Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

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1
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$100K - $135K *

Drive change management initiatives to enhance IT service processes and user adoption. Collaborate with multidisciplinary teams to deliver effective training, communications, and assessments, ensuring...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Accelerate progress at the forefront of cybersecurity by leveraging your SOC expertise to triage alerts, analyze threats, and implement effective response actions, ensuring robust protection for clien...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Transform intelligence analysis by leveraging your expertise and analytical skills. Collaborate with a dynamic team to support critical missions, utilizing advanced technology and methodologies to dri...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Transportation

$88K - $154K *

Elevate your career by installing and programming advanced electronic security systems. Collaborate with a dynamic team to ensure the integrity of communication and power systems while adhering to ind...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $240K *

Shape the future of enterprise security by leading vulnerability management initiatives. Drive strategy, execution, and collaboration across teams to enhance risk reduction and improve security outcom...

Charlotte, NCRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a dynamic team as a SOC Engineer, where you'll onboard customers into managed security services, configure Microsoft security tools, and ensure reliable telemetry across diverse environments, all...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's at the forefront of cybersecurity, leading a high-performing group of threat analysts in a dynamic, hands-on role. Oversee daily operations, enhance incident response, and drive str...

Overland Park, KSRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$89K - $144K *

Transform user experiences by providing advanced desktop support across multiple locations. Ensure efficient operation of devices and applications, troubleshoot issues, and collaborate with IT teams t...

Rockville, MDRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$131K - $243K *

Join a team that's reshaping operations by supporting the Hyperion system and Oracle Planning tool conversion. Play a crucial role in data integration and foster cross-functional collaboration to meet...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $125K *

Drive new business in healthcare technology by engaging with hospitals and ambulatory organizations. Leverage AI-enabled solutions and clinical documentation services to meet client needs and achieve...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Help us advance Geospatial AI by developing cloud-native services and backend systems. Collaborate with top engineers and data scientists to create innovative solutions that transform vast data into a...

Redmond, WARemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Shape the future of Geospatial AI by developing cloud-native services and backend systems. Collaborate with top engineers and data scientists to deliver innovative solutions that transform vast data i...

Springfield, VARemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock your potential as a Software/ML Engineer, collaborating on cutting-edge Geospatial AI projects. Contribute to cloud-native services and backend systems, driving innovation from concept to deplo...

Reston, VARemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Explore a dynamic role supporting critical ServiceNow implementations, leveraging your expertise in software development and customization to enhance operational efficiency and user experience for a k...

Washington DC, USRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$127K - $172K *

Engage with us to enhance cybersecurity for vital applications. Leverage your Splunk expertise and collaborate with a dynamic team to secure data, assess vulnerabilities, and implement robust security...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$82K - $172K *

Empower acquisition success by supporting contract specialists in reviewing, coordinating, and managing federal acquisition processes, ensuring compliance and efficiency across all stages of contract...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$68K - $143K *

Advance your career by managing complex contracts for Federal Government projects. Utilize your expertise to deliver solutions that meet customer needs while resolving challenges efficiently and colla...

Amarillo, TXRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Drive strategic contract management and proposal development within the Defense and Civil Space Market, leveraging extensive federal contracting expertise to foster relationships and navigate complex...

Virginia, USRemote

4 days ago

  •   11 - 15 years exp.  •   Information Technology

$140K - $180K *

Engage with key stakeholders to manage contracts and proposals, leveraging extensive federal contracting expertise to drive strategic outcomes in the Defense and Civil Space Market while fostering col...

Virginia, USRemote

2 days ago

  •   11 - 15 years exp.  •   Information Technology

$81K - $122K *

Join a team that's redefining HR technology solutions by optimizing and supporting complex systems. Collaborate with stakeholders to translate business needs into effective HRIS solutions, ensuring re...

State College, PARemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$75K - $126K *

Innovate with us to enhance network security platforms, ensuring robust protection and operational efficiency. As a key engineer, you'll tackle complex challenges, automate processes, and collaborate...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$143K - $196K *

Drive compliance and security excellence in FedRAMP programs, collaborating across teams to ensure federal authorization requirements are met. Lead project management efforts, audits, and continuous m...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by supporting Federal contracts in healthcare. Collaborate with a dedicated team to enhance services for American Indians and Alaska Natives, ensuring effective contract management...

South Dakota, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $120K *

Transform cloud security operations by enhancing AWS and Azure environments. Lead initiatives to secure cloud-native capabilities, manage incident responses, and collaborate with engineering teams to...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $100K *

Lead the charge in implementing safety programs to minimize workplace risks and ensure compliance with OSHA standards across multiple facilities. Manage safety assessments, training, and incident inve...

Herndon, VARemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.