Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$80K - $95K *

Lead transformative nursing operations across Iowa, ensuring high standards of care and compliance. Inspire teams to deliver compassionate, person-centered care while driving operational efficiency an...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate nursing operations by leading a compassionate team, ensuring regulatory compliance, and fostering a person-centered care model that enhances resident dignity and independence across Iowa's ski...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Champion a culture of compassionate care as you lead nursing operations across Iowa. Drive excellence in clinical standards, mentor staff, and ensure regulatory compliance while enhancing resident exp...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Shape the future of nursing operations by leading a dedicated team, ensuring compliance, and fostering a compassionate care environment that prioritizes resident dignity and independence while driving...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join our team to lead nursing operations across Iowa, ensuring high clinical standards and regulatory compliance while fostering a compassionate, person-centered care environment for residents and sta...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Drive nursing excellence across Iowa by leading operations, ensuring compliance, and fostering a compassionate care environment. Collaborate with teams to enhance resident experiences and support staf...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Inspire change by leading nursing operations across Iowa, ensuring compliance and high standards of care. Collaborate with teams to enhance resident experiences and drive operational efficiency while...

Ottumwa, IARemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower nursing excellence by leading operations across Iowa, ensuring compliance and high standards. Champion person-centered care while mentoring staff and enhancing team efficiency to positively im...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Optimize customer adoption by leading product training and engagement, ensuring successful go-live and sustained usage. Act as a trusted radiology workflow consultant, driving deep product knowledge a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$72K - $97K *

Join a dynamic team to support global clinical study delivery, ensuring quality and compliance in clinical operations. Collaborate with cross-functional teams to manage study logistics, data tracking...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Optimize clinical support for Heart Alert Service by reviewing ECG episodes, ensuring accurate documentation, and collaborating across functions to enhance patient care and workflow efficiency...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$67K - $199K *

Lead NCQA Health Outcomes and Community-Focused Care Accreditation initiatives, driving quality improvement and compliance across health plans. Collaborate with teams to enhance equitable health outco...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$63K - $114K *

Engage with healthcare providers to enhance performance in HEDIS, STARS, and value-based care. Develop contracts and foster partnerships while leveraging data analytics. Travel within territory requir...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in enhancing rehab services by supervising a multidisciplinary team, ensuring compliance, and driving clinical excellence in a skilled nursing facility setting. Collaborate with manage...

Today

  •   Less than 5 years exp.  •   Healthcare

$87K *

Join a team that's dedicated to enhancing patient independence through effective occupational therapy services, collaborating closely with licensed OTs to implement care plans and support patient prog...

Today

  •   Less than 5 years exp.  •   Staffing

$162K *

Collaborate to assess clients' physical and psychosocial health, diagnose conditions, and implement therapeutic measures. This role requires maintaining licensure and compliance with federal and state...

Today

  •   Less than 5 years exp.  •   Healthcare

$79K - $89K *

Elevate patient care by leveraging advanced technology and personalized plans. Collaborate with a dedicated team to enhance patient experiences while enjoying flexible scheduling and ongoing professio...

Today

  •   Less than 5 years exp.  •   Healthcare

$190K - $252K *

Join a team that's redefining professional coding leadership, overseeing coding operations, quality audits, and education initiatives. Drive strategic objectives that enhance patient care and revenue...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the charge in enhancing rehab services by supervising teams, ensuring compliance, and developing innovative clinical programs to deliver exceptional patient care in a skilled nursing facility set...

Today

  •   Less than 5 years exp.  •   Healthcare

$217K - $294K *

Innovate the U.S. Cardiovascular & Metabolic Medical strategy, leading evidence generation and stakeholder engagement for chronic weight management. Collaborate cross-functionally to ensure launch rea...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $91K *

Contribute to national health data collection efforts by leveraging your nursing expertise and survey research skills. Engage in participant-centered data collection, quality control, and training whi...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Champion the clinician experience by designing and optimizing tools that enhance daily workflows, ensuring seamless integration of clinical data and improving patient care delivery in home settings...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $159K *

Inspire excellence in clinical documentation by leading a team of specialists, ensuring quality assurance, and fostering professional development. Collaborate with stakeholders to enhance operational...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Engage with residents as a trusted Physician, delivering high-quality, person-centered care in skilled nursing facilities. Mentor APPs, improve health outcomes, and enjoy the autonomy of private pract...

Today

  •   Less than 5 years exp.  •   Healthcare

$145K - $165K *

Drive impactful clinical research strategies by collaborating with cross-functional teams, analyzing data, and disseminating findings through publications and presentations. Elevate your career while...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.