Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Healthcare Analyst Jobs in North Carolina

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$77K - $105K *

Join a dynamic team to analyze healthcare claims data, identify fraud trends, and support the Healthcare Fraud Prevention Partnership. Leverage your expertise to drive strategic outcomes and enhance c...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $220K *

Transform healthcare as you join a collaborative team dedicated to providing quality family medicine in a picturesque mountainous region. Embrace an outpatient-focused role with supportive staff in a...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading country strategy and feasibility assessments, overseeing site selection, and managing cross-functional partnerships to optimize clinical trial success across global markets...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Shape the future of clinical trials by leading country selection and feasibility assessments, ensuring optimal site identification, and driving data-driven recommendations for global studies across di...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower global clinical operations by leading country selection and feasibility assessments, ensuring data-driven site recommendations, and managing cross-functional partnerships to optimize enrollmen...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping global clinical strategies by leading feasibility assessments, site selection, and data analysis to optimize enrollment and ensure successful trial execution across diverse...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$129K - $177K *

Elevate your career by leading the design and development of AI-driven automation solutions. Collaborate with cross-functional teams to enhance data governance processes through innovative engineering...

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $150K *

Join a team that's dedicated to enhancing clinical support through technical expertise and customer training. Drive product demonstrations and ensure customer satisfaction while collaborating with sal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$77K - $106K *

Advance your career by providing personalized home health nursing care. Collaborate with a dedicated team to develop care plans, monitor patient progress, and educate families, all while making a mean...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by overseeing Workday System infrastructure, providing end-to-end administration and ensuring data integrity. Collaborate with HR, IT, and vendors to enhance systems and support workf...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$74K - $85K *

Lead the planning and execution of diverse research projects, ensuring alignment with organizational goals. Collaborate with stakeholders to manage timelines, deliverables, and budgets while fostering...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $161K *

Advance your career by coordinating clinical trial budgets and coverage analyses. Collaborate with stakeholders to ensure compliance and cost efficiency while mentoring junior staff and enhancing admi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$75K - $110K *

Unlock advanced analytics capabilities by leading data science initiatives that drive informed decision-making and operational efficiency in a regulated environment. Collaborate with stakeholders to d...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Finance & Insurance

$79K - $118K *

Join a dynamic medical-surgical unit providing comprehensive care for diverse diagnoses. Collaborate with multidisciplinary teams to enhance patient outcomes while engaging in professional governance...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Drive the development of LLM-based agents, ensuring robust production systems, effective evaluation, and seamless integration with company data while maintaining security and operational excellence ac...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Shape patient care by joining a thriving urology practice as an advanced practice provider. Operate autonomously in a supportive environment, seeing patients and performing essential office procedures...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$134K - $176K *

Join a team that's shaping the future of Product Lifecycle Management by driving data-driven insights and operational efficiency. Collaborate with cross-functional leaders to enhance strategies and fo...

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Drive the future of AI & Analytics by leading client relationships, providing strategic guidance, and delivering innovative solutions. Leverage your expertise to enhance service delivery and ensure al...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$86K - $138K *

Unlock innovative healthcare solutions by leading product strategy and lifecycle management for clinical programs. Collaborate across teams to enhance member experiences and drive business value while...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $205K *

Join a dynamic team to lead AI agent deployments in healthcare. Leverage your software engineering expertise and client-facing skills to drive technical delivery, influence product development, and en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $107K *

Drive financial integrity by managing complex accounting tasks, preparing reports, and influencing departmental strategy. Collaborate with teams to ensure compliance and accuracy while providing valua...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by managing coding operations, ensuring accuracy and compliance across healthcare settings. Lead educational initiatives for staff, optimize workflows, and drive improvements in co...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$136K - $187K *

Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$116K - $143K *

Champion data integrity by ensuring accuracy and governance, enabling impactful business analytics solutions and driving consistent data quality across the organization through mastery of data process...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$79K - $118K *

Join a team that's dedicated to providing exceptional oncology care. As a vital RN, you'll coordinate comprehensive patient care in a fast-paced environment, ensuring safety and therapeutic support fo...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.