Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

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$150K - $280K *

Elevate AI and autonomy technologies from concept to production-ready solutions. Collaborate across teams to drive commercialization and product strategy while ensuring effective implementation and in...

Lone Tree, CORemote

1 month ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $135K *

Lead the charge in developing and implementing global safety standards and compliance initiatives. Collaborate with cross-functional teams to foster a proactive safety culture, ensuring the health and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$105K - $150K *

Elevate the future of high-voltage systems by leading design and delivery of protection and control solutions for substations, mentoring junior engineers, and ensuring compliance with industry standar...

North Olmsted, OHRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $223K *

Drive incident response excellence by leading major cybersecurity incidents, maturing processes, and supporting cross-functional teams. Own readiness and resilience while fostering a culture of collab...

New York, NYRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$108K - $137K *

Empower operations by ensuring data integrity for market systems. Partner to verify service reservations and regulatory compliance while providing analytical insights to enhance stakeholder engagement...

Little Rock, ARRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$163K - $218K *

Shape the future of information security by maintaining and advancing our ISMS while ensuring ISO 27001 and SOC 2 Type 2 compliance. Drive collaborations across teams to build effective processes and...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Champion our IT infrastructure by automating identity and device management. In this dynamic role, you'll implement innovative security measures while ensuring operational efficiency in a cutting-edge...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Accelerate business growth by leading proposal management efforts, ensuring compliance and responsiveness while guiding teams towards developing compelling proposals across various sectors. Drive exce...

Rockville, MDRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$181K - $241K *

Take ownership of enterprise-wide risk management strategies, guiding executive leadership in navigating operational, financial, and construction risks. Collaborate across functions to enhance risk pr...

RemoteRemote

5 days ago

  •   11 - 15 years exp.  •   Energy & Utilities

$119K - $145K *

Advance supply chain efficiency by optimizing operations, collaborating cross-functionally, and implementing innovative solutions. Engage with stakeholders to analyze performance metrics and support k...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$191K - $293K *

Lead the charge in providing strategic employment law counsel, guiding the People team and stakeholders on compliance, investigations, and policy development to foster a supportive workplace while mit...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Optimize rebate operations and drive continuous improvements as you manage the full lifecycle of contracts, ensuring accurate calculations and compliance while collaborating cross-functionally to enha...

Miami Lakes, FLRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $190K *

Innovate solutions by leading the strategy and implementation of AI and automation in critical facilities operations, translating operational challenges into digital advancements to enhance safety, ef...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $150K *

Unlock potential by overseeing project operations and client relationships, driving growth through strategic partnerships and best practices. Lead teams to achieve business goals while ensuring high s...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$106K - $160K *

Innovate project management strategies for design and construction initiatives, ensuring timely delivery and budget adherence. Collaborate with stakeholders to enhance facility development and maintai...

Sacramento, CARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$240K - $300K *

Empower strategic partnerships across the Eastern U.S. to drive revenue growth. Build and manage a partner-sourced pipeline, enhance customer engagement, and accelerate deal closures through collabora...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$252K - $321K *

Drive hardware security strategy across Cisco's extensive product portfolio, establishing secure-by-design standards and collaborating with industry leaders to shape the future of embedded security in...

North Carolina, USRemote

1 month ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$130K - $140K *

Shape the future of IT operations by bridging infrastructure and development teams. Utilize your expertise in ServiceNow ITOM to analyze requirements, streamline processes, and enhance operational eff...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$89K - $148K *

Elevate financial management and audit remediation efforts for DoD clients, leveraging expertise in accounting, internal controls, and compliance to drive strategic improvements and ensure adherence t...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$181K - $301K *

Transform your career by leading a global cyber defense team, driving proactive strategies to mitigate risks and enhance security across diverse environments. Collaborate with cross-functional teams t...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Advance the SAP-to-NetSuite migration by implementing, testing, and optimizing the new ERP system. Collaborate with teams to ensure user training and support for a seamless transition and continuous i...

CanadaRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$108K - $148K *

Join a team that's enhancing data governance. Leverage your expertise to guide cross-functional teams in applying policies and standards, maintain data accuracy, and champion a strong data culture wit...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$128K - $218K *

Elevate customer acquisition efforts by leveraging your expertise in Compliance, FinTech, and RegTech. Collaborate with Sales and Solutions Architects to translate regulatory challenges into impactful...

Alabama, USRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Innovate secure network solutions by engineering and supporting robust infrastructure. Collaborate with cross-functional teams to enhance security technologies, ensuring reliable connectivity and comp...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$161K - $299K *

Optimize critical materials supply chains by collaborating across teams to identify risks, develop new sources, and enhance resilience. Drive initiatives to improve supplier capabilities and mitigate...

Grand Prairie, TXRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.