Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
$139K - $235K *
Lead the development of innovative CX solutions using AI tools, enhancing workflows and integrations across platforms. Collaborate with cross-functional teams to deliver production-quality software an...
Yesterday
$120K - $145K *
Lead the charge in developing innovative AI software solutions, enhancing system performance, and collaborating with teams to align with IT roadmaps. Drive improvements through analysis and ensure sea...
2 days ago
Builder Developer II/III/IV (Senior Agentic Software Engineer)
$120K - $145K *
Transform enterprise software development by leveraging AI to create autonomous agents and workflows. Drive modernization of legacy systems with innovative solutions, focusing on automation and archit...
1 week ago
$150K - $170K *
Join a team that's dedicated to overseeing construction projects, ensuring compliance with safety regulations, and driving operational excellence. Lead on-site teams, manage budgets, and collaborate w...
5 days ago
Experienced Info Security Engineer (Product Owner Role)
$104K - $191K *
Accelerate progress at the forefront of cybersecurity by driving AI and automation initiatives. Collaborate with security teams to identify opportunities, coach on new tools, and enhance organizationa...
6 days ago
$129K - $210K *
Transform issue management by leading a team to develop AI-assisted solutions, ensuring quality and accountability in remediation processes across GRC. Drive engineering excellence while fostering ind...
5 days ago
Senior Director, Site Reliability Engineering
$175K - $250K *
Lead the charge in enhancing the reliability and scalability of a global multi-tenant platform. Drive SRE strategy, foster collaboration across teams, and ensure operational excellence while developin...
1 week ago
Director, Mainframe Systems Programming
$135K - $205K *
Lead the charge in delivering client-focused mainframe solutions. Oversee diverse projects, manage teams, and leverage strategic insights to enhance hardware and software lifecycle management while fo...
4 weeks ago
Manager, Customer Success - Americas
$110K - $130K *
Elevate customer success in the Americas by leading a growing team of CSMs. Drive adoption, value realization, and customer health while shaping playbooks and strategies for scalable growth. Collabora...
1 month ago
Ecosystem Operations Specialist
$86K - $146K *
Join us to execute and enhance partner operations, ensuring seamless workflows and data integrity. Collaborate with cross-functional teams to support sales and partners, driving efficiency and operati...
1 week ago
Associate Engineer - Infrastructure & Integrations Support
$73K - $91K *
Engage in operational support for enterprise infrastructure and integration applications. Utilize your expertise in Linux and Windows environments, scripting, and automation to enhance reliability and...
Yesterday
Member of Engineering, Backend - AI
$250K - $250K+*
Pioneer the future of developer AI by architecting scalable backend systems that enhance real-world product experiences through developer-centric cloud infrastructure...
Reposted 4 days ago
IT Systems Engineer Lead - Security
$125K - $135K *
Redefine security monitoring and vulnerability management by leading an Agile team to enhance IT infrastructure security. Collaborate on software design and implementation while ensuring robust remedi...
2 days ago
Strategic Accounts Manager, Data Centers - US Robotics West
$110K - $130K *
Join a pioneering team driving sales growth in the data center segment. You'll develop strategies, manage key accounts, and lead a virtual team to enhance customer satisfaction and deliver value in a...
1 week ago
REMOTE - Principal Platform Software Engineer- Oracle Health
$105K - $234K *
Lead the design and delivery of complex platform capabilities, enhancing reliability and security while mentoring engineers. Collaborate across teams to drive technical excellence and implement AI-ass...
1 week ago
Software Engineer - Data Platform (R37)
$105K - $202K *
Engineer robust data platforms by designing scalable pipelines and APIs that support AI-driven healthcare applications, ensuring high performance, security, and operational excellence in a collaborati...
Reposted 2 days ago
$90K - $189K *
Optimize SAP environments by administering S/4HANA systems, ensuring stability and performance. Collaborate across teams to lead upgrades and cloud transitions, enhancing enterprise resilience and sup...
1 week ago
$150K - $180K *
Elevate data privacy standards by leading a comprehensive privacy program. Collaborate across teams to integrate privacy-by-design principles, enhance data governance, and ensure compliance while enab...
3 weeks ago
Service Delivery Manager - Security & Governance
$150K - $164K *
Lead our cybersecurity and governance initiatives, enhancing security operations and risk management while driving compliance with CMMC 2.0 and ISO/IEC 27001 standards. Collaborate across teams to imp...
2 weeks ago
Staff Software Engineer, Data Systems (Python)
$190K - $220K *
Champion robust data integration while collaborating with cross-functional teams to design and optimize data pipelines, directly influencing our rapidly scaling marketing intelligence platform's succe...
Reposted today
Director, Energy Strategy & Development, New Markets
$195K - $250K *
Lead the charge in defining and executing energy strategies for new markets, ensuring sustainable power infrastructure aligns with growth objectives. Collaborate with stakeholders to unlock capacity a...
3 weeks ago
Senior Infrastructure & Platform Engineer
$130K - $175K *
Engineer and optimize enterprise platforms for diverse environments, ensuring seamless deployment and support. Collaborate with clients to enhance cybersecurity, compliance, and observability solution...
Reposted 4 days ago
$105K - $163K *
Transform database environments by leading architecture and administration efforts across multiple platforms, ensuring compliance and performance for mission-critical applications in a dynamic, remote...
3 weeks ago
$100K - $120K *
Transform payment strategies by analyzing interchange and routing data to optimize costs and enhance performance. Leverage advanced analytics and automation to deliver actionable insights for stakehol...
6 days ago
$75K - $110K *
Shape the financial landscape by driving month-end close processes, ensuring general ledger accuracy, and enhancing accounting practices in a dynamic, multi-revenue stream environment. Collaborate to...
4 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.