Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $109,869
$125K - $150K *
Lead the charge in enhancing veterinary care by fostering a collaborative environment, upholding medical standards, and driving clinician engagement while supporting operational initiatives and commun...
2 weeks ago
$110K - $130K *
Drive healthcare transformation by leading advanced consulting initiatives, enhancing delivery systems, and improving health outcomes. Collaborate with clients and stakeholders to implement strategic...
2 weeks ago
Healthcare Services Pharmacist
$100K - $120K *
Drive patient care by providing clinical services and enhancing patient experiences while ensuring compliance with all regulatory guidelines and company policies. Facilitate effective communication to...
Reposted 2 weeks ago
Healthcare Services Pharmacist
$100K - $120K *
Lead the charge in providing essential clinical services, enhancing patient care through immunizations and medication management while ensuring compliance with regulatory guidelines and fostering a po...
Reposted 2 weeks ago
Healthcare Services Pharmacist
$100K - $120K *
Champion patient care by delivering clinical services, ensuring compliance, and enhancing experiences through effective communication and healthcare offerings, while fostering a positive, supportive e...
Reposted 2 weeks ago
$105K - $115K *
Optimize medical device utilization in health systems by leveraging expertise in cardiovascular, interventional radiology, and general surgery. Collaborate with stakeholders to drive cost reduction an...
2 weeks ago
$73K - $100K *
Transform patient care by evaluating and treating diverse conditions in an outpatient setting. Collaborate with a dedicated team to enhance recovery and improve quality of life while enjoying a suppor...
2 weeks ago
Advanced Practice Provider (FT) |Urgent Care | Ames | PR2026-018
$90K - $110K *
Empower patient care by providing comprehensive services to individuals of all ages. Collaborate with a dedicated team while working independently to enhance community health and well-being in a suppo...
2 weeks ago
Senior Safety Physician - CNS (remote)
$222K - $356K *
Unlock your potential as a Senior Safety Physician, leading safety oversight for late-stage CNS clinical development. Collaborate with cross-functional teams to drive risk management and regulatory su...
Reposted 2 weeks ago
Senior Director, Global Medical Affairs
$177K - $338K *
Innovate the global medical strategy for a leading drug program. Drive launch readiness, evidence generation, and cross-functional partnerships while serving as the primary medical voice in product li...
Reposted 2 weeks ago
Physical Therapist - Long Term Care - Home care - Full Time
$78K - $128K *
Optimize patient recovery through tailored physical therapy programs, collaborating with interdisciplinary teams to enhance mobility, relieve pain, and improve overall health outcomes for diverse popu...
2 weeks ago
Associate Director, Study Start-Up
$110K - $130K *
Lead the charge in clinical study start-up operations, driving team development and ensuring timely site activation. Collaborate cross-functionally to enhance processes, meet regulatory standards, and...
2 weeks ago
$100K - $120K *
Join a collaborative team providing advanced emergency care for pets. Play a key role in delivering exceptional veterinary services, ensuring the best outcomes through integrated specialist support an...
2 weeks ago
$100K - $120K *
Join a collaborative team to provide advanced emergency care for pets, ensuring optimal outcomes through integrated specialist support and ongoing professional development opportunities...
2 weeks ago
Bilingual (Spanish/English) Transitions of Care Advanced Practice Provider (NP or PA)
$120K - $150K *
Join a team that's dedicated to enhancing patient care through comprehensive post-discharge support. Leverage your expertise in managing complex chronic conditions while collaborating with an interdis...
2 weeks ago
Senior Advisor, Clinical Science (remote)
$168K - $283K *
Lead the charge in advancing early-stage clinical trials for innovative Orexin-targeted therapies. Collaborate cross-functionally to shape scientific strategy, drive execution, and ensure high-quality...
2 weeks ago
Senior Advisor, Clinical Science (remote)
$153K - $268K *
Transform clinical science in late-stage trials for innovative sleep/wake therapies. Collaborate cross-functionally to ensure compliance, drive recruitment, and deliver high-quality results while shap...
2 weeks ago
EmERge Emergency Veterinarian Training Program
$120K *
Reimagine your veterinary career with our immersive EmERge Program, designed to equip you with essential skills and hands-on experience in emergency medicine. Join a collaborative team and transform y...
2 weeks ago
EmERge Emergency Veterinarian Training Program
$120K *
Accelerate your career in emergency veterinary medicine through a comprehensive one-year training program, combining hands-on experience, mentorship, and immersive learning to prepare you for life-sav...
2 weeks ago
Assistant Nurse Manager - OR Eye Team
$80K - $95K *
Lead the charge in optimizing clinical operations for the Ophthalmic Surgical Patient, ensuring efficient patient flow and collaboration among nursing and support staff while championing process impro...
2 weeks ago
$128K - $176K *
Transform complex clinical and regulatory documents into clear, compliant submissions. Collaborate with teams to ensure accuracy and adherence to standards while managing multiple projects in a fast-p...
2 weeks ago
Medical Science Liaison, Southeast (Multiple Territories)
$155K - $175K *
Develop trusted relationships with key stakeholders, delivering scientific insights and supporting prelaunch activities. Operate independently in a dynamic environment, influencing adoption through cr...
2 weeks ago
$100K - $120K *
Join a team that's dedicated to delivering exceptional patient care while supervising pharmacy staff and championing operational excellence in a compliant environment. Contribute to cultural initiativ...
2 weeks ago
Senior Director, Head of Analytical Development
$250K - $275K *
Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...
3 weeks ago
Medical Science Liaison, Northeast (Multiple Territories)
$155K - $175K *
Serve as a key scientific partner in the field, driving prelaunch and launch strategies through trusted relationships, high-quality exchanges, and actionable insights to enhance product adoption and c...
3 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.