Microsoft Systems Engineer Jobs

Discover Microsoft Systems Engineer jobs with organizations seeking experienced professionals to design, implement, and support enterprise technology environments. These roles bring together expertise in Microsoft platforms, infrastructure, cloud services, security, and end-user computing. Ladders features vetted professional opportunities paying $100,000 or more, including positions for engineers who can keep complex systems reliable, secure, and ready to scale.

What Does a Microsoft Systems Engineer Do?

Microsoft Systems Engineers plan and maintain the systems that organizations rely on every day. Depending on the employer, responsibilities may include administering Windows Server environments, managing Microsoft 365 and Azure services, supporting identity and access management, automating deployments, and resolving infrastructure issues. Engineers may also contribute to architecture decisions, disaster recovery planning, endpoint management, and technical documentation.

Skills and Qualifications Employers Value

Employers commonly look for hands-on experience with Microsoft technologies such as Windows Server, Active Directory or Microsoft Entra ID, Microsoft 365, Azure, and PowerShell. Knowledge of networking, virtualization, cloud operations, cybersecurity, and systems monitoring can strengthen an application. Clear communication and the ability to collaborate across IT, security, and business teams are also important, especially in senior and enterprise roles. Relevant Microsoft certifications may help demonstrate specialized expertise.

Career Paths and Opportunities

Microsoft Systems Engineers work across industries, including technology, finance, healthcare, manufacturing, and government. Career paths can lead to senior systems engineering, cloud engineering, infrastructure architecture, technical leadership, or IT management. The right opportunity depends on your platform expertise, preferred work environment, and whether you want to focus on cloud migration, enterprise operations, security, or automation.

Find Microsoft Systems Engineer Jobs on Ladders

Use Ladders to explore vetted Microsoft Systems Engineer opportunities paying $100,000 or more. Review job requirements, compare roles, and identify positions that align with your experience in Microsoft infrastructure and enterprise systems. New listings may be added regularly, so check back to find opportunities suited to your next career move.

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$100K - $120K *

Join a team that's dedicated to innovation and excellence, driving projects from concept to completion. Collaborate with cross-functional teams to enhance product development and ensure quality standa...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Join a team that's passionate about transforming complex scientific data into engaging communications. Collaborate with cross-functional experts to deliver high-quality medical content and strategies...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$168K - $200K *

Champion client relationships and lead diverse teams in life sciences, driving project success through strategic planning and scheduling expertise. Empower your career with mentorship and a focus on q...

Portland, ORRemote

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$66K - $102K *

Elevate your career by joining our consulting team to design and implement SAP PP/QM solutions, driving value for clients through innovative strategies and expert knowledge transfer in a dynamic, glob...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Lead the charge in managing projects from initiation to completion, ensuring alignment with business objectives. Collaborate with cross-functional teams to deliver results on time while effectively co...

Arkansas, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $118K *

Join a team that's dedicated to solving complex challenges in a dynamic environment. Collaborate with experts to drive innovation and enhance operational efficiency while contributing to impactful pro...

Ontario, CARemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$156K - $241K *

Oversee the management of demo environments, ensuring seamless integration and maintenance across departments. Collaborate with teams to deliver scalable technical architectures and optimize enterpris...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $120K *

Partner with us to enhance and optimize the Edifecs platform, ensuring efficient EDI transaction processing. Collaborate with cross-functional teams to troubleshoot and improve system performance in a...

Texas, USRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a team that's driving the execution of complex data center construction projects. Lead planning, manage resources, and optimize client service while ensuring quality and financial performance acr...

Texas, USRemote

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$125K - $172K *

Join a team that's dedicated to enhancing clinical practices in healthcare. As a strategic advisor, you'll collaborate with internal teams and customers, driving education and best practices while ens...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$138K - $165K *

Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $235K *

Join a team that's redefining business processes through digital transformation. Lead cross-functional initiatives, ensuring scalable and standardized practices that align with strategic goals while f...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Engage in innovative software development, collaborating with Agile teams to design, implement, and support solutions for population simulation. Drive project timelines and enhance application process...

Alexandria, VARemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $350K *

Build advanced inference systems to enhance RL research, optimizing throughput and enabling scalable model updates. Collaborate with researchers to balance efficiency and quality in cutting-edge AI ar...

San Francisco, CARemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $100K *

Elevate customer engagement by providing expert technical training and consulting. Collaborate with sales teams to enhance product understanding and drive growth through tailored demonstrations and su...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$119K - $161K *

Unlock potential by applying advanced thermal analysis techniques to solid rocket motor components. Collaborate with cross-disciplinary teams to drive technical excellence and ensure compliance with e...

New Market, ALRemote

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$72K - $138K *

Unlock your potential as an Intermediate I&C Engineer, designing and maintaining systems for nuclear and commercial projects. Collaborate with multi-discipline teams to ensure compliance with industry...

Oak Ridge, TNRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$125K - $150K *

Shape the future of product marketing by bridging product and go-to-market teams. Drive impactful messaging, enablement, and strategies that resonate with audiences, ensuring alignment in a fast-paced...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $128K *

Join a team that's dedicated to optimizing supply chain processes and ensuring timely delivery of quality goods. Manage vendor relationships, analyze inventory data, and lead a team to drive efficienc...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in managing complex biomanufacturing projects, coordinating with stakeholders, and supporting government initiatives to drive innovation in the biofabrication sector. Ensure project su...

Gaithersburg, MDRemote

Today

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Unlock your potential by managing complex DoD biomanufacturing projects. Collaborate with diverse stakeholders, oversee performance metrics, and develop impactful briefings for leadership in a dynamic...

Bethesda, MDRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Champion the future of energy by leading technical power system interconnection efforts. Drive complex analysis and team performance to optimize generation and transmission services, shaping strategic...

Austin, TXRemote

4 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform enterprise data integration by leading technical efforts, designing robust ETL/ELT pipelines, and ensuring data quality across complex systems. Drive excellence in data workflows and maintai...

Montgomery, ALRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $140K *

Transform your career by leading complex design change projects from inception to execution. Collaborate with cross-functional teams, manage substantial budgets, and drive innovation in a fast-paced e...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What does a Microsoft Systems Engineer do?question toggle

    A Microsoft Systems Engineer designs, operates, and improves technology environments built on Microsoft platforms. Common work includes managing Windows Server, Microsoft 365, Azure, identity services, security controls, automation, and infrastructure support.

  • What skills are needed for Microsoft Systems Engineer jobs?question toggle

    Commonly requested skills include Windows Server administration, Microsoft 365, Azure, Active Directory or Microsoft Entra ID, PowerShell, networking, virtualization, troubleshooting, and security fundamentals. Requirements vary by role and employer.

  • Do Microsoft Systems Engineers need certifications?question toggle

    Certifications are not required for every position, but relevant Microsoft credentials can help demonstrate platform knowledge. Employers may value certifications related to Azure, Microsoft 365, identity, security, or administration, alongside practical experience.

  • How much do Microsoft Systems Engineer jobs pay?question toggle

    Compensation varies by experience, location, industry, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, where available salary information and requirements are listed with each opportunity.

  • Where can I find Microsoft Systems Engineer jobs paying $100,000 or more?question toggle

    Explore Microsoft Systems Engineer listings on Ladders to find vetted professional opportunities with salaries of $100,000 or more. Compare job responsibilities and qualifications to identify roles that fit your background.