Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
$107K - $195K *
Unlock potential by designing and developing innovative digital solutions that enhance mission efficiency and data visibility for the U.S. Coast Guard. Collaborate with users to create impactful appli...
1 week ago
$120K - $200K *
Transform backend services and REST APIs in a collaborative environment. Leverage your software engineering skills to support cyber training initiatives, utilizing modern technologies and cloud infras...
1 week ago
$250K - $350K *
Empower enterprise clients by leading executive technology strategy, driving transformation initiatives that connect business priorities with major technology shifts, and building long-term, trust-bas...
4 weeks ago
Service Design and Delivery Lead
$157K - $298K *
Unlock potential by orchestrating cross-functional teams to design scalable enterprise services that enhance customer experiences and drive business value through innovative service design and systems...
1 week ago
$120K - $160K *
Unlock potential by leading complex federal contract negotiations and management. Collaborate with cross-functional teams, ensuring compliance and driving strategic solutions to support business growt...
Reposted 1 week ago
$125K - $150K *
Oversee large-scale Federal contracts, ensuring compliance and strategic alignment. Leverage expertise in negotiation and federal regulations to enhance program execution, drive business growth, and e...
Reposted 1 week ago
Mgr, Customer Success Engineering
$120K - $145K *
Lead the charge in driving customer success and product adoption by managing a team of Scale and Optimize Engineers. Foster innovation, enhance customer relationships, and ensure operational excellenc...
2 weeks ago
Manager, Database Administration
$139K - $174K *
Unlock your potential by leading a dynamic database operations team. With over a decade of experience, guide strategic database infrastructure initiatives, ensure system reliability, and foster a cult...
Reposted 3 weeks ago
AVP Technical Sales Leader - Identity COE
$194K - $320K *
Empower a high-performing team as you lead the Identity & Access Security COE, driving technical wins and strategic engagement with C-level executives while fostering collaboration between Sales and P...
2 weeks ago
Senior Learning Systems Administrator
$90K - $110K *
Champion the optimization of learning systems by managing Workday Learning, providing enterprise support, and leading technology projects. Collaborate with stakeholders to enhance governance, complian...
1 week ago
Technical Counselor, Data and Ai
$150K - $180K *
Empower Data and AI Leaders by providing expert technical counsel, optimizing decision-making, and enhancing client success through tailored strategies and proactive thought leadership in a dynamic, c...
3 weeks ago
Regulatory Publishing Technical Consultant (Regulatory Systems)
$100K - $120K *
Unlock your potential as a Technical Consultant, providing expert support in regulatory publishing systems and document management. Collaborate with teams and clients to troubleshoot issues, enhance s...
1 week ago
$75K - $92K *
Transform research funding processes by managing grant activities, ensuring compliance, and providing expert guidance to departments. Collaborate with teams to develop budgets and navigate proposal su...
Yesterday
$104K - $163K *
Shape the future of IT project management by leading cross-functional teams to deliver impactful technology solutions on time and within scope, while enhancing processes and ensuring effective stakeho...
Reposted today
$110K - $130K *
Unlock potential by providing expert radar engineering support for FAA modernization, enhancing technical solutions and ensuring effective integration and deployment within the National Airspace Syste...
Reposted today
$279K - $342K *
Shape the future of security by leading a multidisciplinary team to enhance product, corporate, and information security. Drive strategic initiatives, foster collaboration, and ensure compliance while...
4 days ago
Hardware Integration Project Manager (Facilities & Equipment) - EV Construction Management
$140K - $160K *
Unlock potential by leading hardware integration projects from prototype to deployment. Collaborate with cross-functional teams to ensure product viability in real-world environments while managing ri...
2 days ago
Senior Middleware Administrator
$110K - $130K *
Lead the charge in optimizing enterprise middleware platforms through effective administration, automation, and security management, ensuring high availability and compliance while enhancing operation...
1 week ago
$80K - $95K *
Empower our analyst relations program by managing evaluations, timelines, and coordination. Collaborate with stakeholders to ensure accurate, timely engagement and support market insights for strategi...
Reposted 3 weeks ago
Senior Vice President, Client Implementations, Revenue Cycle (REMOTE)
$175K - $210K *
Unlock potential by leading implementation strategies to enhance client onboarding and satisfaction. Drive efficiencies across systems, manage a dedicated team, and collaborate with departments to ens...
4 weeks ago
Senior Sales Executive - State & Local Government
$140K - $180K *
Champion growth by leveraging your consultative sales expertise to secure contracts and enhance client relationships in the public sector, specifically within Medicaid and Human Services programs. Dri...
1 week ago
Senior Regulatory Affairs Specialist (Remote - United States)
$124K - $170K *
Champion regulatory strategies to accelerate product approvals and compliance. Lead a dynamic team in supporting innovative medical devices, ensuring alignment with global regulations while fostering...
3 days ago
IBR Policy and Content Development Analyst
$85K - $110K *
Shape the future of healthcare payment integrity by developing and enhancing clinical and coding solutions. Collaborate with cross-functional teams to ensure compliance with coding standards and optim...
1 week ago
Information Systems Operations Manager
$100K - $120K *
Lead the charge in optimizing our Information Systems operations, ensuring seamless support for hardware and software. Manage a dedicated team while enhancing productivity through AI tools and maintai...
Today
Senior Consultant - State Government IT IV&V
$90K - $130K *
Pioneer innovative solutions for state government clients by leading IV&V projects, providing expert guidance on system implementations, and ensuring project success through effective communication an...
1 week ago
What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.