Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

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1
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$165K - $175K *

Deliver seamless integration of security operations by managing vendor teams, mentoring embedded employees, and aligning strategies with client objectives while fostering communication and operational...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Technical Services

$75K - $158K *

Unlock potential by serving as a key Oracle P2P Business Analyst, driving solution analysis, implementation, and collaboration with cross-functional teams in a dynamic, mission-focused environment...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $116K *

Empower your career by leading ServiceNow ITSM initiatives, enhancing workflows, and collaborating with diverse teams. Drive improvements to user support and organizational knowledge while utilizing y...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$132K - $251K *

Champion innovation in software development as a DevSecOps Software Lead, driving the design and implementation of advanced pipelines. Collaborate with teams to enhance efficiency and foster a culture...

Annapolis, MDRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$153K - $242K *

Shape the future of cybersecurity by developing innovative architectures and strategies that integrate AI and emerging technologies, enhancing security capabilities across multiple domains while colla...

CanadaRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $135K *

Drive your career in cyber claims by managing primary first-party claims. Collaborate with teams and external vendors to ensure optimal outcomes while receiving mentorship and support in a fully remot...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$82K - $110K *

Join a dynamic team dedicated to enhancing workplace safety and health. This role involves conducting investigations, inspections, and collaborating with various agencies to ensure compliance and impr...

Snohomish, WARemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Shape the future of enterprise Linux and Unix operations, leading a team to deliver and modernize infrastructure services across various platforms while ensuring performance, security, and client sati...

Connecticut, USRemote

1 month ago

  •   8 - 10 years exp.  •   Information Technology

$72K - $122K *

Lead incident response efforts within a dynamic Cyber Incident Response Team, utilizing advanced security tools to monitor and protect Judiciary technology. Collaborate on special projects and ensure...

Trenton, NJRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Unlock potential by leading strategic growth initiatives in the Public Sector. As a trusted advisor, you'll enhance client relationships and drive adoption of innovative health solutions, ensuring mea...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $149K *

Lead the charge in streamlining EDI 834 processes and enhancing enrollment operations. Collaborate with cross-functional teams to optimize data accuracy and customer satisfaction in this vital remote...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Accelerate progress at the intersection of autonomous systems and cloud-native technologies, driving integration and architecture solutions for defense and commercial sectors. Engage with stakeholders...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Elevate project execution by leading a team of Control Technicians, ensuring quality, timely completion, and effective communication across all stakeholders while providing technical support and mento...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$187K - $224K *

Lead the charge in managing complex technical solutions across multiple workstreams, ensuring seamless integration and delivery for a high-stakes federal program. Drive risk management and stakeholder...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$160K - $200K *

Unlock potential by guiding mid-size companies through IT transformation, ensuring alignment with business goals while enhancing operational efficiency and compliance in the healthcare sector...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Oversee acquisition program management activities, coordinating teams and processes to enhance operational efficiency and support senior government stakeholders in a dynamic environment...

Bethesda, MDRemote

Today

  •   Less than 5 years exp.  •   Business Services

$110K - $150K *

Take ownership of the SAP Concur platform, ensuring efficient travel and expense processes. Collaborate with cross-functional teams to enhance system functionality, resolve issues, and support complia...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Partner with us to drive innovative security solutions, engaging with customers and partners to address their unique challenges. Leverage your expertise in pre-sales and engineering to enhance operati...

Philadelphia, PARemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive collaboration with sales teams to identify prospects and deliver tailored security solutions, addressing technical challenges and enhancing customer engagement through education and presentation...

Dover, DERemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$89K - $148K *

Explore your potential as you manage AWS environments, support cloud operations, and enhance developer tools. Collaborate with teams to ensure seamless infrastructure and contribute to mission-critica...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$65K - $123K *

Optimize storage infrastructure by managing DASD and tape systems, ensuring efficient backups, migrations, and disaster recovery. Collaborate with clients and vendors while mentoring team members to e...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $170K *

Unlock your potential as a Senior DevOps Engineer, driving architectural excellence and automation across agile teams. Collaborate with cross-functional partners to enhance delivery platforms, ensurin...

Pennsylvania, USRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $170K *

Join us to shape the future of DevOps by providing technical leadership and architectural direction across agile teams. Drive automation, enhance developer experience, and champion a culture of contin...

Massachusetts, USRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $200K *

Champion the evolution of DevOps practices by providing technical leadership and architectural direction across agile teams, enhancing software delivery speed and reliability while fostering a culture...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$106K - $190K *

Join a dynamic Threat Intelligence team to drive vulnerability detection and response, enhancing security measures and protecting policyholders through innovative solutions and collaboration across mu...

CanadaRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.