Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$108K - $147K *

Lead a dynamic team in enhancing member-centered care through effective utilization management. Drive quality improvement, ensure compliance, and foster strategic partnerships to optimize healthcare d...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$200K *

Bring your expertise to a supportive dental practice focused on patient-centered care. Enjoy flexible scheduling, competitive earnings, and the opportunity to build lasting relationships in a thriving...

Today

  •   Less than 5 years exp.  •   Healthcare

$87K *

Empower your career by providing essential physical therapy services, assisting patients in restoring mobility and achieving their goals while collaborating with a dedicated team in a supportive envir...

Today

  •   Less than 5 years exp.  •   Staffing

$87K *

Take ownership of patient care by delivering effective physical therapy services under supervision. Collaborate with healthcare teams to enhance mobility and function, ensuring compliance with regulat...

Today

  •   Less than 5 years exp.  •   Staffing

$100K - $120K *

Transform the future of food safety and quality assurance by leading compliance programs, enhancing product integrity, and fostering a proactive culture. Collaborate across teams to ensure high standa...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$113K - $155K *

Champion quality excellence by executing business programs across manufacturing sites, collaborating with cross-functional teams to enhance product standards, manage consumer insights, and drive conti...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Food & Beverages

$145K - $218K *

Transform your career by driving clinical trial success through strategic site engagement and collaboration with key opinion leaders in Neuroscience and Oncology, enhancing patient enrollment and rete...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Optimize patient care by ensuring accurate medication dispensing and compliance. Collaborate with healthcare teams to provide clinical guidance and maintain high standards in a dynamic pharmacy enviro...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead patient care initiatives by filling prescriptions, counseling patients, and supporting pharmacy operations. Collaborate with healthcare teams to enhance wellness programs and community outreach...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$67K - $111K *

Lead the charge in delivering compassionate, expert behavioral health care across diverse populations, ensuring continuity and support throughout each member's wellness journey while leveraging clinic...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$77K - $202K *

Innovate healthcare payer platforms by analyzing complex issues, guiding teams, and enhancing client experiences. Collaborate on modernization efforts, leveraging Epic software to streamline operation...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Lead a dynamic rehab team, ensuring effective clinical programs and compliance while fostering collaboration and quality care in a supportive environment. Drive initiatives that enhance patient outcom...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $116K *

Lead the charge in enhancing patient care by managing clinic operations, training staff, and fostering community engagement. Join a collaborative environment focused on continuous learning and quality...

Today

  •   Less than 5 years exp.  •   Healthcare

$87K *

Join a team that's dedicated to enhancing patient mobility and function. As a Physical Therapist Assistant, you'll provide essential therapy services, collaborate with healthcare professionals, and co...

Today

  •   Less than 5 years exp.  •   Staffing

$80K - $95K *

Lead the charge in managing site operations and vendor relations, ensuring compliance and efficiency in clinical research projects. Collaborate with teams to streamline processes and enhance training...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Develop high-quality, scientifically accurate content for medical affairs and promotional education. Collaborate with teams to ensure clarity and compliance while translating complex data into engagin...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Advance nursing operations by leading teams to ensure compliance and high standards of care. Drive person-centered practices, enhance team effectiveness, and foster growth while managing administrativ...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Drive nursing operations across Iowa, ensuring compliance and high standards while fostering a compassionate, person-centered care model. Lead and mentor teams to enhance care delivery and operational...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead and optimize nursing operations across Iowa, ensuring compliance and high standards. Inspire teams to deliver exceptional care while managing staffing, budgets, and operational efficiency in a pe...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's dedicated to enhancing resident care through leadership and compassion. Oversee nursing operations, ensure compliance, and inspire staff while driving operational efficiency across...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Shape nursing operations across Iowa by leading teams, ensuring compliance, and fostering a compassionate care environment. Drive efficiency and quality while mentoring staff to enhance resident exper...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the charge in nursing operations across Iowa, ensuring compliance and high standards while fostering a compassionate, person-centered care environment. Inspire and mentor staff to deliver excepti...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead transformative nursing operations across Iowa, ensuring high standards of care and compliance. Inspire teams to deliver compassionate, person-centered care while driving operational efficiency an...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate nursing operations by leading a compassionate team, ensuring regulatory compliance, and fostering a person-centered care model that enhances resident dignity and independence across Iowa's ski...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Champion a culture of compassionate care as you lead nursing operations across Iowa. Drive excellence in clinical standards, mentor staff, and ensure regulatory compliance while enhancing resident exp...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.