Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs offering salaries of $100,000 or more, from leadership positions to specialized roles. Whether you’re targeting a new opportunity in Columbus, Cleveland, Cincinnati, or another Ohio community, find openings that match your experience and career goals.

Find Opportunities Across Ohio

Ohio’s job market spans major metropolitan areas and a wide range of industries. Search roles in cities such as Columbus, Cleveland, and Cincinnati, as well as opportunities throughout the state. Availability varies by employer and location, so explore current listings to see where your skills are in demand.

Explore Professional Roles and Industries

High-paying Ohio openings may include positions in technology, healthcare, finance, manufacturing, sales, and operations. Listings can range from experienced individual-contributor roles to director, vice president, and executive positions. Review each posting for its responsibilities, qualifications, location, and compensation details.

Make Your Ohio Job Search More Focused

Use Ladders to narrow your search by role, location, and other preferences. Tailor your resume to highlight relevant achievements, leadership experience, and measurable results. Check listings regularly and apply to opportunities that align with your qualifications and compensation expectations.

Discover Your Next Career Move

Find vetted professional jobs paying $100,000 or more in Ohio on Ladders. Browse current openings and take the next step toward a role that fits your experience and ambitions.

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$103K - $140K *

Engage in advanced cybersecurity incident response, leading investigations and recovery efforts. Collaborate with cross-functional teams to enhance security posture and document findings, ensuring org...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Unlock potential by building and supporting AWS cloud infrastructure for AI/ML and Data Science teams. Collaborate on Kubernetes, Docker, and Terraform to enhance platform operations and troubleshoot...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Accelerate progress at driving strategic M&A initiatives by managing deal execution, from financial modeling to synergy analysis, while collaborating with senior leadership and ensuring organized proc...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $119K *

Empower healthcare practices by providing clinical expertise and education, driving product enhancements, and collaborating with sales teams to optimize customer success and business retention in your...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $119K *

Take ownership of clinical expertise and educational programs to enhance Medline's surgical products. Collaborate with sales and customers to improve practices and identify opportunities for better bu...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $138K *

Engineer operational excellence by leading the Problem Management team, driving post-incident processes, and fostering continuous improvement initiatives to enhance platform stability and customer exp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform numerical capabilities by developing innovative algorithms and solutions, engaging in model building, and collaborating with software teams to enhance product performance and deliver impactf...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$141K - $278K *

Lead the charge in delivering innovative AI solutions by engaging with clients, managing complex projects, and guiding teams through the development of advanced data products and analytics pipelines t...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$141K - $278K *

Champion innovative AI solutions by leading complex data science projects, engaging with clients, and driving technical delivery. Collaborate with teams to design, prototype, and implement advanced an...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$141K - $278K *

Unlock potential by leading AI and Data initiatives, driving client engagement, and delivering innovative solutions. Collaborate with teams to design, prototype, and implement advanced data products w...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Grow your career with a dynamic role that optimizes imaging services, enhances patient experiences, and fosters team development while ensuring operational compliance and excellence in a collaborative...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Ensure data integrity and compliance in clinical trials. Manage EDC development, oversee data cleaning, and liaise with vendors. Lead data management from initiation to close-out while optimizing data...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Unlock potential by leading product development initiatives, collaborating with cross-functional teams to drive innovation, and enhancing market presence through strategic insights and competitive ana...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $235K *

Transform healthcare operations by partnering with client leaders to ensure effective Revenue Integrity during Epic implementations. Leverage your expertise to drive informed decisions and optimize re...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Shape the future of data governance by leading methods and standards across enterprise systems. Collaborate with teams to define quality rules and documentation, ensuring consistency and excellence in...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$87K - $235K *

Explore innovative AI and data science solutions, managing end-to-end projects that drive efficiency and growth. Lead diverse teams, engage stakeholders, and customize analytics models to meet busines...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$87K - $235K *

Empower decision-making by leading AI and Data Science initiatives, managing cross-functional teams, and delivering innovative analytics solutions that drive efficiency and growth for clients across v...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$87K - $235K *

Contribute to innovative AI and Data Science projects, managing teams and driving strategic solutions. Leverage advanced analytics to enhance decision-making and foster client relationships while ensu...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Lead the charge in delivering exceptional care and compliance in our facility. Oversee operations, manage budgets, and foster relationships to create a positive environment for residents and staff whi...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Drive continuous improvement initiatives to enhance quality, reduce costs, and boost productivity. Collaborate with stakeholders to implement process metrics and foster a culture of sustainable change...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Empower clinical research by leading studies in infectious diseases, ensuring scientific integrity and collaboration with stakeholders. Drive trial design, monitor data, and support medical activities...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Empower our mission by ensuring cybersecurity compliance and risk management for the Veterans Health Administration's Enrollment System. Collaborate with stakeholders to maintain security documentatio...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Partner with us to enhance cybersecurity by monitoring threats, analyzing incidents, and implementing defense strategies. Join a dynamic team dedicated to protecting our enterprise network through pro...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$54K - $145K *

Transform your career by leading financial planning and analysis efforts, driving strategic initiatives, and collaborating with stakeholders to align financial goals with business objectives while ens...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$79K - $142K *

Elevate data-driven decision-making by transforming HR data into strategic insights. Leverage analytical skills and tools to enhance workforce performance and support HR initiatives, ensuring data acc...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, senior, leadership, and executive roles across fields such as technology, healthcare, finance, manufacturing, sales, and operations. Available positions vary, so check current postings for details.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, and other Ohio communities. Search by location to see current openings near you or in a city where you’d like to work.

  • How can I find Ohio jobs that pay at least $100,000?question toggle

    Browse Ohio listings on Ladders and review each posting’s compensation information, location, and qualifications. Use available search filters to focus on roles that fit your experience and goals.

  • Are all Ohio jobs on Ladders remote or on-site?question toggle

    Work arrangements vary by employer and position. Review each listing for its location and whether it describes the role as on-site, hybrid, or remote.