Mission Systems Engineer Jobs

At Ladders, we connect you with the best available Mission Systems Engineering jobs that pay over $100,000 a year. Mission Systems Engineers play an essential role in the development, operation, and application of both hardware and software systems in aerospace and defense sectors.

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With listings from a wide variety of industries, you can find a position that fits your unique skill set. Quality assured with vetted opportunities from leading companies.

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Aim for the stars with high salaried jobs in Mission Systems Engineering. Leverage your expertise to land a six-figure job that matches your career goals.

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$182K - $228K *

Champion engineering excellence by leading teams that drive secure, scalable software solutions for our digital pharmacy platforms, ensuring operational efficiency while enhancing patient access and a...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$157K - $298K *

Lead cybersecurity compliance efforts by aligning security practices with business objectives. Collaborate with leaders to identify risks, drive governance, and support regulatory readiness, ensuring...

US-AnywhereRemote

2 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $110K *

Join a team that designs, develops, and implements testing methods to ensure product performance. Oversee all test activities, manage a testing team, and drive continuous improvement through detailed...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$76K - $95K *

Drive data stewardship and service lifecycle management to enhance operational efficiency and support informed decision-making across global service teams. Collaborate with cross-functional partners t...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$155K - $180K *

Empower your career by leading SCADA systems integration for energy projects. Oversee technical architecture, coordinate cross-functional teams, and ensure robust data connectivity across diverse rene...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$99K - $120K *

Transform project execution through effective coordination in building automation systems, ensuring compliance and managing communication between stakeholders. Work independently to oversee routines a...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $130K *

Drive successful MES project delivery through strategic management of scope, budget, and quality. Collaborate across departments to ensure system integrity and compliance with regulatory standards, op...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$134K - $223K *

Transform the HR landscape by developing AI-driven automations and data infrastructures that enhance operational efficiency and employee experience, while ensuring compliance and governance of sensiti...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$195K - $290K *

Drive the design and deployment of cutting-edge data platforms for AI-driven security solutions. Lead a team in optimizing large-scale systems, focusing on LLM integration and agile delivery while ens...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $175K *

Drive human factors engineering strategies to enhance safety at a pioneering nuclear recycling facility, ensuring effective personnel operations and reducing human error through interdisciplinary coll...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$131K - $135K *

Bring your expertise to our Autonomous Controls Team, developing robust simulation models for haulage vehicles. Collaborate on advanced control algorithms to enhance vehicle motion control and optimiz...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Transportation

$90K - $120K *

Engage in large-scale healthcare claims projects, balancing Agile delivery with strategic project management to enhance platform modernization and drive transformation initiatives across teams...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$118K - $196K *

Drive impactful foreign assistance programs to enhance global tech security. Oversee strategic planning, technical assistance, and stakeholder engagement for international projects, ensuring effective...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$90K - $120K *

Join a collaborative team focused on software development and geospatial data analysis. Utilize Python, GIS tools, and version control to drive innovative solutions and streamline processes in a dynam...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Transform security solutions by owning the VMS product, driving AI-native strategies, and shaping product discovery practices. Collaborate across teams to deliver impactful outcomes in a fast-paced, i...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $300K *

Lead the charge in building innovative SAP solutions that enhance core operations. Oversee engineering teams, drive architectural decisions, and collaborate cross-functionally to align technology with...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$103K - $125K *

Strategize global supply for GPU/CPU compute infrastructure, managing OEM/ODM relationships, overseeing accelerator allocations, and ensuring seamless continuity across data centers while collaboratin...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$134K - $221K *

Develop and lead a high-performing team of architects, driving customer success through effective management and delivery of Red Hat consulting solutions while aligning with strategic business objecti...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$90K - $120K *

Shape the future of veteran healthcare by overseeing transformative modernization projects, enhancing efficiency, and ensuring stakeholder collaboration for impactful service delivery...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $150K *

Unlock potential by leading the design and implementation of advanced digital systems in pharmaceutical manufacturing. Drive client satisfaction and project delivery while mentoring junior engineers a...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Drive impactful change by spearheading organizational change management strategies. Collaborate with stakeholders, enhance adoption of new processes, and ensure long-term success in complex IT environ...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$130K - $180K *

Empower the evolution of gateway solutions in telecommunications by leading the strategy, design, and lifecycle management, ensuring seamless integration and operational efficiency across diverse depl...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$130K - $180K *

Lead strategic engagements as a trusted advisor in complex enterprise sales, influencing C-suite decision-makers and driving success in high-stakes opportunities. Collaborate with sales teams to shape...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $130K *

Elevate your career as you manage the integration of advanced systems, ensuring secure access and optimal performance while collaborating with IT teams to enhance efficiency and streamline operations...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Empower innovation by developing advanced AI and automation solutions. Collaborate with teams to design, build, and support intelligent agents that address real business challenges and drive productiv...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Mission Systems Engineer do?question toggle

    A Mission Systems Engineer designs, maintains and enhances a variety of systems that are crucial for accomplishing a mission. This includes airborne systems, weapons systems, communication systems, and more.

  • How much can a Mission Systems Engineer earn?question toggle

    The salary for a Mission Systems Engineer can vary depending on experience and location, but jobs listed on Ladders pay $100,000 or more.

  • What types of companies hire Mission Systems Engineers?question toggle

    Industries such as Aerospace, Defense, IT, and Engineering Apps, among others, consistently need qualified Mission Systems Engineers.