Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Principal Technical Program Manager, Engineering
$180K - $240K *
Drive cross-domain visibility and coordination in a dynamic engineering environment. As the sole TPM, you'll ensure programs are on track, dependencies are mapped, and automation enhances efficiency a...
1 week ago
Senior/Staff Software Engineer (Platform and Execution Model)
$180K - $240K *
Transform the future of distributed systems by designing and building robust platform components. Collaborate with teams to ensure reliability and scalability in mission-critical environments, driving...
4 weeks ago
$120K - $170K *
Transform enterprise software systems by leading design and development efforts, ensuring scalable, secure applications that meet federal mission needs while mentoring engineers and driving best pract...
2 weeks ago
Operational Technology (OT) Engineer
$76K - $118K *
Explore a pivotal role in enhancing operational technology solutions for Army facilities. Collaborate with diverse teams to ensure system security, reliability, and compliance while supporting moderni...
2 weeks ago
$100K - $120K *
Drive the development and integration of advanced nuclear energy systems by applying systems engineering methods to translate objectives into clear, verifiable requirements and solutions, while collab...
2 weeks ago
Salesforce Architect | Public Health | Public Sector
$145K - $150K *
Grow your career with a collaborative team focused on public health solutions. As a Senior Salesforce Developer, you'll leverage your expertise to enhance health department systems nationwide within a...
2 weeks ago
$120K - $140K *
Drive the development and optimization of GTM strategies, leveraging automation and campaign execution across multiple platforms to enhance pipeline generation and account prioritization in a dynamic...
Reposted 1 week ago
$120K - $145K *
Join a team that's driving financial excellence in manufacturing operations. As a strategic partner, you'll enhance profitability through insightful analysis, budgeting, and capital management while f...
2 weeks ago
Senior Manager, Software Development
$145K - $225K *
Lead the charge in software development, driving innovation and collaboration across teams. Oversee strategic planning and team development to enhance product quality and efficiency, while fostering a...
2 weeks ago
$168K - $210K *
Lead the transformation of our build and deploy systems while enhancing developer efficiency, safety, and software delivery reliability. Collaborate across teams to drive technical innovation and opti...
Reposted 5 days ago
$135K - $160K *
Lead the development and operation of a cutting-edge Security Observability & Data Platform, enhancing endpoint security, threat detection, and incident response while driving innovation in security s...
Reposted yesterday
Forward Deployed Consultant, Manufacturing
$125K - $150K *
Drive AI transformations in manufacturing by collaborating with C-level executives to identify high-impact opportunities, build tailored solutions, and achieve measurable results in core operating pro...
Reposted today
Account Executive - East Coast
$100K - $120K *
Elevate traffic management solutions by driving revenue through strategic partnerships with government agencies. Cultivate relationships, identify opportunities, and execute sales strategies to achiev...
1 week ago
$120K - $185K *
Transform the future of engineering design by leading diverse teams to deliver high-quality electrical engineering solutions. Drive project success through strategic oversight, mentoring, and adherenc...
1 week ago
Principal Cloud Operations Manager
$165K - $248K *
Lead enterprise-scale operations for cloud services, ensuring performance and customer satisfaction. Drive a multidisciplinary team, manage service transitions, and leverage data-driven metrics to enh...
Reposted 3 weeks ago
Subcontract Administrator (Remote)
$63K - $111K *
Lead the procurement process as a Senior Subcontract Administrator, managing subcontractor relationships, negotiating agreements, and ensuring compliance with industry standards. Drive efficiency in t...
3 weeks ago
$100K - $160K *
Join a team that's transforming healthcare with AI solutions. As an AI Solutions Engineer, you'll develop integrations and tools that enhance customer workflows, bridging the gap between clients and o...
4 weeks ago
Senior Infrastructure Engineer
$120K - $145K *
Lead the charge in designing and evolving scalable cloud infrastructure, driving architectural strategy, and enhancing operational culture while collaborating with cross-functional teams to meet ambit...
1 week ago
Distinguished Architect - Passenger Travel Experience - Remote
$179K - $232K *
Empower the future of passenger travel by leading architectural innovation. Collaborate across teams to define strategic technology roadmaps, ensuring alignment with business goals while driving effic...
4 days ago
Senior Partner Platform Architect
$200K - $300K *
Pioneer partner success by leading technical enablement for contact center solutions. Drive onboarding, co-selling support, and strategic architecture using Zendesk and AWS technologies to empower par...
2 weeks ago
Manager, Sales Engineering - SMB
$154K - $221K *
Lead the charge in shaping the sales engineering team for core solutions, driving revenue growth through strategic partnerships and innovative problem-solving in a dynamic environment...
1 week ago
$163K - $204K *
Partner with us to architect and enhance our next-gen web console, driving frontend infrastructure and user experience across multiple products while ensuring robust security and seamless integration...
2 days ago
$82K - $172K *
Accelerate progress at the intersection of security and cloud infrastructure, leading a team to optimize AWS environments, implement DevSecOps practices, and enhance automation for secure software del...
Reposted 2 weeks ago
Software Engineer - Agent Team
$122K - $160K *
Transform the future of endpoint management by developing innovative solutions that enhance security and performance across diverse platforms, collaborating with a dynamic team to deliver impactful so...
Reposted 1 week ago
$100K - $120K *
Join a team that's advancing national security by securing our infrastructure. Work collaboratively in a dynamic environment to enhance IT engineering efforts, ensuring compliance and safeguarding cru...
Reposted 2 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.