Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$185K - $230K *

Elevate community access to innovative therapies by developing strategic reimbursement solutions, collaborating with stakeholders, and ensuring compliance with healthcare regulations while managing co...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$205K - $240K *

Shape the future of oncology as a Senior Medical Science Liaison, creating impactful scientific engagement within hematology and oncology that enhances patient care. Collaborate with KOLs and cross-fu...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive managed care contracting activities, supporting payer negotiations and relationships. Collaborate with leadership to execute center-level priorities and enhance client satisfaction through effec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Drive provider network excellence by managing data integrity, overseeing contract configurations, and leading cross-functional teams to enhance operational efficiency and compliance in a dynamic TPA e...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in optimizing drug library implementations for smart infusion pumps, collaborating with healthcare teams to enhance medication safety and workflow efficiency across mid- to large-sized...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$185K - $230K *

Unlock potential by leading reimbursement strategies for rare disease therapies, integrating provider education with patient support. Collaborate cross-functionally to enhance access and navigate comp...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $110K *

Shape the future of healthcare payment integrity by developing and enhancing clinical and coding solutions. Collaborate with cross-functional teams to ensure compliance with coding standards and optim...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $190K *

Drive operational excellence in Medical Affairs by managing processes, timelines, and cross-functional coordination to ensure timely execution of strategic initiatives while maintaining compliance and...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$54K - $159K *

Shape the future of healthcare by leading enterprise EHR policy development and workflow standardization. Collaborate across teams to enhance patient safety and operational efficiency while assessing...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$185K - $230K *

Elevate patient access by managing reimbursement strategies for rare diseases. Collaborate with healthcare providers and internal teams to ensure compliance and support patient journeys through comple...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Inspire data-driven decision-making as you lead analytics and predictive modeling efforts. Collaborate across teams to enhance patient engagement, forecast demand, and measure impact, driving strategi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate women's health by delivering comprehensive care in a collaborative, outpatient setting. Build lasting patient relationships while managing diverse gynecologic conditions and enhancing communit...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$175K - $230K *

Empower healthcare innovation by leading a team of Field Clinical Specialists. Drive the successful launch of the Globe Pulsed Field System through training, support, and relationship-building with he...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Empower patients by delivering personalized mental health care in a collaborative environment. Engage in both inpatient and outpatient settings, ensuring high-quality treatment while enjoying a flexib...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in managing daily operations and enhancing patient care quality while supervising staff and fostering a collaborative environment for optimal outcomes in a diverse healthcare setting...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$500K+*

Unlock your potential in a fully remote role focusing on body and general radiology. Join a dynamic team, enjoy competitive compensation, and benefit from advanced technology in a supportive environme...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$272K - $340K *

Join a team that's driving CMC strategy and execution for innovative therapies. Lead cross-functional efforts in drug and device development, ensuring compliance and operational excellence from clinic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Help us shape the future of pulmonary care by leveraging your clinical expertise to drive product development, enhance workflows, and ensure effective solutions for COPD, asthma, and other pulmonary c...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $325K *

Unlock the potential of age-friendly health systems by providing strategic clinical leadership and guidance. Collaborate with health systems to implement the 4Ms framework, driving improvements in car...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Lead the charge in providing remote clinical oversight for Dermatology PAs, ensuring high-quality patient care and compliance with regulations. Collaborate with a dedicated team to foster clinical exc...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Transform billing operations by leading a team to optimize healthcare revenue cycle processes, ensuring timely and accurate claims submission while driving performance improvements and fostering stron...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Join a team that's dedicated to providing exceptional women's health care. As an OB/GYN, you'll deliver comprehensive obstetric and gynecologic services, collaborate with specialists, and contribute t...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.