Welcome to Information Systems Security Officer (ISSO) Jobs

As an Information Systems Security Officer (ISSO), you play a critical role in protecting an organization's information system. Discover opportunities that pay over $100k, exclusively available on Ladders.

Job responsibilities

As an ISSO, your responsibilities can include ensuring system security, conducting regular checks, and implementing the organization's security policy.

Skills Needed

Successful ISSOs often have strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

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$100K - $125K *

Lead the charge in executing complex healthcare software implementations, managing multiple projects while ensuring financial performance and client satisfaction. Drive process improvements and mentor...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$70K - $117K *

Innovate cutting-edge shipboard electronic systems to enhance maritime operations. Collaborate with teams to support Military Sealift Command through design, engineering, and technical analysis on spe...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $130K *

Optimize compliance and support quality standards by managing CMO interactions, ensuring accurate submissions, and addressing license non-compliances effectively alongside cross-functional teams. Driv...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$81K - $123K *

Optimize clinical application support to enhance patient care efficiency, ensuring seamless integration of technology across healthcare systems while collaborating with IT teams for implementation and...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $120K *

Deliver innovative integration solutions by architecting, leading, and executing technical strategies that enhance client operations and enable efficient business processes, while collaborating with s...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$124K - $170K *

Join a team that’s advancing healthcare technology by ensuring the highest standards of software quality throughout the medical device life cycle. Lead assurance activities and compliance efforts to e...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $251K *

Shape the future of global trade by leading SAP GTS configurations, ensuring seamless implementation and compliance. Collaborate with cross-functional teams to harmonize processes and elevate operatio...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$90K - $120K *

Analyze and develop electronic Case Report Forms (eCRFs) for over 100 clinical trials, ensuring data quality and alignment with research protocols. Collaborate with study teams and manage comprehensiv...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Join a team that's shaping the future of software development! Inspire innovation by leading projects and delivering high-quality software solutions using cutting-edge Microsoft technologies in a coll...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $175K *

Join a team that's redefining partnership success as you enable our technical ecosystem. You'll collaborate with top-tier partners, driving integration innovation while managing key revenue streams an...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $200K *

Lead the charge in delivering high-quality primary care services and ensuring operational excellence within the VISN 15 Clinical Resource Hub. This remote role involves leadership, program management...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $111K *

Transform data into actionable insights by driving analytics across teams, enhancing sales operations. Collaborate with departments to optimize reporting and forecasting models, ensuring alignment fro...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$75K - $95K *

Engage with key stakeholders to gather requirements, analyze processes, and support cost-benefit assessments for Veterans Affairs IT projects, contributing to effective documentation and operational i...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $120K *

Drive strategic vendor relationships by managing procurement, performance, and compliance. Collaborate with diverse stakeholders to optimize vendor processes and contracts, ensuring alignment with bus...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $126K *

Lead the charge in overseeing MICRO's infrastructure strategy, providing technical direction and daily management across diverse systems, ensuring stability and compliance while driving operational re...

US-AnywhereRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$155K - $240K *

Join a dynamic team as you lead high-performance operations, supporting our rapidly growing partner ecosystem. Drive strategic initiatives, optimize processes, and enhance collaboration while making a...

US-AnywhereRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $150K *

Shape the future of remote sales by leading team performance, closing deals, and cultivating talent within an engaging environment focused on growth and success, all while managing your own book of in...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$90K - $150K *

Transform your career by leading a virtual sales team, managing inbound leads, and coaching others in a flexible remote environment. Drive success through innovation and strategic execution, while ear...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$130K - $180K *

Lead enterprise-level AI architecture initiatives, designing advanced multi-agent systems and orchestrating AI/ML strategies across cloud and open-source platforms to drive innovation and maximize bus...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $180K *

Shape the future of enterprise AI systems by designing and delivering multi-agent orchestration pipelines, optimizing AI/ML integration, and advising C-suite executives on strategy and ROI...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$112K - $125K *

Shape product strategy by collaborating with stakeholders to define features, prioritize backlogs, and deliver innovative solutions that meet business objectives. Ensure alignment with development tea...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $160K *

Lead the charge in overseeing critical federal projects, managing cross-functional teams to ensure service delivery, compliance, and customer satisfaction; a key role requiring strategic leadership an...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$180K - $200K *

Empower enterprise growth through strategic sales engineering. Support and collaborate with account executives, navigate complex sales, and enhance customer experience with innovative technology solut...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Transform the healthcare infrastructure for Veterans by leading modernization initiatives. Collaborate with diverse teams to design secure, scalable solutions and ensure compliance with federal standa...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $105K *

Transform our approach to healthcare project management by driving initiatives and enhancements that ensure successful delivery while fostering collaboration across teams and maintaining high standard...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is the role of an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is responsible for ensuring the confidentiality and integrity of an organization's information system. They implement the organization's IT security policies and conduct regular checks and audits.

  • What skills do you need for ISSO jobs?question toggle

    ISSOs need strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

  • What kind of ISSO jobs are available on Ladders?question toggle

    Ladders offers a variety of high-paying ISSO jobs from reputable companies that value your skills and experience.