Welcome to Information Systems Security Officer (ISSO) Jobs

As an Information Systems Security Officer (ISSO), you play a critical role in protecting an organization's information system. Discover opportunities that pay over $100k, exclusively available on Ladders.

Job responsibilities

As an ISSO, your responsibilities can include ensuring system security, conducting regular checks, and implementing the organization's security policy.

Skills Needed

Successful ISSOs often have strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

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Compensation
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$172K - $232K *

Lead global GxP quality incident management processes, ensuring compliance and safety while fostering cross-functional collaboration for effective quality risk resolution and continuous improvement in...

US-AnywhereRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $220K *

Optimize security infrastructure by automating endpoint management and configuration through code, enhancing operational efficiency, and ensuring robust compliance across diverse platforms in a dynami...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $200K *

Unlock potential by leading enterprise sales strategies in cloud security, focusing on cloud-native solutions. Drive engagement with CISOs and DevSecOps leads to position innovative security offerings...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $100K *

Contribute to IT excellence by managing helpdesk support, enhancing documentation standards, and driving Tier 2 systems administration across diverse SaaS platforms, fostering a collaborative environm...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$115K - $145K *

Optimize security and IT operations, supporting diverse teams and managing requests while ensuring efficient access control and incident responses. Collaborate in a remote-first environment dedicated...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$146K - $271K *

Contribute to strategic data protection solutions by leveraging expertise in Microsoft technologies, driving growth and collaboration, while advising field teams on complex sales, delivering tailored...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $180K *

Champion seamless customer authentication and authorization experiences by leveraging advanced CIAM solutions. Collaborate with cross-functional teams to enhance identity security and streamline user...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Empower digital transformation by architecting innovative AI solutions that integrate Salesforce, Oracle, and SAP technologies. Collaborate with stakeholders to deliver scalable, secure platforms meet...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $120K *

Join a team that's optimizing clinical trial operations. Manage site performance, oversee monitoring activities, and ensure compliance with standards while fostering relationships in an evolving envir...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Transform the proposal landscape as you manage high-stakes public-sector submissions. Own the compliance and lifecycle oversight while collaborating with cross-functional teams to produce compelling p...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$70K - $95K *

Lead public-sector proposal efforts, ensuring compliance and quality in all submissions. Collaborate with stakeholders to craft compelling proposals while managing multiple projects under tight deadli...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $120K *

Join our team to bridge operational needs with system capabilities, driving configuration, testing, and continuous improvement for Manhattan Active WMS across diverse fulfillment networks...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$90K - $120K *

Engage as a Level 2 Engineer focusing on complex data integration and automated document generation, ensuring system flow integrity while delivering effective solutions through collaboration and metic...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $199K *

Innovate the support operating model by leveraging automation and agentic AI to transform customer issue resolution, enhancing efficiency and scalability without proportional headcount growth...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$109K - $149K *

Join a team that drives impactful process improvements with a focus on cost reduction and efficiency. Collaborate with leaders across divisions to deliver data-driven solutions that enhance operations...

US-AnywhereRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$134K - $205K *

Lead the charge in modernizing nuclear power plants through innovative control technologies, managing projects that enhance efficiency and performance while collaborating with cross-disciplinary teams...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Energy & Utilities

$120K - $160K *

Architect innovative data pipelines for the US Space Force, integrating complex datasets and delivering insightful analysis that enhances satellite communication capabilities for mission-critical oper...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$140K - $160K *

Champion data security by designing and implementing comprehensive controls to protect sensitive information across diverse environments, addressing emerging risks related to generative AI and large l...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $160K *

Partner with us to architect innovative solutions for mainframe infrastructure, leveraging your extensive technical expertise in Broadcom's suite of products. Shape the future of our clients' operatio...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $120K *

Grow your career with us by leading the sales strategy for our cloud solutions. As a pivotal member of our team, you’ll engage with C-level executives, manage global pipelines, and drive complex deals...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$160K - $185K *

Unlock the potential of data and AI by leading cross-functional teams to enhance strategies, processes, and solutions essential for meeting enterprise needs and driving innovation for clients...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$160K - $190K *

Lead the development of complex proposals, collaborating with cross-functional teams to drive strategic initiatives and craft winning submissions that align with customer needs and business goals in a...

US-AnywhereRemote

6 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$130K - $175K *

Lead the design and implementation of advanced BI solutions to enhance data-driven decision-making and optimize financial reporting processes across government projects...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

$75K - $95K *

Tackle Medicare/Medicaid Program Integrity challenges by developing educational materials, ensuring compliance, and guiding stakeholders on fraud, waste, and abuse strategies to enhance the integrity...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $175K *

Champion federal budget analysis by driving compliance, execution, and insights. Support leadership in strategic resource decisions while ensuring efficiency and accuracy in financial data management...

US-AnywhereRemote

5 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What is the role of an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is responsible for ensuring the confidentiality and integrity of an organization's information system. They implement the organization's IT security policies and conduct regular checks and audits.

  • What skills do you need for ISSO jobs?question toggle

    ISSOs need strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

  • What kind of ISSO jobs are available on Ladders?question toggle

    Ladders offers a variety of high-paying ISSO jobs from reputable companies that value your skills and experience.