Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$91K - $112K *

Join a dedicated team delivering top-notch Speech Language Pathology services remotely, enhancing the lives of school-aged children with flexible scheduling and cutting-edge tools. Collaborate with pr...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to delivering exceptional nursing services while overseeing operations and ensuring compliance with regulations. Collaborate with clinical staff to enhance patient care an...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $211K *

Innovate clinical product strategies by analyzing market data and collaborating across departments. Drive product development and regulatory compliance while enhancing clinical initiatives to ensure c...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$68K - $103K *

Shape the future of revenue cycle management by driving process improvements and reducing denials. Collaborate with teams to analyze trends, implement best practices, and enhance client satisfaction t...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$177K - $338K *

Help us advance women's health through innovative clinical trial strategies, where you will conduct, support, and report on global studies for cutting-edge compounds, ensuring adherence to regulatory...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Champion advanced clinical performance in managed care, leading teams to ensure quality, cost-effective member care. Leverage expertise in clinical oversight, policy development, and strategic decisio...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $127K *

Optimize member health outcomes by managing complex care plans, coordinating services, and advocating for quality, cost-effective healthcare. Collaborate with healthcare teams to assess needs and moni...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$228K - $285K *

Shape the future of market access by leading strategic account initiatives, fostering key relationships, and driving collaboration across teams to enhance product access and reimbursement in the oncol...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

Grow your career with a dynamic team providing intensive outpatient therapy for older adults. Collaborate with healthcare professionals to deliver compassionate mental health support, focusing on grou...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $151K *

Champion operational excellence by ensuring radiation safety and EHS compliance across cyclotron manufacturing and PET nuclear pharmacy facilities in the South Central US, while collaborating with cro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $170K *

Transform community health by providing comprehensive primary care services. Engage with diverse patient populations, manage chronic conditions, and collaborate with a dedicated team in a supportive e...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $115K *

Unlock the potential of clinical documentation integrity by driving ICD-10-CM coding accuracy and enhancing provider education. Collaborate with cross-functional teams to support risk adjustment initi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Transform patient care by filling prescriptions, counseling patients, and supporting pharmacy operations. Collaborate with healthcare teams to enhance community wellness and drive growth through innov...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$246K - $332K *

Shape the future of health economics and outcomes research by leading strategic initiatives across the nephrology portfolio, ensuring high-quality evidence generation and collaboration with cross-func...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$122K *

Champion clinical excellence by leading large teams, ensuring strategic alignment, and driving patient recruitment while mitigating risks in clinical operations for successful study execution...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Empower a high-performing management team by setting strategic vision and operational direction to achieve clinical excellence and financial growth while ensuring compliance and fostering strong partn...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate global post-market surveillance by leading a team focused on safety, compliance, and performance of medical devices. Drive field actions, analyze data, and collaborate cross-functionally to en...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$64K - $96K *

Engage in comprehensive risk adjustment audits and compliance reviews, ensuring accurate data submission to CMS. Collaborate with coding teams and management to uphold regulatory standards and improve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $115K *

Empower your career by joining a dynamic team focused on healthcare compliance auditing. Utilize your analytical skills to drive impactful audits and contribute to client deliverables while receiving...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Engage with clinical and operational partners to build relationships, identify needs, and facilitate technology solutions. This role ensures effective communication and collaboration across teams to e...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$60K - $129K *

Partner with us to enhance health outcomes through a comprehensive, collaborative case management approach, engaging with clients and healthcare providers to optimize care plans and ensure quality ser...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$133K - $191K *

Transform revenue cycle operations by leading strategic initiatives, optimizing performance, and fostering collaboration across business units to enhance service delivery and achieve organizational go...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $165K *

Join a dynamic team as a Managing Consultant, driving innovative solutions in Revenue Integrity. Oversee engagements, enhance client relationships, and lead project teams to optimize financial perform...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$74K - $89K *

Elevate healthcare quality by reviewing medical records, ensuring accurate coding, and maintaining compliance with guidelines. Collaborate with teams to enhance coding practices and uphold high standa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.