Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Manager, Health Informatics (Pacific Southwest)
$152K - $253K *
Elevate healthcare delivery by leveraging health information technology to enhance patient care and operational efficiency. Collaborate with health systems and cross-functional teams to align technolo...
Today
Senior Software Engineer (New Health Care Company)
$106K - $145K *
Join us to lead the development of innovative software solutions for the healthcare industry, ensuring high-quality standards and security practices while collaborating with global teams to solve comp...
2 days ago
Senior Software Engineer (New Health Care Company)
$106K - $145K *
Pioneer innovative software solutions in healthcare, leading development efforts and collaborating with global teams to create high-quality, secure applications using modern technologies and practices...
2 days ago
$174K - $374K *
Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...
Reposted 1 week ago
Clinical Sales Training Specialist, Structural Heart
$102K - $182K *
Lead the design and delivery of innovative clinical sales training programs for Structural Heart, enhancing sales team effectiveness and product knowledge through strategic curriculum development and...
Reposted yesterday
Registered Nurse (RN) - Levine Children's Hospital - Pediatric ED
$79K - $118K *
Engage your nursing expertise in a dynamic Pediatric Emergency Department, providing critical care to children in a fast-paced, high-acuity environment. Collaborate with a dedicated team to ensure exc...
Reposted 2 days ago
Nurse Manager- Emergency Department
$85K - $100K *
Lead the charge in delivering exceptional patient care by providing clinical and administrative leadership in the Emergency Department. Focus on team development, operational efficiency, and fostering...
2 weeks ago
Director Performance Excellence
$78K - $125K *
Lead large-scale performance improvement initiatives, driving operational excellence and strategic project opportunities across the enterprise. Collaborate with stakeholders to enhance service deliver...
Reposted 2 days ago
SIGINT Analyst / Target Analyst Reporter
$78K - $163K *
Empower operational excellence by analyzing multi-source intelligence to produce actionable insights. Collaborate with military and intelligence communities to enhance target development, support miss...
Reposted 1 week ago
Power Market and Technical Diligence Analyst
$93K - $208K *
Transform energy financing by conducting in-depth market analysis and technical diligence for renewable and conventional power projects, ensuring informed investment decisions and optimal asset manage...
1 week ago
$175K *
Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...
1 week ago
Area Medical Director - Oncology
$250K - $360K *
Lead the charge in advancing oncology diagnostics by engaging community oncologists, driving medical strategy, and executing initiatives across a defined region in this impactful, field-based leadersh...
3 weeks ago
Chief Nursing Officer / Director of Nursing RN
$90K - $110K *
Pioneer exceptional care by leading nursing teams, ensuring quality health services, and coordinating resident care in a dynamic healthcare environment. Drive improvements and uphold standards while f...
6 days ago
R2600885 Technology/Cyber Testing and Monitoring - Senior Risk Analyst
$85K - $150K *
Execute technology risk assessments and control testing while collaborating with cross-functional teams to enhance cybersecurity practices and mitigate emerging risks. Drive continuous improvement ini...
4 days ago
$160K - $200K *
Unlock potential by leading managed care strategies across a complex health system. Drive payer negotiations, optimize contract performance, and enhance population health initiatives while collaborati...
1 week ago
Program Specialist, Care Management
$74K - $119K *
Transform healthcare delivery by coordinating strategic programs that enhance clinical and operational excellence. Collaborate with diverse teams to implement innovative solutions, ensuring compliance...
4 days ago
$80K - $95K *
Shape the future of software solutions by collaborating with cross-functional teams to gather requirements, enhance customer satisfaction, and ensure quality delivery of features aligned with the prod...
3 weeks ago
$150K - $180K *
Unlock potential by leading actuarial data analyses and modeling to support cross-functional teams. Collaborate with senior leaders to build tools for trend projections and risk assessments, driving i...
6 days ago
$150K - $180K *
Pioneer strategic leadership in Multi-Party Project Coordination & Liability Management, driving business growth, client relationships, and team development while overseeing complex environmental prog...
3 weeks ago
Senior Enterprise Solution Architect
$102K - $164K *
Join a team that's shaping the future of enterprise solutions by leading innovative design and implementation of scalable architectures. Collaborate with stakeholders, define strategy, and ensure adhe...
Reposted 3 weeks ago
Sr. Manager of Medicare Compliance
$110K - $130K *
Champion compliance excellence by leading innovative technology integration and regulatory strategies across Medicare Advantage and Part D channels, ensuring seamless operations and enhanced agent eff...
1 week ago
Lead Engineer Stability Analysis-1
$85K - $164K *
Join a team that's dedicated to enhancing reactor safety through advanced thermal-hydraulic stability analyses, collaborating across disciplines to support operational needs and innovative fuel design...
4 days ago
Senior Director, Project Management, Health & Life Sciences Market Research (Remote, US-based only)
$120K - $135K *
Shape the future of project management in global health by leading teams, ensuring timely delivery, and driving operational excellence across multiple projects while aligning with client and business...
3 days ago
$114K - $171K *
Join a team that's focused on optimizing patient flows and operationalizing new environments. Collaborate across multidisciplinary teams to enhance service-line improvements and ensure effective plann...
5 days ago
$91K - $137K *
Drive your career forward by leading patient flow and supervising advanced procedures in a dynamic medical imaging environment. Collaborate with a skilled team to enhance departmental efficiency and e...
2 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.