Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$95K - $115K *

Transform patient care by providing expert medical management in a dynamic inpatient setting. Collaborate with multidisciplinary teams to deliver comprehensive stroke care, ensuring optimal outcomes t...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Drive exceptional care in the NICU as a Nurse Practitioner, providing comprehensive medical management and collaborating with an interdisciplinary team to enhance patient outcomes and optimize resourc...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Elevate animal care by providing clinical veterinary services for research animals, ensuring compliance and advancing husbandry programs. Collaborate with a dedicated team to support innovative biomed...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Transform patient care by assisting Gastroenterology faculty in delivering comprehensive diagnostic and therapeutic services, ensuring optimal outcomes for adult patients in outpatient and infusion se...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $172K *

Lead pharmacovigilance operations and safety science initiatives, ensuring compliance and quality in drug safety reporting. Oversee vendor performance, manage safety data, and contribute to regulatory...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$246K - $332K *

Drive pediatric development strategy by integrating clinical insights and regulatory commitments across multiple therapeutic areas, ensuring effective execution from candidate transition to post-marke...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$185K - $315K *

Elevate your career by providing essential medical expertise in dermatology, fostering relationships with healthcare professionals, and leading scientific dialogue to drive innovative solutions in a f...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by providing in-home occupational therapy services, evaluating safety, assessing functional needs, and implementing personalized treatment plans to enhance patient independence and qu...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's redefining inpatient coding operations, ensuring quality and compliance while optimizing workflows. Lead a dedicated team to enhance documentation practices and support financial he...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate patient care by developing tailored rehabilitation plans, performing evaluations, and delivering effective treatments. Collaborate with a dedicated team to enhance patient outcomes and ensure...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$78K - $106K *

Transform client payment policies by ensuring accuracy and compliance. Engage with internal and external teams to manage medical policy updates, conduct analyses, and enhance client relationships whil...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$96K - $108K *

Transform patient care by joining our dynamic hospice team as a Travel RN. Provide compassionate support across multiple locations, ensuring quality and continuity of care while collaborating with loc...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's dedicated to enhancing healthcare quality through thorough medical claims audits. Leverage your nursing expertise in a dynamic remote environment, collaborating with experienced aud...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$65K - $115K *

Transform patient care by leading clinical teams, developing treatment plans, and ensuring quality supervision to enhance skills and behaviors for individuals with autism in diverse settings. Empower...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$145K - $195K *

Engage with patients and healthcare providers to streamline access to therapy. Collaborate with internal teams and specialty pharmacies to resolve reimbursement issues and enhance patient support. Dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $120K *

Support a national patient community by providing critical therapy coverage across multiple states, ensuring continuity of care during clinician absences. Collaborate with multidisciplinary teams to d...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$55K - $109K *

Engage in leading the dental Provider Relations team, enhancing provider relationships and operational effectiveness. Drive network management activities to ensure member access to care and improve pr...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $240K *

Lead strategic relationships with influential optometrists and ophthalmologists, shaping the Presbyopia ecosystem through education and engagement. Drive insights and collaboration across medical, mar...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Contribute to the design and execution of clinical studies, ensuring data integrity and quality. Collaborate cross-functionally to drive study activities and support regulatory efforts, while enhancin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Partner with us to enhance clinical IT solutions as an Epic Analyst II, providing critical support, training, and implementation for Epic EHR systems. Collaborate with teams to optimize workflows and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in analytical development, overseeing drug substance and product strategies. Collaborate across teams to ensure compliance and performance, while mentoring a high-performing analytical...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead the technical direction for inhaled dry powder products, ensuring product performance and manufacturability while collaborating with cross-functional teams to navigate development and regulatory...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to enhancing healthcare reporting through Epic tools. Collaborate with stakeholders to gather requirements, design reports, and provide support, ensuring successful projec...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Support our healthcare team by providing critical care and managing patient admissions. Collaborate with diverse medical staff while working autonomously in a dynamic environment. Enjoy a flexible sch...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $173K *

Champion a transformative clinical team, leading 60-70 RNs in delivering exceptional post-discharge care. Drive innovative strategies to enhance patient outcomes and foster a culture of collaboration...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.