Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$90K - $150K *

Unlock member value by managing pharmacy solutions, optimizing contract use, and fostering relationships with healthcare systems to enhance operational efficiency and savings...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $150K *

Join a dynamic team to leverage clinical expertise in healthcare consulting, driving improvements in perinatal care and women's health. Collaborate with leaders to analyze data, share best practices...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $150K *

Lead the charge in optimizing payment integrity programs, ensuring effective execution and performance monitoring. Collaborate across functions to drive improvements in operational efficiency and prov...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$182K - $247K *

Drive innovative clinical operations to enhance member care and outcomes. Collaborate across teams to implement strategies, optimize processes, and scale programs, ensuring seamless coordination and e...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by delivering exceptional patient care and pharmacy services. As a vital healthcare professional, you'll fill prescriptions, counsel patients, and support community wellness initiativ...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Transform patient care as a Floating Registered Pharmacist, delivering exceptional service across multiple locations. Collaborate with teams, counsel patients, and ensure compliance while thriving in...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Unlock potential by delivering exceptional patient care as a Registered Pharmacist. You'll fill prescriptions, counsel patients, and support wellness initiatives, all while collaborating with a dedica...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$61K - $104K *

Engage in impactful public health data analysis, utilizing quantitative skills and epidemiological knowledge to enhance surveillance programs and support critical health initiatives...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$78K - $113K *

Innovate healthcare fraud prevention by leading complex investigations, evaluating medical necessity, and collaborating with regulatory agencies to ensure quality member care and safeguard plan assets...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$78K - $113K *

Unlock potential by leading complex investigations into healthcare fraud, waste, and abuse. Collaborate with regulatory agencies and internal teams to ensure compliance and safeguard member care while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$93K - $134K *

Drive impactful data mining initiatives by analyzing complex claims across Medicare, Medicaid, and Commercial sectors. Leverage your expertise to identify anomalies and enhance recovery opportunities...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Optimize reimbursement strategies and regulatory compliance by leading analysis, developing policies, and mentoring teams. Drive operational excellence and foster relationships with stakeholders to en...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in directing clinical rehabilitation operations across multiple practices, ensuring quality patient care and achieving financial and operational objectives through effective management...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Accelerate progress at the forefront of clinical research by managing site operations, ensuring compliance, and fostering strong relationships throughout study phases. Your expertise will drive site p...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform patient safety operations by leading a dedicated team, ensuring compliance, and enhancing pharmacovigilance processes. Collaborate cross-functionally to deliver high-quality safety services...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$92K - $153K *

Join a team that's dedicated to enhancing patient access by managing reimbursement challenges and providing education to healthcare providers. This role requires strong relationship-building skills an...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Lead advanced analytics and statistical modeling to transform complex healthcare data into actionable insights, collaborating with cross-functional teams to solve strategic business challenges and enh...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$73K - $98K *

Join a team that's dedicated to excellence in DRG auditing. Leverage your expertise in MS-DRG and APR-DRG coding to ensure accuracy and compliance while working remotely. Enjoy a collaborative environ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$300K - $350K *

Join a team that's dedicated to providing comprehensive colorectal care. Collaborate with a multispecialty team, support patient access, and enhance program growth in a fully integrated health system...

Today

  •   Less than 5 years exp.  •   Healthcare

$144K - $240K *

Transform healthcare delivery by leading strategic initiatives and optimizing infusion services. Drive client success through expert guidance, operational excellence, and innovative solutions, ensurin...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$92K - $110K *

Transform patient care as a Clinical Practice Leader, driving evidence-based practices and enhancing team collaboration in a dynamic Emergency Medicine environment. Lead initiatives to improve outcome...

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in ensuring food safety through comprehensive audits, collaborating with teams to uphold certification standards, and providing expert recommendations for compliance and improvement in...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$114K - $210K *

Champion the development of regulatory documents for global submissions, managing timelines and cross-functional collaboration to ensure quality and compliance with industry standards while mentoring...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in managing client engagements within healthcare, translating complex data and workflows into actionable solutions. Drive customer success by fostering relationships and guiding client...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion clinical monitoring and site management processes, ensuring compliance with protocols and regulations. Develop strong relationships with investigational sites while conducting thorough assess...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.