Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$235K - $310K *

Join a team that empowers translational medicine innovation in early-phase oncology, owning strategies from IND-enabling studies to proof of concept. Drive impactful biomarker integration and clinical...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $175K *

Lead community engagement initiatives to enhance patient advocacy for Becker Muscular Dystrophy. Collaborate with local organizations, educate patients, and build networks to ensure access to quality...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Shape the future of healthcare delivery by leading operations in denials resolution and payment compliance. Drive performance, quality, and financial outcomes while building a high-performing team and...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Join a team that's driving strategic growth and profitability in healthcare solutions. Lead cross-functional initiatives, own P&L, and ensure client success while shaping market strategy and solution...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$225K - $265K *

Shape the future of oncology by leading clinical studies in early-phase development. Collaborate with multidisciplinary teams to drive innovative therapies and ensure high-quality execution of clinica...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $155K *

Empower patient care by joining a dedicated team that provides telephonic support, addresses diverse medical and psychological needs, and enhances patient experiences while ensuring documentation accu...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$69K - $104K *

Unlock your potential by collaborating with leaders to enhance payor performance, streamline revenue cycle operations, and drive innovation in healthcare. Your expertise will ensure impactful engageme...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $231K *

Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...

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Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $322K *

Elevate patient care by providing comprehensive psychiatric services in a dynamic correctional environment. Collaborate with a multidisciplinary team to develop treatment plans and ensure quality ment...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$156K - $212K *

Accelerate progress at the forefront of medical science, engaging with healthcare leaders to enhance patient outcomes through strategic scientific communication and collaboration in rare diseases and...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$211K - $285K *

Lead the charge in late-phase oncology clinical development, collaborating across teams to design and deliver impactful results. Provide expertise in clinical trial science and data analysis, ensuring...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$204K - $276K *

Lead the charge in global observational research, driving clinical operational strategy and execution. Collaborate with cross-functional teams to ensure quality and efficiency in evidence generation t...

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Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$189K - $246K *

Lead clinical pharmacology strategies, integrating PK/PD assessments across development phases. Collaborate with cross-functional teams to guide decision-making and regulatory submissions, ensuring al...

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Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate your career by managing clinical sites and ensuring study quality, patient safety, and regulatory compliance. Collaborate with site teams to support enrollment and deliver impactful clinical r...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$212K - $318K *

Shape the future of patient-centered outcomes in oncology by leading global strategies for clinical assessments and patient experience data, ensuring impactful evidence generation and regulatory succe...

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Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$121K - $182K *

Manage clinical monitoring activities for multiple trials, providing mentorship and oversight to CRAs. Collaborate with teams to ensure compliance and quality, while addressing site-level issues and e...

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Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$71K - $99K *

Join a team that's dedicated to enhancing clinical practices through effective IT solutions. This role involves training, system maintenance, and collaboration with healthcare professionals to optimiz...

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Today

  •   Less than 5 years exp.  •   Healthcare

$108K - $147K *

Lead a dynamic team in enhancing member-centered care through effective utilization management. Drive quality improvement, ensure compliance, and foster strategic partnerships to optimize healthcare d...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$200K *

Bring your expertise to a supportive dental practice focused on patient-centered care. Enjoy flexible scheduling, competitive earnings, and the opportunity to build lasting relationships in a thriving...

Today

  •   Less than 5 years exp.  •   Healthcare

$87K *

Empower your career by providing essential physical therapy services, assisting patients in restoring mobility and achieving their goals while collaborating with a dedicated team in a supportive envir...

Today

  •   Less than 5 years exp.  •   Staffing

$87K *

Take ownership of patient care by delivering effective physical therapy services under supervision. Collaborate with healthcare teams to enhance mobility and function, ensuring compliance with regulat...

Today

  •   Less than 5 years exp.  •   Staffing

$100K - $120K *

Transform the future of food safety and quality assurance by leading compliance programs, enhancing product integrity, and fostering a proactive culture. Collaborate across teams to ensure high standa...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$113K - $155K *

Champion quality excellence by executing business programs across manufacturing sites, collaborating with cross-functional teams to enhance product standards, manage consumer insights, and drive conti...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Food & Beverages

$145K - $218K *

Transform your career by driving clinical trial success through strategic site engagement and collaboration with key opinion leaders in Neuroscience and Oncology, enhancing patient enrollment and rete...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Optimize patient care by ensuring accurate medication dispensing and compliance. Collaborate with healthcare teams to provide clinical guidance and maintain high standards in a dynamic pharmacy enviro...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.