Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$184K - $230K *

Shape the future of product security by leading architecture reviews and risk mitigation strategies. Collaborate with engineering and compliance teams to embed security throughout the development life...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Partner with us to drive innovative solutions as a Principal Architect, engaging in multi-faceted pre-sales and delivery efforts. Collaborate with teams and clients to enhance customer experiences and...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K - $130K *

Drive the design and enhancement of corporate security infrastructure, improving automation and maintaining strong security posture in a cloud environment. Collaborate with teams to implement controls...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K *

Drive AI innovation by designing and scaling enterprise solutions that enhance business outcomes. Collaborate with cross-functional teams to ensure secure, compliant, and effective AI implementations...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$124K - $138K *

Transform mission-critical outcomes as a Senior Systems Engineer with expertise in MBSE and digital engineering. Drive program milestones, mentor junior engineers, and lead complex systems engineering...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$82K - $123K *

Champion AI innovation by driving tool adoption, engineering practices, and workforce enablement across the enterprise. Collaborate with cross-functional teams, influencing leaders and building future...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$98K - $206K *

Join a team that architects Oracle Fusion PPM solutions to enable precise project management and financial accountability for Marine Corps initiatives. Leverage your expertise to lead configurations a...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$175K *

Shape the future of global telecommunications by leading strategy, architecture, and operations for voice and video infrastructure, ensuring reliable and cost-effective communication services aligned...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Shape the future of online payments by driving revenue growth and optimizing checkout experiences. Collaborate with sales and engineering teams to influence product strategy and enhance customer relat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $250K *

Unlock innovative infrastructure solutions by collaborating with cross-functional teams to design scalable architectures that meet client needs and enhance operational efficiency across data centers...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$103K - $138K *

Unlock potential by designing and automating secure, scalable AWS cloud platforms. Collaborate with cross-functional teams to enhance infrastructure reliability and streamline software delivery throug...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$152K - $190K *

Unlock potential by delivering tailored data governance strategies and architectural designs for federal agencies, ensuring compliance and driving measurable outcomes while collaborating cross-functio...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive your career with a pivotal role in systems engineering, bridging design and compliance teams to select cutting-edge technologies for military-grade products, ensuring high performance and reliab...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the selection of advanced electronics technologies, bridging design and compliance engineering to ensure high-performance product development for military applications...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $140K *

Transform your career by leading complex design change projects from inception to execution. Collaborate with cross-functional teams, manage substantial budgets, and drive innovation in a fast-paced e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$183K - $306K *

Drive the architectural vision for a cutting-edge platform, ensuring scalability, security, and efficiency. Collaborate across teams to modernize systems while maintaining client trust and operational...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$63K - $111K *

Transform your career by joining a dynamic team as a Security Technician, where you'll travel to install, troubleshoot, and maintain advanced electronic systems, ensuring operational excellence across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $170K *

Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$157K - $283K *

Transform transit operations by leading complex Automatic Train Supervision initiatives. Drive collaboration across technical and operational teams, ensuring system performance and reliability for maj...

United StatesRemote

2 weeks ago

  •   15+ years exp.  •   Real Estate & Construction

$80K - $95K *

Optimize our internal IT systems and security posture while managing user access, supporting AWS operations, and ensuring compliance. Collaborate with the COO to enhance efficiency and maintain a secu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$145K - $157K *

Transform space operations by leveraging Kubernetes to deliver resilient solutions. Collaborate within an Agile framework to enhance software deployment, ensuring optimal performance and security for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $180K *

Elevate your career by engaging with clients to design and implement innovative technical solutions. Leverage your expertise in APIs and customer collaboration to drive impactful results in a fast-pac...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$136K - $160K *

Elevate operations through AI-driven automation to enhance incident management, streamline ticket resolution, and optimize service health with self-healing observability, all while collaborating acros...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$115K - $194K *

Lead the technical strategy for strategic partnerships, transforming partner needs into integrations and influencing product design. Collaborate with R&D to evaluate AI models and enhance GitLab's off...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $195K *

Unlock innovative solutions as a Salesforce Solution Architect, leading design and implementation efforts to meet strategic business needs. Collaborate with stakeholders to deliver maximum value and d...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.