Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$90K - $110K *

Elevate senior care by delivering high-quality, relationship-based primary care. Enjoy autonomy and flexibility while collaborating with a dedicated team to improve patient outcomes and enhance the li...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance clinical documentation accuracy by collaborating with healthcare teams to ensure comprehensive patient records, reflecting severity of illness and risk of mortality, while maintaining complian...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate operational excellence by leading claims operations, ensuring compliance and efficiency while driving process improvements and team development. Collaborate across functions to meet client com...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Accelerate progress at the forefront of newborn health by leading strategic initiatives, managing multi-country programs, and driving impactful interventions to reduce neonatal mortality and stillbirt...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $100K *

Help us optimize Epic applications by leading projects, troubleshooting issues, and ensuring seamless integration. Collaborate with teams to enhance workflows and provide expert support, all while mai...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $105K *

Lead the Nursing Department to ensure quality care and compliance, overseeing staff, policies, and performance improvement initiatives while fostering a compassionate environment for Guests...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$190K - $300K *

Build strategic relationships with scientific leaders to drive innovation in Pulmonary Hypertension. Engage in scientific exchange, support research initiatives, and enhance understanding of therapeut...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K *

Champion quality care by leading facility operations, ensuring compliance with regulations, and fostering a positive environment for staff and residents. Drive strategic initiatives and maintain high...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$115K - $120K *

Join a team that's dedicated to delivering remote mental health care, supporting clients through marital and family challenges. Utilize your expertise to foster therapeutic relationships and guide mea...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Drive impactful data analysis and risk management for global clinical trials, interpreting complex data to identify trends and risks. Lead cross-functional teams in enhancing study quality and patient...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Innovate post-acute payment integrity by developing and optimizing audit concepts for DME, home health, and infusion therapy claims. Collaborate cross-functionally to ensure compliance and enhance ope...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $100K *

Lead the nursing program in a long-term care facility, ensuring high standards of resident care and compliance with regulations. Oversee operations, staff management, and clinical program development...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$127K - $157K *

Join a team that's redefining healthcare quality by owning HEDIS performance measures. You'll design and implement impactful programs, collaborate across teams, and drive improvements to enhance patie...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $172K *

Elevate veterinary care by interpreting digital cytology and hematology cases. Collaborate with veterinarians, ensure quality control, and contribute to outreach efforts while maintaining high standar...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Champion scientific exchange and clinical research in Cardiovascular & Metabolism. Engage with medical leaders, enhance understanding of research goals, and gather insights to drive strategic initiati...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion quality control excellence by leading teams in Chemistry, Virology, and Immunochemistry. Ensure compliance with regulatory standards while driving process improvements and supporting cross-fu...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$208K - $220K *

Drive enterprise leadership in clinical quality and regulatory readiness, ensuring consistent standards and governance across regions. Collaborate with stakeholders to translate quality insights into...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $120K *

Manage on-site and in-house service for complex medical equipment, troubleshooting electronic and mechanical issues while ensuring high customer satisfaction and minimizing downtime. Collaborate with...

1 week ago

  •   5 - 7 years exp.  •   Staffing

$76K - $148K *

Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$79K - $96K *

Unlock potential by delivering compassionate nursing care, ensuring quality and adherence to individual care plans while collaborating with a dedicated clinical team in a supportive environment...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Lead a dedicated team in the Emergency Department and ICU, driving clinical excellence and patient safety. Collaborate with physicians and staff to enhance care quality and outcomes, making a signific...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Transform healthcare auditing by conducting thorough medical claims reviews. Collaborate with a dynamic team to ensure compliance and improve processes while working remotely in a fast-paced environme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $150K *

Join a team that's dedicated to enhancing healthcare revenue cycles by conducting assessments, managing operations, and building client relationships. Leverage your expertise to drive improvements and...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$227K - $385K *

Elevate member care by overseeing utilization management and evaluating treatment appropriateness. Collaborate with multidisciplinary teams, ensuring compliance with clinical standards and regulations...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.