Welcome to Information Systems Security Officer (ISSO) Jobs

As an Information Systems Security Officer (ISSO), you play a critical role in protecting an organization's information system. Discover opportunities that pay over $100k, exclusively available on Ladders.

Job responsibilities

As an ISSO, your responsibilities can include ensuring system security, conducting regular checks, and implementing the organization's security policy.

Skills Needed

Successful ISSOs often have strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

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$100K - $170K *

Innovate with cutting-edge Android technology to enhance our RFID app. Collaborate closely with engineering teams to optimize performance, streamline features, and ensure a robust experience on rugged...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$80K - $95K *

Unlock potential by supporting quality control systems and processes in manufacturing. Collaborate with cross-functional teams to enhance product quality, streamline defect management, and drive actio...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$86K - $138K *

Shape the future of AI integration by designing, developing, and maintaining a cutting-edge decision-support platform. Collaborate across teams while connecting AI agents with external data sources an...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$83K - $135K *

Grow your expertise by developing innovative security controls to protect critical assets in a dynamic environment. Collaborate with teams to implement cutting-edge technologies and security solutions...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $130K *

Lead the charge in transforming technical support through deep diagnosis and automation. Collaborate with teams to enhance agentic systems, resolving high-severity issues while building scalable solut...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$177K - $242K *

Drive patient access initiatives by leading affordability programs and vendor management while collaborating across teams to enhance patient solutions and ensure operational excellence in a fully remo...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion robust client relationships and oversee Veeva Vault managed services, ensuring project success through effective scheduling, budget management, and hands-on technical expertise while leading...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $125K *

Lead the charge in managing medical policy releases, ensuring compliance, quality assurance, and stakeholder communication to optimize deployment in a dynamic healthcare environment...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $176K *

Shape the future of cybersecurity management by leading a dedicated team to triage, prioritize, and escalate security requests and incidents, ensuring effective communication and collaboration across...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Drive the strategic technical partnership landscape by managing integrations and communication to enhance the product ecosystem. Independently evaluate technical requirements, support effective partne...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $171K *

Lead and develop a transformative cybersecurity function, driving enterprise initiatives while collaborating across diverse business areas to enhance security and resilience in a complex environment...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Drive innovation in SharePoint solutions, leading a team to enhance federal client operations through effective site design, development, and support while ensuring compliance and operational excellen...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $222K *

Lead and manage commissioning activities for power generation projects, ensuring optimal performance and safety through direct oversight, team collaboration, and adherence to regulatory standards acro...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

$83K - $114K *

Manage diverse construction projects by leading teams, ensuring quality and safety, and maintaining client relationships while navigating various environments for timely and budget-conscious delivery...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$130K - $185K *

Unlock potential by joining as a Blue Team Security Engineer, where you'll assess third-party security, automate tools, and drive incident response to enhance organizational safety while collaborating...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $95K *

Champion a dynamic credentialing program while leading operational excellence through innovative technology and regulatory compliance, ensuring the integrity of verification processes and aligning wit...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $161K *

Transform security practices by leading application testing initiatives, collaborating with teams to enhance security measures, and ensuring compliance with industry standards while fostering a cultur...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Champion exceptional service as you resolve complex partner escalations, optimize key workflows, and drive improvements in a fast-paced environment. Collaborate across teams to enhance partner experie...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$226K - $376K *

Join a team that's delivering innovative Microsoft solutions, managing multiple projects from inception to deployment, and enhancing client satisfaction through strong leadership and collaboration acr...

US-AnywhereRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$79K - $105K *

Join a team that's dedicated to ensuring compliance through thorough audits and analysis. Your role centers on evaluating clinical operations against regulatory standards, fostering continuous improve...

US-AnywhereRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $226K *

Lead the charge in enhancing detection capabilities within our Rapid Response Team. Drive innovative solutions for emerging threats, fostering team growth while providing hands-on technical leadership...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a team that's transforming IT operations through effective configuration and change management, ensuring data integrity and compliance in a dynamic global network environment with ITIL best pract...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Drive cutting-edge AI-native software delivery by architecting the DevX platform. Guide engineering teams in integrating developer capabilities, ensuring security, and optimizing workflows through inn...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Innovate security solutions at scale by collaborating with engineering teams, leading initiatives, and mentoring engineers to enhance product security and application safety throughout the software de...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Build innovative Power Platform solutions to enhance government IT operations. Collaborate with stakeholders to automate processes and streamline workflows while managing the full software development...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What is the role of an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is responsible for ensuring the confidentiality and integrity of an organization's information system. They implement the organization's IT security policies and conduct regular checks and audits.

  • What skills do you need for ISSO jobs?question toggle

    ISSOs need strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

  • What kind of ISSO jobs are available on Ladders?question toggle

    Ladders offers a variety of high-paying ISSO jobs from reputable companies that value your skills and experience.