Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$175K - $210K *

Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...

RemoteRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $150K *

Join a team that's dedicated to transforming addiction treatment through telehealth. Collaborate with physicians to provide comprehensive care for patients with substance use disorders, ensuring a sup...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $130K *

Elevate patient care by managing clinical support for monitoring systems. Lead diverse teams to enhance customer relationships and ensure effective product utilization post-implementation, driving cli...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Accelerate progress at clinical sites by enhancing patient recruitment strategies and supporting Oncology studies. Collaborate with teams to optimize enrollment processes and ensure effective communic...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $103K *

Champion accurate coding by interpreting diagnoses and resolving claim errors in this remote role. Leverage your expertise to ensure compliance with CPT, ICD-10, and HCPCS standards while collaboratin...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $100K *

Join a high-performing orthopedic team where your expertise enhances patient care. Engage in comprehensive assessments, surgical support, and treatment planning while fostering collaboration for optim...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$235K - $270K *

Unlock your potential as a strategic leader in field medical operations, driving scientific exchange and enhancing patient identification. Collaborate with key opinion leaders while building scalable...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate clinical research by monitoring trials, ensuring compliance with protocols and regulations. Collaborate with investigators to achieve study goals in dermatology and rheumatology, while working...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$60K - $129K *

Transform lives by providing expert case management and crisis intervention for members facing behavioral health challenges. Leverage your clinical skills to develop care plans, coordinate services, a...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K *

Elevate your career by providing clinical support and training for patient monitoring systems. Lead implementation teams, ensure customer satisfaction, and maintain clinical expertise while managing t...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$63K - $98K *

Champion health services coordination for diverse patient populations, ensuring compliance with policies and standards. Conduct assessments, collaborate with interdisciplinary teams, and respond to me...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $140K *

Shape the future of healthcare integration by leading and executing complex HL7 projects. Utilize your expertise in medical informatics and enhancing customer satisfaction while managing dynamic, mult...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the future of patient experience by driving strategic initiatives and operational excellence in a high-volume healthcare contact center. Collaborate with cross-functional teams to enhance service...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Drive clinical operations excellence by managing protocol compliance, delivering budget oversight, and ensuring successful study start-up in alignment with regulatory standards and internal policies w...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive your career with a leadership role focused on Revenue Integrity, overseeing strategic direction, performance metrics, and team development to enhance operational efficiency and client satisfacti...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Take ownership of medication therapy management services, conducting comprehensive reviews and consultations. Collaborate with the MTM product team to ensure accurate data entry and enhance patient ca...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Transform nursing services by overseeing quality care for residents, managing a dedicated team, and ensuring compliance with health standards. Lead with passion and expertise in a supportive environme...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the nursing team in delivering exceptional care to residents while overseeing operations and ensuring quality standards. This role offers mentorship and growth opportunities in a supportive envir...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the charge in delivering exceptional oncology care as a Nurse Manager. Oversee infusion staff, provide direct patient care, and collaborate on healthcare delivery processes while shaping departme...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Transform patient care as a Registered Pharmacist, ensuring accurate prescriptions, providing expert counseling, and driving community wellness initiatives while leading a dedicated pharmacy team...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$200K - $290K *

Contribute to the advancement of cancer therapies by managing analytical development and quality control operations, ensuring compliance with regulatory standards, and collaborating across teams to en...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$185K - $235K *

Optimize family access and reimbursement strategies in a hybrid role, collaborating with healthcare providers and families. Leverage your expertise to navigate complex pathways, ensuring compliance an...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Make your mark at a leading healthcare organization, delivering high-quality, person-centered care in skilled nursing facilities. Collaborate with teams to improve health outcomes while enjoying auton...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $172K *

Transform healthcare delivery by managing CDI operations, liaising with vendors, ensuring quality, and fostering staff development. Join a collaborative team to enhance patient care through innovative...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion the delivery of exceptional nursing services by overseeing operations, managing staff, and ensuring compliance with regulations while fostering a collaborative environment to enhance patient...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.