Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$160K - $200K *

Shape the future of healthcare by leading operational excellence and strategic growth at a premier orthopedic specialty hospital. Drive performance, enhance patient experience, and foster collaboratio...

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$79K - $99K *

Unlock potential by delivering exceptional patient care as a Physical Therapist in diverse settings. Collaborate with a dedicated team to assess, treat, and develop innovative programs that enhance pa...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $99K *

Collaborate with patients and healthcare teams to assess, treat, and develop innovative therapy programs in a dynamic outpatient and inpatient setting, enhancing patient care and departmental operatio...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $99K *

Grow your career with a dynamic Physical Therapist role in diverse settings, including outpatient clinics and home health. Collaborate with patients and staff to enhance treatment programs and improve...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $99K *

Join a team that's dedicated to enhancing patient care through innovative physical therapy practices in diverse settings, including outpatient clinics and home health, while fostering professional gro...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $258K *

Unlock your potential as a Senior Engagement Manager, leading complex consulting projects for pharmaceutical clients. Drive strategic medical initiatives, foster client relationships, and mentor teams...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$220K - $250K *

Shape the future of neurology by building partnerships with Medical Experts, generating insights, and collaborating across teams to enhance patient care and drive innovation in a dynamic healthcare la...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in labeling and nutrition compliance, overseeing the source-to-label process, ensuring regulatory adherence, and managing cross-functional deliverables to maintain product integrity an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$141K - $204K *

Drive strategic growth for DSD by leveraging data, analytics, and tools to enhance operational performance and achieve expansion goals. Collaborate with leadership to support initiatives that elevate...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $155K *

Empower individuals by providing evidence-based mental health support to patients aged 13+. Collaborate with a dedicated clinical team in a fully remote environment, enhancing patient care and profess...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Unlock your potential by providing specialized pharmaceutical care in diverse clinics. Collaborate with a multidisciplinary team to enhance patient outcomes through medication management, education, a...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$73K - $110K *

Drive coding quality and compliance by analyzing data, supporting audits, and enhancing documentation practices. Collaborate with teams to ensure accurate coding and adherence to regulatory standards...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $97K *

Elevate community health by delivering compassionate nursing care, ensuring adherence to individual care plans, and fostering a supportive environment for residents and team members through establishe...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$153K - $268K *

Join a team that's advancing regulatory strategies for drug substance manufacturing. Lead the charge in selecting and justifying Regulatory Starting Materials, ensuring compliance with global guidelin...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$98K - $132K *

Transform healthcare by leading Risk Adjustment strategies and educational initiatives. Collaborate with teams to enhance coding accuracy and documentation, ensuring compliance and delivering impactfu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Elevate care standards by leading our Clinical Department, inspiring your team, and ensuring residents receive exceptional nursing services through effective management and a positive culture...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$190K - $220K *

Champion impactful scientific engagement by building relationships with key stakeholders, translating clinical data into actionable insights, and driving prelaunch strategies in a dynamic environment...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $159K *

Lead clinical operations in review of medical certifications for leave requests. Build and manage a dedicated team, standardize workflows, and ensure compliance while driving continuous improvements i...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $170K *

Join a team that's dedicated to advancing tuberculosis (TB) prevention and care. As a senior technical advisor, you'll lead innovative strategies, collaborate with global partners, and enhance TB prog...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$59K - $108K *

Elevate patient care by providing comprehensive nursing support across various clinics. Collaborate with multidisciplinary teams to ensure seamless care delivery, while adapting to diverse patient nee...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$59K - $108K *

Join a dynamic team to provide compassionate, patient-centered care across diverse clinic settings. Collaborate with healthcare professionals to enhance patient experiences and streamline care for fam...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$59K - $108K *

Elevate patient care by providing compassionate nursing support across diverse clinics. Collaborate with multidisciplinary teams to ensure seamless care for families, from pediatrics to specialty serv...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$59K - $108K *

Support diverse patient care across multiple specialties, ensuring personalized, compassionate nursing. Collaborate with teams to enhance patient outcomes and streamline care processes in a dynamic cl...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$67K - $98K *

Join our team as a Registered Nurse to provide acute psychiatric care to adults. Utilize your nursing skills in treatment planning and delivery while supervising support staff in a therapeutic inpatie...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $250K *

Unlock potential by leading innovative clinical documentation initiatives that enhance quality, compliance, and revenue cycle outcomes. Collaborate with cross-functional teams to redefine workflows an...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.