutions in Azure. Collaborate with teams to automate deployments, optimize CI/CD pipelines, and leverage AI tools for enhanced...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$117K - $170K *

Lead the charge in developing innovative Digital Experience solutions, collaborating with customers and internal teams to drive growth. Provide expert guidance in unified communications and build stra...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Transform AI infrastructure by designing and maintaining production-grade systems across multiple cloud providers. Engage in hands-on architecture decisions, ensuring reliability, security, and automa...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$133K - $200K *

Champion the delivery of advanced manufacturing capabilities by leading cross-functional teams, managing project lifecycles, and ensuring alignment with customer and stakeholder expectations for succe...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$206K - $242K *

Transform external attack capabilities by developing scalable workflows and automating reconnaissance processes. Drive innovation in offensive security, mentor teammates, and contribute to a high-impa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$122K - $180K *

Accelerate product development by defining, designing, and prototyping features for partner integrations, leveraging AI tools and user feedback to enhance payment processing solutions and maintain com...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $110K *

Shape the future of electrical power systems by designing innovative substation layouts and construction packages. Collaborate with multidisciplinary teams to ensure compliance with industry standards...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$260K *

Join a team that's driving digital transformation by managing client accounts, developing strategies, and delivering innovative technology solutions. Build long-term relationships while collaborating...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $120K *

Join a dynamic team to lead and enhance information security programs, ensuring compliance and risk management across diverse industries. Collaborate with executives to develop strategies that protect...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$123K - $166K *

Join a team that's dedicated to enhancing cloud platform reliability and security. As a Platform Engineer, you'll leverage your expertise in Kubernetes and CI/CD to build and maintain robust infrastru...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$98K - $164K *

Explore innovative technical architectures and solutions in energy management. Collaborate with teams to deliver digital substations and automation systems while engaging with customers from design to...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Shape the future of product design by transforming concepts into high-fidelity experiences. Collaborate with cross-functional teams to enhance user interactions through innovative prototyping and AI-a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $133K *

Lead the charge in delivering innovative full-stack solutions, collaborating with diverse teams to modernize applications on AWS using cutting-edge technologies, ensuring operational resilience and me...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $133K *

Champion innovative solutions by collaborating with cross-functional teams to develop scalable, cloud-native applications. Leverage your full-stack expertise to modernize systems and deliver high-valu...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$170K - $200K *

Advance backend solutions and frontend features, collaborating across teams to build scalable systems and AI integrations, driving product growth from conception to execution...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$98K - $206K *

Join a dynamic team as a Senior CSfC Systems Engineer, deploying cutting-edge networking solutions across the U.S. and globally. Leverage your expertise in virtualization and data center architecture...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$240K *

Lead enterprise cybersecurity and infrastructure initiatives, advising executive leadership on risk management and technology investments. Shape policies and governance to ensure a secure, resilient t...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$170K - $325K *

Elevate your career by securing and managing the transition to a hybrid-cloud infrastructure. Own identity management, cloud security, and developer tooling while leading incident response and threat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$187K - $220K *

Unlock potential by designing and building AI-powered solutions to enhance enterprise IT operations, collaborating directly with customers and driving impactful product features across backend and aut...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$122K - $183K *

Elevate user growth and monetization through thoughtful design and experimentation, collaborating closely with cross-functional teams to enhance onboarding and product engagement while maintaining hig...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $158K *

Shape the future of federal data integration by leveraging Oracle EBS expertise to create actionable insights and advanced dashboards. Collaborate with cross-functional teams and enhance government da...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$204K - $216K *

Unlock potential by designing robust data models that empower AI systems. You will ensure data coherence and quality, bridging knowledge representation and machine learning across diverse communities...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's shaping the future of interconnect technology by designing innovative connector solutions. Leverage your engineering expertise to collaborate globally and meet the demands of leadin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K *

Drive enterprise-level implementations of phishing-resistant authentication solutions, leading technical deployments and integrations across various identity platforms while ensuring customer success...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.