Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$120K - $185K *

Transform the future of engineering design by leading diverse teams to deliver high-quality electrical engineering solutions. Drive project success through strategic oversight, mentoring, and adherenc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$165K - $248K *

Lead enterprise-scale operations for cloud services, ensuring performance and customer satisfaction. Drive a multidisciplinary team, manage service transitions, and leverage data-driven metrics to enh...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$63K - $111K *

Lead the procurement process as a Senior Subcontract Administrator, managing subcontractor relationships, negotiating agreements, and ensuring compliance with industry standards. Drive efficiency in t...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $160K *

Join a team that's transforming healthcare with AI solutions. As an AI Solutions Engineer, you'll develop integrations and tools that enhance customer workflows, bridging the gap between clients and o...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in designing and evolving scalable cloud infrastructure, driving architectural strategy, and enhancing operational culture while collaborating with cross-functional teams to meet ambit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$179K - $232K *

Empower the future of passenger travel by leading architectural innovation. Collaborate across teams to define strategic technology roadmaps, ensuring alignment with business goals while driving effic...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Transportation

$110K - $130K *

Join a team that's shaping the future of large-scale data center design. Leverage your civil BIM expertise to develop and coordinate complex models, ensuring seamless integration of infrastructure and...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$200K - $300K *

Pioneer partner success by leading technical enablement for contact center solutions. Drive onboarding, co-selling support, and strategic architecture using Zendesk and AWS technologies to empower par...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$154K - $221K *

Lead the charge in shaping the sales engineering team for core solutions, driving revenue growth through strategic partnerships and innovative problem-solving in a dynamic environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$163K - $204K *

Partner with us to architect and enhance our next-gen web console, driving frontend infrastructure and user experience across multiple products while ensuring robust security and seamless integration...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$82K - $172K *

Accelerate progress at the intersection of security and cloud infrastructure, leading a team to optimize AWS environments, implement DevSecOps practices, and enhance automation for secure software del...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$122K - $160K *

Transform the future of endpoint management by developing innovative solutions that enhance security and performance across diverse platforms, collaborating with a dynamic team to deliver impactful so...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Join a team that's advancing national security by securing our infrastructure. Work collaboratively in a dynamic environment to enhance IT engineering efforts, ensuring compliance and safeguarding cru...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$130K - $150K *

Lead strategic sales initiatives within the public sector, driving new business and expanding existing accounts. Manage complex SaaS deals, build strong relationships, and deliver tailored solutions t...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $220K *

Champion the development of an integrated energy strategy platform, overseeing program management and collaboration with sister companies to enhance utility power procurement and behind-the-meter gene...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $165K *

Optimize commissioning processes by collaborating with teams to ensure quality and adherence to standards. Drive issue resolution and continuous improvement in mission-critical environments, enhancing...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $165K *

Elevate your career by leading commissioning efforts in mission-critical environments. Collaborate with diverse teams to ensure quality assurance, risk mitigation, and successful project delivery whil...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $165K *

Join us to drive excellence in commissioning processes, ensuring quality and reliability in mission-critical facilities. Collaborate with diverse teams to enhance operational readiness and implement b...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by leading the design of innovative applications that empower network teams. Collaborate with cross-functional teams to create user-centric solutions, transforming complex data into i...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$89K - $125K *

Partner with us to integrate new firms into our IT environment, managing Microsoft 365 migrations and Active Directory consolidations while collaborating with cross-functional teams to ensure seamless...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in database operations, ensuring optimal performance and security for mission-critical systems. Oversee a technical team while aligning with federal standards and integrating with deve...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$75K - $103K *

Unlock potential by leading strategic partnerships and driving revenue growth through effective management of Fortinet business development resources and collaboration with sales teams...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Join a team that's redefining enterprise data management by leading the design and delivery of Informatica MDM solutions. Leverage your expertise to create scalable data models and governance processe...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Champion growth in smart manufacturing by managing key accounts, driving sales, and fostering relationships within the Industry 4.0 ecosystem. Leverage technical expertise to support IIoT adoption and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $90K *

Unlock potential by exploring various technology disciplines at the Designer I level. Collaborate with mentors, gain hands-on experience, and apply fundamental skills across ICT, Security, AV, and mor...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.