Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
Change Management Lead - R&D Advisory
$100K - $120K *
Help us drive change management initiatives in life sciences R&D, enhancing efficiency and effectiveness across research, clinical, and regulatory operations while leading stakeholder engagement and a...
1 week ago
Manager - CX Microsoft Engineering
$150K - $225K *
Lead the charge in mentoring a high-performing software development team, driving technical vision and process improvements while ensuring alignment with organizational goals and fostering collaborati...
Today
$92K - $166K *
Drive satellite analysis and intelligence production by researching, tracking, and assessing satellite activity. Collaborate with partners to identify threats and deliver timely insights that support...
3 weeks ago
Network Administrator (IT Network & Telecoms - Journey)
$85K - $115K *
Join us in empowering Washington's environmental efforts by managing and optimizing our network infrastructure. This role combines technical expertise with project management to ensure seamless connec...
1 week ago
Account Executive - Space (FedS171B)
$145K - $185K *
Join a team that's transforming the Space ecosystem by driving strategic acquisition efforts. You'll lead capture initiatives, engage stakeholders, and develop win strategies that bolster national sec...
Reposted 3 weeks ago
Senior Optical Transport Implementation Engineer - Pub Sec
$93K - $124K *
Unlock potential by joining a team focused on advanced Tier II support for network devices in a fiber optic transport network, ensuring operational excellence and 100% service availability across mult...
Reposted 1 week ago
Senior Telecommunications Engineering Specialist
$89K - $148K *
Join a team that's dedicated to delivering innovative telecommunications solutions. Lead the design and engineering of complex systems, ensuring compliance with security standards while optimizing per...
2 weeks ago
Identity and Access Management Engineer (Authentication)
$92K - $130K *
Lead the charge in designing and implementing secure IAM authentication solutions that enhance user experience while ensuring security. Collaborate with cross-functional teams to troubleshoot issues a...
1 month ago
Manager - Cloud Management Services
$165K - $185K *
Shape the future of cloud management by leading a dynamic team in delivering VMware by Broadcom solutions. Drive technical excellence, mentor talent, and ensure high-quality service delivery for enter...
3 weeks ago
$132K - $251K *
Drive enterprise-wide DMSMS management by establishing standardized processes and frameworks to mitigate supplier risks and enhance operational stability, ensuring compliance with government standards...
3 days ago
Associate Systems Engineer, Data Management
$95K - $115K *
Join a team that's redefining data management solutions. Leverage your expertise in cloud platforms and analytics to support sales teams, drive customer success, and implement innovative data solution...
3 days ago
$148K - $164K *
Optimize cloud security operations by monitoring and securing Azure and AWS environments. Collaborate with teams to integrate security into deployment pipelines and ensure compliance with industry sta...
Today
Senior Technical Success Manager
$143K - $205K *
Engage with customers to drive adoption and value realization of solutions, managing relationships and risks while supporting highly regulated environments. Collaborate with technical stakeholders to...
1 week ago
Oracle eBusiness Suite Developer.
$135K - $160K *
Champion the development and management of Oracle eBusiness Suite solutions, leading critical projects and resolving advanced technical issues while ensuring compliance with government policies and en...
1 week ago
Instrumentation & Controls (I&C) Maintenance Instructor / Technical Leader I
$115K - $130K *
Deliver high-quality training for I&C technicians, ensuring comprehension and performance tracking. Collaborate with teams to enhance training materials and support continuous improvement in a virtual...
2 weeks ago
$131K - $237K *
Lead the charge in designing and deploying innovative cloud solutions, enhancing user experiences while modernizing the DoD environment through strategic cloud migrations and security best practices...
2 weeks ago
$160K - $201K *
Lead the charge in shaping and evolving a global web ecosystem, overseeing strategy, operations, and governance to deliver high-performing digital experiences that drive engagement and business growth...
1 week ago
Director, Health & Life Sciences Research/Communities - Remote
$125K - $140K *
Lead transformative healthcare initiatives by fostering client relationships, driving impactful research, and developing high-performance teams to achieve strategic goals and business growth...
Today
Senior Network Security Engineer - Palo Alto (Remote)
$170K - $180K *
Optimize enterprise network security with hands-on design, implementation, and mentoring. Lead complex projects, drive client success, and contribute to evolving tech standards while cultivating relat...
3 weeks ago
Technical EDI Analyst (Remote)
$64K - $128K *
Empower your career by delivering data analysis on EDI transactions, facilitating tool implementations, and fostering cross-department collaboration to enhance system performance and meet organization...
4 weeks ago
$131K - $237K *
Drive enterprise cloud infrastructure design and optimization, ensuring high availability, security, and scalability. Collaborate with diverse teams in a dynamic environment to enhance cloud adoption...
Reposted 3 weeks ago
Senior Business Systems Analyst - FOSS/ SBOM (Remote)
$111K - $170K *
Lead the establishment and management of an enterprise governance framework for Free and Open Source Software (FOSS) and Software Bills of Materials (SBOMs), ensuring compliance and risk management ac...
1 week ago
Director of Services - US West
$150K - $200K *
Engage in leading a dynamic team dedicated to delivering top-notch offensive security engagements, ensuring delivery quality and client satisfaction, while collaborating with sales to expand accounts...
Reposted 2 weeks ago
Associate Information Security Engineer
$68K - $105K *
Shape the future of Information Security by assisting in the design, development, and implementation of ISRM Infrastructure systems. Collaborate with teams to ensure compliance, analyze systems perfor...
Reposted 2 weeks ago
Senior Director Analyst - Digital Workplace Infrastructure and Operations
$172K - $202K *
Join a dynamic team as a Senior Director Analyst, leveraging your expertise to guide senior IT executives in navigating digital workplace strategies. Deliver actionable insights that align technology...
Today
What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.