Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
Quality Engineer (U.S. Army Program Office)
$82K - $172K *
Lead the charge in ensuring product quality for critical defense programs, overseeing quality management throughout the lifecycle, collaborating with stakeholders, and driving compliance with industry...
Reposted 1 week ago
IT Service Management Specialist
$80K - $95K *
Drive IT Service Management excellence by overseeing ServiceNow integration and support for critical U.S. Government missions. Collaborate with stakeholders to enhance ITSM processes and ensure effect...
2 days ago
HRIS/PAYROLL SALES EXECUTIVE (REMOTE)
$80K - $95K *
Drive new business growth by managing the full sales cycle for a cloud HCM suite. Engage with small to mid-sized businesses, delivering tailored solutions and building strong referral networks to exce...
2 weeks ago
Commissioning Technician/Specialist
$80K - $95K *
Unlock potential by providing technical support throughout the commissioning lifecycle of mission-critical facilities. Collaborate with engineers and stakeholders to ensure successful execution of com...
Yesterday
$88K - $105K *
Champion the successful delivery of complex projects, guiding financial institutions in adopting innovative loan origination software. Manage timelines, risks, and stakeholder expectations to ensure p...
1 week ago
Sr. Manager, Customer Success - Healthcare Cybersecurity ( Armis/ Veza)
$158K - $208K *
Champion customer success in healthcare cybersecurity by bridging technical teams and stakeholders. Lead portfolio performance, mentor teams, and drive adoption of security strategies across clinical...
2 weeks ago
$94K - $157K *
Lead the charge in transforming data operations by executing complex ETL processes, ensuring data integrity, and facilitating seamless integrations within SAP environments to support enterprise-wide i...
4 weeks ago
Junior Systems Engineer (W/ 1 day telework)
$119K - $161K *
Join a team that's dedicated to delivering high-quality software solutions. Collaborate with stakeholders to gather requirements, support developers, and ensure successful Agile delivery throughout th...
3 weeks ago
$130K - $135K *
Join a team that's dedicated to enhancing federal cybersecurity compliance through advanced risk management and governance. Leverage your expertise to conduct assessments, manage authorizations, and e...
1 week ago
Subject Matter Expert (SME) Cybersecurity Architect
$190K - $265K *
Transform cybersecurity architecture for a large federal program. Lead the integration of security controls across various platforms and systems, ensuring compliance with federal standards while drivi...
3 weeks ago
Lead Consultant - Network Security
$98K - $167K *
Innovate within our network security team by leading the engineering and automation of enterprise security platforms. Drive technical excellence and enhance infrastructure management through modern pr...
1 week ago
Mainframe Systems Programmer - Network
$65K - $126K *
Join a team that's dedicated to optimizing mainframe network systems. Leverage your expertise in planning, installing, and maintaining software while ensuring system performance and reliability. Colla...
2 weeks ago
Cyber Security - Manager (Engineering)
$120K - $145K *
Join a team that's dedicated to protecting digital assets by designing and implementing innovative cybersecurity solutions. Collaborate with leadership and mentor peers while navigating a dynamic envi...
Reposted 4 weeks ago
ServiceNow System Administrator
$87K - $135K *
Lead a dedicated team managing the ITSM platform, overseeing user access, catalog maintenance, and performance monitoring to enhance IT service delivery for a federal agency. This role drives operatio...
3 weeks ago
Agentic Workforce Adoption Manager
$80K - $100K *
Help us drive the adoption of AI solutions, transforming customer workflows and enhancing business outcomes. Collaborate with teams to ensure seamless integration and maximize value delivery for our c...
3 weeks ago
Service Delivery Manager - Infrastructure Operations, Workload Automation & Incident Response?
$110K - $130K *
Drive operational excellence by leading infrastructure and workload automation services. Oversee incident response and service delivery, ensuring high performance and reliability across diverse techno...
2 days ago
Senior Project Manager - 100% Remote
$110K - $130K *
Transform complex enterprise technology programs by leading cloud, data, and analytics initiatives. Collaborate with cross-functional teams to deliver best-in-class project outcomes using Agile method...
3 weeks ago
Senior Public Sector Compliance Manager
$110K - $130K *
Champion compliance by developing and managing FedRAMP standards and processes. Ensure our cloud services remain secure and meet federal requirements through effective oversight and strategic initiati...
3 weeks ago
$130K - $140K *
Shape the future of security by leading efforts to protect and modernize a federal platform. Balance legacy system maintenance with the development of a secure cloud-based solution, ensuring complianc...
1 week ago
Global Security Solutions Lead
$150K - $180K *
Take ownership of the Microsoft Security Solutions area, driving strategy and sales execution. Lead cross-functional teams to optimize performance, align priorities, and translate market opportunities...
1 week ago
Systems Engineering Specialist (Active Directory/Azure AD/Identity)
$120K - $145K *
Lead the design and implementation of Active Directory and Azure AD solutions, ensuring seamless integration and security across platforms. Collaborate with a dedicated team to enhance identity manage...
Reposted 2 weeks ago
Configuration Management Specialist
$95K - $115K *
Shape the future of configuration management by overseeing hardware inventory, documentation, and product releases. Collaborate with teams to implement effective change management processes throughout...
Today
$144K - $170K *
Transform critical business applications by developing robust software solutions. Collaborate with clients and government leads to gather requirements, ensuring high-quality delivery in a dynamic, Agi...
2 weeks ago
$119K - $175K *
Drive complex security initiatives, mentor engineers, and lead investigations into high-impact incidents, focusing on AI/LLM security posture and compliance across multiple domains...
2 weeks ago
$67K - $108K *
Drive outside plant project support by managing materials, tracking inventory, and ensuring accuracy in reporting. Collaborate with teams to enhance processes and support construction efforts while ma...
3 days ago
What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.