Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$85K - $100K *

Join a team that's dedicated to delivering exceptional care in Skilled Nursing. As a key leader, you'll inspire your clinical team, set departmental goals, and ensure residents receive the highest sta...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$199K - $269K *

Shape patient affordability strategies by leading a dynamic team focused on co-pay programs and innovative solutions. Collaborate cross-functionally to enhance operations, optimize performance, and dr...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$191K - $258K *

Shape the future of global safety by leading the development and submission of periodic aggregate safety reports. Drive compliance and collaboration across teams while managing a diverse global team t...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in delivering exceptional nursing care by overseeing operations, guiding clinical practices, and fostering a supportive environment for residents and staff. Utilize your leadership ski...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$207K - $346K *

Lead the charge in evidence-based medical case reviews to ensure high-quality patient care while collaborating with a network of over 500 physician colleagues in a fully remote environment...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Optimize patient access workflows by aligning registration with revenue cycle needs. Collaborate with stakeholders to enhance eligibility processes and improve patient estimates, while mentoring IS st...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $126K *

Lead the charge in enhancing patient care through effective utilization review, ensuring quality and compliance while collaborating with healthcare teams to optimize clinical outcomes and financial pe...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Unlock your potential by joining a thriving multi-specialty clinic, collaborating with a diverse team to deliver quality patient care and utilizing a robust referral network in a collegial, supportive...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Inspire excellence in patient care at a leading multi-specialty clinic, where you'll collaborate with a dynamic team of healthcare professionals to enhance services and drive better outcomes in a supp...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's dedicated to exceptional patient care and outcomes. Work alongside a large, collaborative group of physicians in a supportive environment that prioritizes your growth and offers com...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's redefining internal medicine, collaborating with a skilled group of professionals to deliver high-quality patient care across multiple locations in a supportive, family-friendly atm...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Contribute to a leading multi-specialty clinic by delivering high-quality care as an Internal Medicine Physician. Collaborate with a diverse team to provide excellent patient outcomes in a supportive...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Join a team that's redefining internal medicine with a collaborative, patient-centric approach. Engage with diverse cases, foster professional growth, and enjoy a family-friendly environment in a lead...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Lead the charge in delivering exceptional pharmaceutical care to adult patients in acute settings. Collaborate with interdisciplinary teams to ensure safe medication practices and provide education wh...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive revenue cycle operations by managing processes from entry to adjudication. Lead teams, implement efficiencies, and ensure compliance while optimizing cash collections and performance metrics for...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Empower patient care through expert image interpretation and guidance in diagnostic radiology. Collaborate on quality assurance, oversee technical standards, and educate staff while ensuring optimal p...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$112K - $140K *

Transform product quality management by leading complaint intake, investigation, and resolution processes. Collaborate with cross-functional teams to ensure compliance and enhance patient safety while...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Shape the future of patient care by leading nursing operations across multiple departments, fostering clinical excellence, and enhancing staff development while ensuring quality and safety in a collab...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$76K - $128K *

Empower healthcare professionals and patients by providing expert education on diabetes management. Collaborate with sales teams to enhance territory growth and ensure optimal patient experiences whil...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$123K - $160K *

Champion innovative cancer therapies by leading quality operations for apheresis and treatment centers. Collaborate cross-functionally to ensure compliance and support Kite's rapid expansion in CAR-T...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $188K *

Shape the future of managed care by leading contract negotiations, performance monitoring, and strategic initiatives to optimize reimbursement and enhance payer relationships across healthcare service...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Unlock potential by overseeing clinical trials, ensuring compliance with protocols and regulations. Collaborate with investigators and coordinators to protect participant rights and verify data integr...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $203K *

Transform your career by engaging with key opinion leaders in Urology and Women's Health. Leverage your scientific expertise to drive medical strategies and foster relationships that enhance product u...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $149K *

Transform complex Consumer-Directed Health implementations for major employers. Lead strategy, execution, and client engagement while serving as a subject-matter expert to ensure operational excellenc...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $110K *

Lead the transformation of patient care by enhancing utilization review processes, ensuring quality documentation, and collaborating with healthcare teams to optimize clinical outcomes and financial p...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.