Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$210K - $250K *

Shape the future of rural healthcare by delivering comprehensive emergency care in a collaborative environment. Join a dedicated team at a critical access hospital, enhancing community health while en...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $125K *

Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Engage with a collaborative team to provide comprehensive outpatient psychiatric care, balancing productivity and patient well-being while fostering strong interdisciplinary relationships in a mission...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Elevate patient care by delivering virtual health services, ensuring compliance with regulations, and fostering teamwork in a dynamic environment. Utilize your expertise to provide accurate diagnoses...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$205K - $228K *

Champion patient-focused initiatives by leading strategy and execution of ambassador programs. Build relationships with patients and advocacy groups to enhance engagement and ensure their voices shape...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Elevate healthcare marketing by transforming complex science into impactful strategies. Lead multidisciplinary teams to inspire creativity, drive behavior change, and build trusted client relationship...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$185K - $230K *

Shape the future of patient access by leading reimbursement strategies and support for rare disease therapies. Collaborate cross-functionally to enhance provider education and patient understanding, e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Advance the future of pediatric health by leading medical strategy, safety, and clinical communications. Collaborate with healthcare providers and internal teams to enhance product development and ens...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$130K - $150K *

Drive impactful solutions as a Healthcare Technology Manager, optimizing Epic Patient Access systems. Collaborate with clients and teams to enhance workflows and deliver sustainable results in a suppo...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$250K - $300K *

Deliver exceptional emergency care by diagnosing and treating patients, collaborating with a multidisciplinary team, and ensuring holistic support for families in a dynamic healthcare environment...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Drive impactful clinical consulting by bridging expertise in real-world data with strategic insights. Collaborate across teams to enhance health outcomes research and contribute to thought leadership...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Join a team that's passionate about transforming complex scientific data into engaging communications. Collaborate with cross-functional experts to deliver high-quality medical content and strategies...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $145K *

Elevate community operations by leading a dedicated team to ensure exceptional resident experiences, financial performance, and strategic growth in a collaborative environment focused on compassion an...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive network expansion by engaging providers and negotiating contracts to enhance Medicare services. Collaborate with a remote team to ensure network adequacy and build strong relationships with heal...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $225K *

Drive scientific engagement as a Senior Medical Science Liaison, fostering relationships with Key Opinion Leaders and healthcare professionals. Leverage your expertise in cardiovascular disease to sup...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion the advancement of nursing practice by leading evidence-based initiatives, collaborating with multidisciplinary teams, and enhancing patient outcomes through education and mentorship in acute...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Elevate your career by providing comprehensive outpatient care in a collaborative environment. Join a dedicated team focused on quality, patient-centered services while building lasting relationships...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's dedicated to enhancing customer education and satisfaction through expert training on ultrasound products. This hybrid role involves travel and collaboration with healthcare profess...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$90K - $105K *

Lead clinical excellence by overseeing nursing operations, ensuring quality patient care, compliance, and staff development in a dynamic home health environment. Drive improvements and foster a cultur...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $225K *

Elevate your career by engaging with key opinion leaders and healthcare professionals. This role focuses on scientific collaboration and strategic partnerships, driving impactful medical insights with...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $116K *

Engage with customers to implement and optimize downstream processing technologies, providing technical expertise and support. Collaborate with stakeholders to enhance workflows and ensure successful...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$192K - $252K *

Champion digital transformation by optimizing medical technology solutions and enhancing HCP engagement strategies. Drive adoption and value realization of innovative tools across Field Medical teams...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Join a team that's dedicated to providing exceptional patient care through efficient admissions processes. As an Admissions Registered Nurse, you'll facilitate patient intake, collaborate with medical...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $120K *

Optimize operational excellence in healthcare IT by managing production support, driving issue resolution, and ensuring timely reporting for customer-facing technology delivery...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.