Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$104K - $143K *
Shape the future of pharmacy software by leading product strategy, managing cross-functional teams, and driving improvements in patient outcomes and business results through innovative product managem...
Today
GCG Operating Office - Analyst
$80K - $95K *
Champion operational excellence by driving financial analysis and strategic planning. Collaborate with senior leaders to enhance sales management and optimize performance across the Global Client Grou...
3 weeks ago
$180K - $220K *
Join our team to provide comprehensive dermatological care, collaborating with medical staff to enhance patient outcomes. You'll manage both inpatient and outpatient cases, ensuring effective communic...
3 weeks ago
$74K - $87K *
Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...
3 weeks ago
System Vice President State Government Affairs
$160K - $200K *
Lead strategic state government affairs initiatives, shaping policy and advocacy efforts. Collaborate with diverse stakeholders to align organizational priorities with legislative agendas, ensuring im...
1 week ago
Associate Medical Director, Clinical Research
$225K - $281K *
Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...
3 weeks ago
Associate Medical Director, Clinical Research
$225K - $281K *
Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...
3 weeks ago
Program Manager, Client Services, Clinical Trial Support
$88K - $105K *
Lead the charge in managing client relationships and program performance, ensuring timely delivery of medications. Oversee budgets, facilitate communication between stakeholders, and drive successful...
6 days ago
Lead Engineer Stability Analysis-2
$85K - $164K *
Join a team that's dedicated to enhancing reactor safety through advanced thermal-hydraulic stability analyses. Collaborate across disciplines to support operational needs and fuel-related projects fo...
5 days ago
$147K - $217K *
Join a team that's redefining analytics in life sciences. Lead innovative measurement strategies, mentor talent, and drive impactful client solutions while navigating complex data ecosystems and foste...
2 weeks ago
$147K - $217K *
Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...
2 weeks ago
$95K - $115K *
Drive patient care excellence as a Physician Assistant or Nurse Practitioner, collaborating with a multidisciplinary team to provide comprehensive medical services in both inpatient and outpatient set...
2 weeks ago
Director of Business Development
$110K - $130K *
Lead the charge in expanding strategic partnerships and driving growth initiatives with autonomy. Collaborate with leadership to assess market trends, enhance client relationships, and achieve sales t...
3 weeks ago
$70K - $110K *
Join a team that's dedicated to supporting disaster recovery efforts. Collaborate with leadership and clients to navigate complex recovery operations, ensuring effective management of multi-billion do...
4 days ago
$174K - $374K *
Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...
Reposted 1 week ago
Clinical Sales Training Specialist, Structural Heart
$102K - $182K *
Lead the design and delivery of innovative clinical sales training programs for Structural Heart, enhancing sales team effectiveness and product knowledge through strategic curriculum development and...
Reposted 2 days ago
Registered Nurse (RN) - Levine Children's Hospital - Pediatric ED
$79K - $118K *
Engage your nursing expertise in a dynamic Pediatric Emergency Department, providing critical care to children in a fast-paced, high-acuity environment. Collaborate with a dedicated team to ensure exc...
Reposted 2 days ago
Nurse Manager- Emergency Department
$85K - $100K *
Lead the charge in delivering exceptional patient care by providing clinical and administrative leadership in the Emergency Department. Focus on team development, operational efficiency, and fostering...
2 weeks ago
Director Performance Excellence
$78K - $125K *
Lead large-scale performance improvement initiatives, driving operational excellence and strategic project opportunities across the enterprise. Collaborate with stakeholders to enhance service deliver...
Reposted 2 days ago
Power Market and Technical Diligence Analyst
$93K - $208K *
Transform energy financing by conducting in-depth market analysis and technical diligence for renewable and conventional power projects, ensuring informed investment decisions and optimal asset manage...
1 week ago
Area Medical Director - Oncology
$250K - $360K *
Lead the charge in advancing oncology diagnostics by engaging community oncologists, driving medical strategy, and executing initiatives across a defined region in this impactful, field-based leadersh...
3 weeks ago
R2600885 Technology/Cyber Testing and Monitoring - Senior Risk Analyst
$85K - $150K *
Execute technology risk assessments and control testing while collaborating with cross-functional teams to enhance cybersecurity practices and mitigate emerging risks. Drive continuous improvement ini...
4 days ago
$80K - $95K *
Shape the future of software solutions by collaborating with cross-functional teams to gather requirements, enhance customer satisfaction, and ensure quality delivery of features aligned with the prod...
3 weeks ago
$150K - $180K *
Unlock potential by leading actuarial data analyses and modeling to support cross-functional teams. Collaborate with senior leaders to build tools for trend projections and risk assessments, driving i...
6 days ago
$150K - $180K *
Pioneer strategic leadership in Multi-Party Project Coordination & Liability Management, driving business growth, client relationships, and team development while overseeing complex environmental prog...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.