Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

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$82K - $172K *

Lead the charge in ensuring product quality for critical defense programs, overseeing quality management throughout the lifecycle, collaborating with stakeholders, and driving compliance with industry...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $95K *

Drive IT Service Management excellence by overseeing ServiceNow integration and support for critical U.S. Government missions. Collaborate with stakeholders to enhance ITSM processes and ensure effect...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Drive new business growth by managing the full sales cycle for a cloud HCM suite. Engage with small to mid-sized businesses, delivering tailored solutions and building strong referral networks to exce...

Wichita, KSRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Unlock potential by providing technical support throughout the commissioning lifecycle of mission-critical facilities. Collaborate with engineers and stakeholders to ensure successful execution of com...

New Jersey, USRemote

Yesterday

  •   5 - 7 years exp.  •   Staffing

$88K - $105K *

Champion the successful delivery of complex projects, guiding financial institutions in adopting innovative loan origination software. Manage timelines, risks, and stakeholder expectations to ensure p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$158K - $208K *

Champion customer success in healthcare cybersecurity by bridging technical teams and stakeholders. Lead portfolio performance, mentor teams, and drive adoption of security strategies across clinical...

Philadelphia, PARemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$94K - $157K *

Lead the charge in transforming data operations by executing complex ETL processes, ensuring data integrity, and facilitating seamless integrations within SAP environments to support enterprise-wide i...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$119K - $161K *

Join a team that's dedicated to delivering high-quality software solutions. Collaborate with stakeholders to gather requirements, support developers, and ensure successful Agile delivery throughout th...

Annapolis, MDRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $135K *

Join a team that's dedicated to enhancing federal cybersecurity compliance through advanced risk management and governance. Leverage your expertise to conduct assessments, manage authorizations, and e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$190K - $265K *

Transform cybersecurity architecture for a large federal program. Lead the integration of security controls across various platforms and systems, ensuring compliance with federal standards while drivi...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$98K - $167K *

Innovate within our network security team by leading the engineering and automation of enterprise security platforms. Drive technical excellence and enhance infrastructure management through modern pr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$65K - $126K *

Join a team that's dedicated to optimizing mainframe network systems. Leverage your expertise in planning, installing, and maintaining software while ensuring system performance and reliability. Colla...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's dedicated to protecting digital assets by designing and implementing innovative cybersecurity solutions. Collaborate with leadership and mentor peers while navigating a dynamic envi...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$87K - $135K *

Lead a dedicated team managing the ITSM platform, overseeing user access, catalog maintenance, and performance monitoring to enhance IT service delivery for a federal agency. This role drives operatio...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $100K *

Help us drive the adoption of AI solutions, transforming customer workflows and enhancing business outcomes. Collaborate with teams to ensure seamless integration and maximize value delivery for our c...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive operational excellence by leading infrastructure and workload automation services. Oversee incident response and service delivery, ensuring high performance and reliability across diverse techno...

Pennsylvania, USRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Transform complex enterprise technology programs by leading cloud, data, and analytics initiatives. Collaborate with cross-functional teams to deliver best-in-class project outcomes using Agile method...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Champion compliance by developing and managing FedRAMP standards and processes. Ensure our cloud services remain secure and meet federal requirements through effective oversight and strategic initiati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $140K *

Shape the future of security by leading efforts to protect and modernize a federal platform. Balance legacy system maintenance with the development of a secure cloud-based solution, ensuring complianc...

Fairfax, VARemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Take ownership of the Microsoft Security Solutions area, driving strategy and sales execution. Lead cross-functional teams to optimize performance, align priorities, and translate market opportunities...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Lead the design and implementation of Active Directory and Azure AD solutions, ensuring seamless integration and security across platforms. Collaborate with a dedicated team to enhance identity manage...

Chicago, ILRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Shape the future of configuration management by overseeing hardware inventory, documentation, and product releases. Collaborate with teams to implement effective change management processes throughout...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$144K - $170K *

Transform critical business applications by developing robust software solutions. Collaborate with clients and government leads to gather requirements, ensuring high-quality delivery in a dynamic, Agi...

Springfield, VARemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$119K - $175K *

Drive complex security initiatives, mentor engineers, and lead investigations into high-impact incidents, focusing on AI/LLM security posture and compliance across multiple domains...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$67K - $108K *

Drive outside plant project support by managing materials, tracking inventory, and ensuring accuracy in reporting. Collaborate with teams to enhance processes and support construction efforts while ma...

Madison, WIRemote

3 days ago

  •   Less than 5 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.