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Welcome to the Microsoft Systems Engineer Category

This category hosts premium job opportunities for Microsoft Systems Engineers. These are carefully vetted roles that pay …

1,000+ Microsoft Systems Engineer Jobs in Indianapolis, IN

$ Average salary: 139,150

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  • *Contingent * Senior Network Engineer 3

    $90K — $120K *Indianapolis, IN (Marion County)In-Person
    Optimize your career by leading network engineering initiatives. As a key technical expert, you will plan and develop robust network systems, resolve issues, and drive strategic goals to ensure an efficient and effective enterprise environment.
    Requirements: Bachelor's or 10+ yrs experience, TS/SCI clearance, Security+ certification.
  • Senior Proposal Manager

    $90K — $120K *US-AnywhereRemote in United States
    Champion the proposal development process, leading teams to deliver compelling, compliant responses for federal solicitations, while enhancing best practices and mentoring junior staff in a dynamic, remote environment.
    Requirements: Bachelor's degree, 7 years federal proposal experience, MS 365 proficiency.
  • Staff Software Engineer - Backend & AI Infra

    $120K — $160K *US-AnywhereRemote in United States
    Grow your career by architecting resilient, zero-downtime systems for real-time AI trading infrastructure, ensuring operational excellence in a high-stakes financial environment where reliability is paramount.
    Requirements: Extensive DevOps experience; strong Kubernetes and IaC skills; programming proficiency.
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    Principle, Enterprise Governance, Risk, and Compliance Specialist

    $103K — $181K *US-AnywhereRemote in United States
    Strategize enterprise risk initiatives, guiding cross-functional teams to facilitate informed decision-making and enhance organizational maturity in risk management practices through actionable insights and stakeholder collaboration.
    Requirements: Bachelor's degree; 7-10 years ERM experience; strong financial acumen required.
  • Senior Model Based System Engineer

    $89K — $148K *US-AnywhereRemote in United States
    Transform your career by leading model-based systems engineering efforts, guiding a team of modelers in architecting solutions for Navy systems. Leverage MBSE expertise to innovate and drive customer success in a collaborative, remote environment.
    Requirements: BS in Systems Eng or related, 5+ yrs experience, 4+ yrs with Cameo, leadership.
  • Director - QC Advanced Therapies LP2 Quality

    $123K — $180K *Lebanon, IN (Boone County)In-Person
    Transform quality control practices in a state-of-the-art gene therapy lab. Lead, mentor, and ensure compliance while managing daily operations and testing processes for innovative product delivery during start-up and ongoing operations.
    Requirements: Bachelor's in science, 5+ years cGMP QC experience, 3+ years leadership.
  • Solutions Management Manager

    $90K — $120K *Indianapolis, IN (Marion County)In-Person
    Lead the charge in implementing and managing innovative Cardiovascular and Radiology solutions, acting as a key contact for business partners while driving product enhancements based on analytics and best practices.
    Requirements: BA/BS and 5+ years of related experience, 2+ in solutions management.
  • Software Engineer, Platform (Developer Experience)

    $120K — $160K *US-AnywhereRemote in United States
    Drive innovation as a technical leader in Developer Experience, enhancing engineering productivity through tooling and frameworks. Collaborate with diverse teams to streamline workflows and empower developers to excel in delivering quality products.
    Requirements: 7+ years software engineering; 5+ years with containers; web framework expertise.
  • Sr. Global Project Manager

    $120K — $150K *US-AnywhereRemote in United States
    Lead complex, high-value projects globally, ensuring alignment with strategy and delivering on time and budget. Manage cross-functional collaboration, stakeholder relationships, and establish best-in-class project delivery practices.
    Requirements: BS in Engineering, 10+ years experience, PMP preferred, strong project management skills.
  • Senior Principal Consultant, Product Management

    $120K — $150K *US-AnywhereRemote
    Lead the charge in driving product strategy and execution for large-scale AI-driven solutions, partnering with cross-functional teams to meet customer needs and achieve significant business impact across diverse markets.
    Requirements: Bachelor's in tech, ITIL Certification, 10+ years in product management.
  • East Water Distribution Master Planning Lead

    $117K — $191K *Indianapolis, IN (Marion County)In-Person
    Transform complex water distribution systems through expert planning, design, and strategic leadership. Drive innovative solutions while ensuring quality and compliance, and mentor emerging engineers in environmental sustainability and public health.
    Requirements: Bachelor's in engineering, 10+ years experience, certified in SMS, leadership skills.
  • Senior Services Project Manager - Chemistry

    $104K — $173K *US-AnywhereRemote in United States
    Lead the charge in managing complex projects within the nuclear industry, overseeing engineering, procurement, and quality control to ensure safety, compliance, and customer satisfaction while fostering effective collaboration.
    Requirements: Bachelor's in Chemical Engineering, 8 years experience, 2 years in Nuclear.
  • Lead Mechanical Engineer 2 (Nuclear Plant Analysis) - Nuclear

    $134K — $205K *US-AnywhereRemote in United States
    Accelerate power generation through advanced engineering analysis and project management. Lead technical evaluations, mentor teams, and deliver solutions for nuclear power uprate projects, ensuring efficiency and client satisfaction while enhancing skills in thermodynamics and fluid mechanics.
    Requirements: BSME; 12+ years nuclear experience; report writing; MS Office proficiency.
  • Principal Consultant

    $145K — $190K *US-AnywhereRemote in United States
    Accelerate progress at the forefront of AI-enabled cloud data solutions. Lead strategic client engagements, mentor teams, and drive business success through advanced analytics, fostering trusted relationships and delivering excellence across multiple projects.
    Requirements: BA/BS in a quantitative field; 8+ years data analytics experience; SQL, Python.
  • Sales Engineer

    $80K — $110K *US-AnywhereRemote in United States
    Join a team that's driving sales and developing strategies for market growth by engaging with key clients and leveraging innovative solutions to enhance customer value and product adoption within the refining and chemical industries.
    Requirements: Bachelor’s in technical field, 2+ years sales experience, strong communication.
  • SR. SYSTEMS ENGINEER-TECHNOLOGY INTEGRATIONS

    $110K — $125K *US-AnywhereRemote
    Elevate your career by leading technology integration and migration projects, focusing on enterprise transformation and modernization during critical phases, ensuring seamless transitions and heightened data security across diverse platforms and environments.
    Requirements: Bachelor’s in IT/Computer Science; 5+ years in Windows/hybrid cloud; 3+ years in Microsoft 365.
  • Director, Device Manufacturing

    $120K — $160K *US-AnywhereRemote in United States
    Transform the future of medical device manufacturing by leading CMO operations, ensuring compliance, and driving efficiency in drug-device combination production. Leverage your expertise to elevate product delivery for clinical and commercial success.
    Requirements: Bachelor's in Engineering, 10+ years in medical device manufacturing.
  • Senior Product Manager

    $170K — $190K *US-AnywhereRemote in United States
    Shape the future of renewable energy by leading product strategy and execution. Collaborate with cross-functional teams to develop AI-driven tools that streamline operations, enhance customer experiences, and drive impactful clean energy projects.
    Requirements: 5+ years in product management, web-based software; familiarity with AI.
  • Site Technology Specialist

    $70K — $95K *US-AnywhereRemote in United States
    Join a team that's dedicated to providing essential technical support for clinical trials. You'll assist in implementing study procedures, coordinate data collection, and ensure proper documentation for technologies like MRI and nuclear medicine.
    Requirements: Associate degree required; MRI experience mandatory; clinical trial experience a plus.
  • Electrical Controls Engineer

    $70K — $95K *Columbus, IN (Bartholomew County)In-Person
    Design and implement innovative control systems for automation, ensuring efficiency and compliance. Collaborate with teams to troubleshoot and enhance existing setups, adapting to the latest technological advancements in industrial processes.
    Requirements: Bachelor's degree in Engineering, 2-5 years experience, PLC, HMI, SCADA expertise.
  • Site Technology Specialist

    $70K — $95K *US-AnywhereRemote in United States
    Champion innovative technology solutions in clinical trials, providing vital support and expertise to study sites and project teams, ensuring efficient data collection and adherence to procedural requirements across modalities like radiology and nuclear medicine.
    Requirements: 5+ years as a nuclear medicine technologist; RN/LPN or equivalent degree.
  • Senior Cloud Engineer

    $125K — $188K *US-AnywhereRemote in United States
    Engineer and build scalable enterprise applications and cloud-native solutions in Microsoft Azure, leveraging modern engineering practices and DevSecOps principles to enhance application performance and security across cloud environments.
    Requirements: Bachelor’s degree, 8–10 years experience, Java/Python expertise, Azure skills.
  • Associate Technical Program Manager

    $90K — $175K *US-AnywhereRemote in United States
    Drive the charge in managing small technical projects that ensure successful delivery of cloud operations initiatives, collaborating cross-functionally with Engineering, Customer Success, and internal teams to achieve business goals.
    Requirements: Bachelor's in IT/Computer Science; 1+ years project management; Cloud experience.
  • Agentic AI Engineer

    $120K — $160K *US-AnywhereRemote in United States
    Transform enterprise AI by shaping its technical direction and architecture. As a founding engineer, you’ll lead the build of agentic AI systems while enabling teams across the company to adopt innovative solutions effectively.
    Requirements: 7+ years software engineering; expertise in Python, LLMs, systems design.
  • Service Engineer, Automation

    $70K — $95K *US-AnywhereRemote
    Join a team that's dedicated to enhancing automation solutions through troubleshooting, programming, and customer collaboration. Leverage your skills to improve machinery performance and ensure seamless operations in diverse manufacturing environments.
    Requirements: A.S. degree or equivalent in related field; 3+ years programming experience.
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*Contingent * Senior Network Engineer 3

Company Name
$90K — $120K *
Indianapolis, IN 46227
In-Person
Telecommunications & Hardware
8 - 10 years of experience
Job Description

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FAQ About Microsoft Systems Engineer Jobs in Indianapolis, IN

What does a Microsoft Systems Engineer do?

A Microsoft Systems Engineer manages, troubleshoots, and improves computer systems based on Microsoft products and technologies. They ensure system efficiency and handle problems as they emerge.

What skills are required for a Microsoft Systems Engineer job?

A Microsoft Systems Engineer needs strong proficiency with Microsoft products, problem-solving skills, knowledge of system engineering, and often relevant certifications like the Microsoft Certified: Azure Solutions Architect.

What kinds of companies hire Microsoft Systems Engineers?

Companies across a multitude of industries hire Microsoft Systems Engineers. This includes tech firms, financial institutions, healthcare providers, government agencies, educational institutions, and many others.