Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$110K - $130K *

Shape the future of provider network contracting by leading strategic initiatives, negotiating complex agreements, and collaborating across departments to enhance quality, affordability, and sustainab...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $150K *

Unlock potential by leading complex evaluations in healthcare innovation. Collaborate with a diverse team to enhance Medicare and Medicaid services through rigorous research, technical expertise, and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$73K - $125K *

Transform clinical review processes by conducting thorough prepayment and post-payment assessments of inpatient admissions. Leverage your expertise to ensure compliance, support appeals, and enhance q...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $197K *

Execute comprehensive site monitoring and management to ensure compliance with study protocols, regulations, and sponsor requirements, enhancing project predictability and quality throughout the clini...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$153K - $203K *

Drive global access and pricing strategies for hematology assets, ensuring timely reimbursement and optimal patient access. Collaborate with cross-functional teams to develop evidence-based toolkits a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$172K - $232K *

Lead the GCP Inspection Management team to ensure inspection readiness and compliance. Oversee strategy development, cross-functional collaboration, and risk mitigation for successful regulatory inspe...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in enhancing rehabilitation operations across multiple facilities. Drive clinical excellence, manage staff, and ensure compliance while fostering a supportive environment for both pati...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$127K *

Contribute to transforming virtual primary care by delivering exceptional patient assessments, treatment plans, and ongoing support. Collaborate with healthcare teams while leveraging technology to en...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Grow your career with us as you oversee clinic operations, enhance patient care, and lead a dedicated team. Drive efficiency, manage budgets, and ensure compliance while fostering communication and co...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead a dedicated team in managing operations, ensuring compliance, and enhancing resident services while fostering a culture of safety and quality improvement. Drive financial stability and effective...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $168K *

Lead the charge in delivering exceptional patient care by managing a pharmacy team, promoting best practices, and ensuring compliance with regulations while fostering a culture of excellence and suppo...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$69K - $101K *

Join us to enhance member health outcomes through holistic care management, collaborating with multidisciplinary teams to support individuals with complex needs. Utilize assessments and interventions...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $146K *

Unlock potential by leading payer contract negotiations to enhance relationships, optimize revenue, and ensure compliance with regulations, all while aligning with strategic priorities of the health s...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $130K *

Champion innovative methodologies in medical communications, leading Delphi studies and expert panels. Drive strategic insights and deliver scientifically rigorous findings to support clinical develop...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$129K - $185K *

Innovate global medical strategies for the Companion Animal Pain portfolio, driving growth and customer value through scientific engagement, KOL collaboration, and effective market implementation acro...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Empower patients to achieve optimal physical health by evaluating needs, creating tailored care plans, and delivering effective treatments. Collaborate with a dedicated team to enhance patient outcome...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $125K *

Empower healthcare compliance by enhancing programs, mitigating risks, and driving operational integrity. Collaborate with diverse clients to deliver tailored solutions in a dynamic regulatory landsca...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K - $110K *

Drive impactful medical economics analysis by extracting and synthesizing data to identify trends, enhance financial performance, and support executive decision-making across healthcare operations and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in life sciences strategy execution, driving growth through market engagement and strategic partnerships. Collaborate with cross-functional teams to enhance product relevance and visib...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Optimize patient care by providing clinical support and education for hematology and oncology patients. Collaborate with healthcare teams to ensure effective medication management and serve as a mento...

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$147K - $232K *

Engage with key health-plan relationships to drive revenue retention and growth. Oversee a strategic portfolio, leveraging analytics and executive relationships to enhance member access and operationa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join a pioneering team to build an AI-enabled care delivery platform, bridging clinical expertise and engineering to create safe, effective patient care solutions. Drive innovation from concept to pro...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$118K - $196K *

Lead the charge in developing and executing drug formulary strategies, ensuring compliance with regulations while collaborating with cross-functional teams to enhance pharmacy utilization management a...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.