Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$150K - $180K *

Advance global drug safety initiatives by leading pharmacovigilance activities, ensuring compliance with regulations, and collaborating with cross-functional teams to enhance product safety and operat...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$68K - $105K *

Transform your career by configuring and supporting Epic applications. Engage in systems analysis, design, and problem resolution while collaborating with end-users to enhance their experience and str...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Empower patients through innovative telehealth solutions. Join our team of board-certified OB/GYN physicians to deliver high-quality, patient-centered care across Iowa, balancing flexibility with clin...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Engage in a rewarding telehealth role, providing compassionate care across various clinical cases. Enjoy flexible scheduling while delivering high-quality virtual consultations to patients throughout...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $159K *

Empower the Clinical Documentation Integrity team by ensuring staff competency through quality assurance, training, and performance management. Collaborate on action plans and foster associate develop...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$225K - $418K *

Champion advanced analytics to enhance patient outcomes through data-driven insights. Lead a team in analyzing healthcare data, fostering strategic partnerships, and communicating complex findings to...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform patient access by optimizing Epic Cadence workflows. Collaborate with clinical teams to enhance scheduling efficiency and support system improvements, ensuring seamless operations and superi...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to providing exceptional pharmaceutical care in acute settings. As a Clinical Pharmacist, you'll collaborate with healthcare professionals to ensure safe medication practi...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Contribute to patient-centered care by delivering professional medical services, exercising autonomy in decision-making, and collaborating with healthcare teams to ensure optimal patient outcomes and...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$185K - $344K *

Advance enterprise patient intelligence by leading strategy, governance, and analytics. Collaborate across functions to enhance decision-making and drive insights that improve patient outcomes and bus...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Empower healthcare delivery by leveraging health information technology to enhance patient care. Collaborate with health systems and cross-functional teams to align technology with clinical workflows...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Drive health informatics initiatives to enhance care delivery across diverse healthcare systems. Collaborate with stakeholders to align technology solutions with clinical workflows, ensuring complianc...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Transform healthcare delivery by leveraging health information technology to enhance patient care, streamline clinical workflows, and improve operational efficiency across diverse health systems and t...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Transform healthcare delivery by leveraging health information technology to enhance patient care and operational efficiency. Collaborate with health systems and cross-functional teams to align techno...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$82K - $182K *

Analyze healthcare costs and quality outcomes to drive value-based care strategies, collaborating with clinical and financial teams. Lead data-driven insights and financial modeling to enhance operati...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join our team to oversee the comprehensive operations of a PACE program, ensuring effective service delivery, compliance, and financial performance while fostering a culture of innovation and teamwork...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in medication management and patient care as a Clinical Pharmacist. Collaborate with healthcare teams to ensure safe medication practices, oversee pharmacy operations, and educate futu...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$104K *

Unlock your potential as a Physical Therapist, evaluating patients, creating treatment plans, and collaborating with a dedicated team in both Home Health and SNF settings. Enjoy a flexible weekend sch...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$129K - $174K *

Lead a dynamic programming team to enhance data analysis strategies, ensuring high-quality biomedical data presentation while driving efficiency and innovation in a collaborative environment focused o...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$156K - $250K *

Lead the charge in scientific dialogue with key healthcare professionals, providing critical insights and support within your therapeutic area. Utilize your expertise to enhance patient outcomes and f...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Optimize clinical trial operations by leading cross-functional teams, managing vendor relationships, and ensuring compliance with regulatory standards to drive successful study execution and patient e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$129K - $231K *

Elevate nonclinical toxicology operations by managing study execution, ensuring compliance, and fostering collaboration across teams to advance innovative therapies for sleep-wake disorders. Drive acc...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Pioneer healthcare excellence by leading clinical operations and enhancing patient care. Drive financial management, improve service delivery, and foster collaboration among teams to ensure efficient...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $140K *

Champion clinical trial excellence by leading a high-performing CRA team, ensuring compliance with ICH-GCP and local regulations while fostering a positive team culture and optimizing site relationshi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$172K - $233K *

Join a dynamic team as a Senior Medical Science Liaison, driving scientific engagement with healthcare providers to enhance patient outcomes in obesity and related conditions. Collaborate with key opi...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.