Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$153K - $268K *

Join our team to provide expert clinical pharmacology insights, driving dose selection and study design for innovative therapies. Collaborate with cross-functional teams to translate complex data into...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$274K - $371K *

Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $86K *

Develop and implement clinical services for students and families, collaborating with school staff to enhance mental health support and ensure effective treatment planning and crisis intervention in a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$236K *

Join a dedicated team providing comprehensive pediatric care in a vibrant community health center. Enjoy flexible scheduling, a supportive environment, and the opportunity to make a meaningful impact...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$122K *

Champion comprehensive pediatric care by delivering primary services in a community health center. Collaborate with a dedicated team to manage acute and chronic conditions, ensuring quality health out...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$81K *

Inspire excellence in nursing care by delivering compassionate, quality support to residents. Collaborate with a dedicated team to enhance the well-being of individuals in a nurturing environment, ens...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$71K - $97K *

Join a dedicated team as you support members in care coordination, focusing on health needs, education, and lifestyle modifications while managing records and completing assessments remotely. Enjoy a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $107K *

Join a team that's transforming healthcare through data-driven insights. As a Senior Medical Economics Analyst, you'll lead analytics initiatives, mentor a team, and collaborate with leaders to enhanc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$77K - $121K *

Join a team that's redefining coding excellence by leading operational strategies, managing staff performance, and ensuring compliance in inpatient coding processes to enhance efficiency and quality a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Join a dedicated team of pediatric professionals to provide comprehensive care, ensuring patient satisfaction and quality treatment in a supportive environment. Enjoy a balanced work-life schedule wit...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform healthcare outcomes by leveraging clinical expertise to review medical records, ensuring compliance with government standards while fostering collaboration and maintaining confidentiality in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$185K - $230K *

Unlock potential by developing strategic access plans for community healthcare, ensuring streamlined reimbursement processes and compliance while collaborating with stakeholders to enhance patient acc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Empower the clinical support team by coordinating complex cases, mentoring junior counselors, and enhancing protocols. Your expertise will drive effective communication and quality standards in geneti...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Champion patient care by filling prescriptions, counseling customers, and supporting pharmacy operations. Collaborate with healthcare teams to enhance wellness programs and ensure compliance with regu...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $135K *

Join a team that shapes innovative medical strategies, driving excellence in healthcare content. Collaborate with experts, cultivate client relationships, and inspire teams to elevate project outcomes...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$185K - $230K *

Empower patient access by leading reimbursement strategies in rare diseases. Collaborate cross-functionally to navigate complex pathways, educate providers, and support patients, ensuring compliance a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$185K - $230K *

Advance patient access and reimbursement strategies in rare diseases. Collaborate cross-functionally to educate providers and support patients, ensuring compliance and effective navigation of complex...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $150K *

Transform healthcare insights by leading client engagements with real-world data. Drive business development and project delivery while building long-term client relationships in a dynamic, hybrid wor...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$92K - $110K *

Unlock potential by joining our dynamic team as a Nurse Practitioner or Physician Assistant, where you'll provide exceptional occupational medicine care, manage patient health plans, and ensure qualit...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $184K *

Drive operational excellence by leading physician practices in Ohio. Collaborate with clinical and regional teams to enhance performance, accountability, and patient experience while translating data...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $180K *

Champion the use of innovative medical technology by training and supporting clinical staff in the effective application of the Globe PF System, ensuring successful clinical trials and enhancing patie...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance your career as a Telehealth Clinical Supervisor, providing leadership and clinical oversight to therapists delivering IOP-level care. Collaborate with a dedicated team to enhance patient outco...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $100K *

Join a team that's dedicated to providing compassionate pediatric care, managing a diverse patient load while collaborating with healthcare professionals to enhance community health and ensure optimal...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate your career by leading trauma program initiatives in emergency services. Collaborate with multidisciplinary teams to enhance patient care and optimize operational efficiency in a fast-paced en...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate member care by facilitating seamless transitions from hospital to home. Collaborate with healthcare teams to ensure safe discharges, reduce readmissions, and provide comprehensive support thro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.