Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Sys VP Clinical and Industry Trials
$180K - $220K *
Empower innovation in clinical trials by developing strategies, overseeing operations, and cultivating partnerships. Drive excellence in research, enhance compliance, and manage a high-performing team...
Reposted 3 days ago
Senior Cyber Intelligence Analyst
$110K - $130K *
Transform the approach to threat intelligence and detection engineering by leading comprehensive analysis, driving proactive vulnerability prioritization, and mentoring a talented team of analysts to...
3 weeks ago
Lead Enterprise Salesforce Architect
$142K - $195K *
Transform client experiences by leading digital strategy and architecture initiatives. Collaborate with cross-functional teams to design scalable solutions, enhance data integration, and drive measura...
2 weeks ago
Assistant General Counsel, Healthcare Compliance and Investigations
$145K - $405K *
Provide expert legal guidance on healthcare compliance, internal investigations, and anti-bribery regulations. Collaborate with cross-functional teams to ensure effective compliance programs and mitig...
2 weeks ago
Strategic Account Associate, Medical Communications
$70K - $105K *
Elevate client relationships by managing strategic accounts, coordinating project execution, and driving client engagement. Contribute to financial management and proactive growth opportunities while...
1 month ago
$110K - $130K *
Drive impactful solutions as you lead integration efforts, enhancing user experiences through collaboration and innovation while managing multiple complex projects and mentoring junior engineers...
3 weeks ago
$140K - $185K *
Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...
Reposted 2 weeks ago
Senior Specialist, Data Engineering and Analytics
$117K - $184K *
Lead the charge in enhancing data engineering and analytics to optimize technical operations and business performance. Collaborate across teams to deliver scalable solutions that improve data access a...
1 week ago
Associate, Brand Strategy and Activation
$71K - $97K *
Drive brand strategy and activation efforts by translating insights into impactful marketing initiatives. Collaborate with cross-functional teams to enhance brand awareness and customer engagement acr...
Today
$225K - $265K *
Transform healthcare interoperability by leading product strategy and market growth. Leverage deep industry insights to enhance payer-provider collaboration, drive operational excellence, and oversee...
3 weeks ago
Cardiothoracic Physician's Assistant
$100K - $120K *
Support surgical excellence by collaborating in a leading cardiothoracic practice, performing first assists and providing comprehensive patient care in a dynamic team environment focused on advanced c...
3 weeks ago
Senior Business Development Executive Clinical Services
$101K - $197K *
Lead the development and execution of strategic sales initiatives to enhance market share and client relationships within designated therapeutic areas, ensuring alignment with organizational goals and...
Reposted 1 week ago
Associate General Counsel, Contracts
$129K - $162K *
Empower healthcare transformation by providing legal support in payor contracting. Collaborate with cross-functional teams to negotiate, draft, and manage contracts, ensuring compliance with regulator...
Reposted 1 month ago
Senior Project Manager - Oncology
$128K - $254K *
Drive successful clinical trials by coordinating project management activities, ensuring quality deliverables, and collaborating with multidisciplinary teams to meet client expectations in a dynamic e...
1 week ago
IOM Technologist-Traveler East Coast
$80K - $95K *
Champion patient safety by monitoring neuromuscular function during surgeries. Collaborate with surgical teams to ensure optimal outcomes through real-time data analysis and communication, making a si...
1 week ago
$100K - $120K *
Join a team that's dedicated to ensuring financial integrity and compliance. In this hands-on role, you'll manage revenue recognition and accounting processes, collaborating across departments to supp...
1 week ago
Clinical Applications Specialist, Invasive Cardiology
$92K - $138K *
Elevate your career by delivering expert clinical education and training. Drive customer success through hands-on support and relationship building, optimizing product adoption and enhancing patient c...
3 days ago
Clinical Applications Specialist, Invasive Cardiology
$92K - $138K *
Help us enhance clinical education by delivering expert training and support to healthcare professionals. Drive product adoption and optimize user competencies while fostering strong relationships wit...
1 week ago
$95K - $115K *
Drive the development and validation of analytical methods for drug formulation. Manage projects in a GMP laboratory, support stability testing, mentor junior scientists, and collaborate with cross-fu...
3 weeks ago
MedCenter Air Critical Care Transport Respiratory Therapist
$68K - $103K *
Reimagine critical care transport by providing expert patient care during transport. Collaborate with a dedicated team to ensure safety and efficiency while utilizing advanced medical procedures and t...
4 days ago
$95K - $115K *
Advance your career by supporting financial reporting, analysis, and forecasting processes. Collaborate with leadership and cross-functional teams to enhance reporting efficiency and drive insights th...
Reposted 2 days ago
$90K - $115K *
Lead the execution and optimization of email and SMS marketing channels, enhancing performance and compliance. Own end-to-end processes, from creative testing to analytics, while collaborating cross-f...
3 weeks ago
$200K - $245K *
Join a team that's dedicated to providing expert employment counsel across a global workforce. You'll partner with business leaders to navigate complex employment issues, ensuring sound legal advice t...
Reposted 2 weeks ago
Senior Software Engineer II - Agentic SDLC
$170K - $185K *
Champion innovative software solutions by leading complex projects, mentoring engineers, and driving technical excellence across teams. Collaborate on strategic initiatives to enhance reliability and...
3 days ago
$80K - $110K *
Discover your potential by supporting data-driven decision-making as you develop and implement advanced statistical and machine learning models. Collaborate with stakeholders and enhance your skills i...
Reposted 2 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.