Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs offering salaries of $100,000 or more, from leadership positions to specialized roles. Whether you’re targeting a new opportunity in Columbus, Cleveland, Cincinnati, or another Ohio community, find openings that match your experience and career goals.

Find Opportunities Across Ohio

Ohio’s job market spans major metropolitan areas and a wide range of industries. Search roles in cities such as Columbus, Cleveland, and Cincinnati, as well as opportunities throughout the state. Availability varies by employer and location, so explore current listings to see where your skills are in demand.

Explore Professional Roles and Industries

High-paying Ohio openings may include positions in technology, healthcare, finance, manufacturing, sales, and operations. Listings can range from experienced individual-contributor roles to director, vice president, and executive positions. Review each posting for its responsibilities, qualifications, location, and compensation details.

Make Your Ohio Job Search More Focused

Use Ladders to narrow your search by role, location, and other preferences. Tailor your resume to highlight relevant achievements, leadership experience, and measurable results. Check listings regularly and apply to opportunities that align with your qualifications and compensation expectations.

Discover Your Next Career Move

Find vetted professional jobs paying $100,000 or more in Ohio on Ladders. Browse current openings and take the next step toward a role that fits your experience and ambitions.

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$145K - $155K *

Accelerate the evolution of data analytics by leading modernization efforts, optimizing reporting capabilities, and fostering strategic partnerships across functions to drive data-driven decision-maki...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform clinical operations by leading a dedicated team to enhance patient safety and satisfaction through effective oversight, staff development, and quality management in a collaborative healthcar...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Transform budget planning and execution within clinical informatics, leveraging expertise in PPBE and MFR practices. Collaborate with leadership to ensure financial strategies align with healthcare in...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in innovative automotive bumper design, utilizing CATIA V5/V6 to develop concepts, manage projects, and collaborate with teams to meet OEM standards and enhance product quality...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $126K *

Join a team that drives quality improvement initiatives in healthcare, ensuring compliance with regulatory standards. Lead complex projects, assess program effectiveness, and collaborate to enhance he...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Champion a data transformation journey, driving architectural innovation and modernizing technology stacks, while solving complex data issues in a collaborative, high-impact environment with broad cro...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $210K *

Shape the future of oncology partnerships by driving strategy and execution to expand Daymark's network among leading practices focusing on value-based care. Cultivate relationships, close deals, and...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$74K - $87K *

Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$225K - $281K *

Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$147K - $217K *

Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$85K - $100K *

Lead a dedicated nursing team while ensuring high-quality care for residents. Oversee training, staffing, and compliance with regulations to foster a safe and supportive environment, enhancing both re...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Optimize patient care in outpatient neurology by evaluating and managing neurologic disorders. Collaborate with a multidisciplinary team to enhance treatment plans and ensure quality outcomes in a sup...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $110K *

Join a team that's dedicated to supporting disaster recovery efforts. Collaborate with leadership and clients to navigate complex recovery operations, ensuring effective management of multi-billion do...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Elevate patient care through comprehensive assessments and treatment plans, collaborating with a high-performing medical team to ensure optimal health outcomes while adhering to regulatory standards a...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $288K *

Drive excellence in Solutions Delivery by leading client engagements, ensuring timely execution, and fostering strategic partnerships to enhance operational scalability and client satisfaction across...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Take ownership of patient anesthesia care by administering and monitoring anesthesia during surgical procedures, collaborating with healthcare teams, and ensuring optimal patient outcomes through prec...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $300K *

Shape the future of patient care by administering and monitoring anesthesia during surgical procedures while collaborating with medical teams to ensure safety and effectiveness for all patients...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $130K *

Lead the operational flow of perioperative services, driving strategic initiatives, managing resources, and ensuring compliance with regulatory standards for exceptional patient care...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Elevate patient care by leading radiation oncology and imaging services across multiple locations. Drive operational excellence, compliance, and strategic growth while fostering a collaborative enviro...

Today

  •   5 - 7 years exp.  •   Healthcare

$106K - $145K *

Join us to lead the development of innovative software solutions for the healthcare industry, ensuring high-quality standards and security practices while collaborating with global teams to solve comp...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$106K - $145K *

Pioneer innovative software solutions in healthcare, leading development efforts and collaborating with global teams to create high-quality, secure applications using modern technologies and practices...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$174K - $374K *

Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$133K - $183K *

Pioneer AI solutions across enterprise systems, driving innovation in HR, finance, and procurement through cloud engineering. Your expertise will shape the foundational architecture for custom applica...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$93K - $208K *

Drive growth by providing technical and market analysis for renewable energy and infrastructure financing. Assess project risks, conduct power market evaluations, and support investment decisions acro...

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, senior, leadership, and executive roles across fields such as technology, healthcare, finance, manufacturing, sales, and operations. Available positions vary, so check current postings for details.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, and other Ohio communities. Search by location to see current openings near you or in a city where you’d like to work.

  • How can I find Ohio jobs that pay at least $100,000?question toggle

    Browse Ohio listings on Ladders and review each posting’s compensation information, location, and qualifications. Use available search filters to focus on roles that fit your experience and goals.

  • Are all Ohio jobs on Ladders remote or on-site?question toggle

    Work arrangements vary by employer and position. Review each listing for its location and whether it describes the role as on-site, hybrid, or remote.