Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Principal, Data Governance Platforms
$149K - $224K *
Shape the future of data governance by leading the design and implementation of enterprise platforms that ensure data integrity, quality, and compliance across the organization, while collaborating wi...
2 weeks ago
Clinical Informatics Specialist
$102K - $133K *
Unlock potential by optimizing clinical systems and driving informatics initiatives. This role combines strategy with hands-on support across EHR applications, fostering collaboration to enhance workf...
Reposted 2 weeks ago
$148K - $256K *
Shape the future of data engineering by architecting scalable, cloud-native data platforms on Azure and Databricks. Influence the organization’s data practices to leverage AI-driven insights, driving...
Reposted 1 week ago
$112K - $169K *
Help us enhance healthcare integration by designing and implementing HL7 interfaces for Perinatal Systems. Collaborate with clients and vendors to streamline hospital IT systems, ensuring efficient da...
3 weeks ago
Manager, Business Development, National Center for Clinical Trials (NCCT)
$114K - $171K *
Join a team that's driving growth in clinical trials by identifying and securing partnerships. Collaborate with cross-functional leaders to enhance visibility and expand opportunities, ensuring seamle...
3 weeks ago
Mgr, Business Analysis, Workforce Initiatives, Data & Analytics
$66K - $145K *
Drive impactful workforce analytics and business intelligence initiatives by transforming data into strategic insights that enhance talent and operational outcomes. Collaborate across departments to f...
Reposted 1 week ago
Medical Review Analyst - Medicare
$66K - $106K *
Lead the charge in conducting medical record reviews and applying clinical judgment to ensure accurate claim payment decisions while supporting fraud investigations and compliance efforts...
2 weeks ago
$88K - $105K *
Manage operations of the K9 Oncology unit, ensuring high-quality nursing care through effective resource allocation and compliance with standards, while fostering research and promoting professional d...
Reposted yesterday
Senior Analyst, Client Insights
$124K - $145K *
Join our Client Insights team to transform data into actionable insights that drive sales and merchant retention. Collaborate across analytics, product, and strategy to enhance AI-driven solutions for...
1 week ago
Healthcare Enterprise Sales Director
$368K - $500K+*
Drive your career with a dynamic team as you lead sales efforts in the healthcare sector, managing a skilled group of Account Managers to achieve revenue targets and foster business growth in a fast-p...
4 days ago
Nurse Practitioner, Health Center Manager
$90K - $110K *
Champion efficient health center operations while delivering quality patient care. Oversee staff management, process improvements, and compliance initiatives to enhance health outcomes and ensure a se...
1 week ago
Epidemiology Research Associate II, Injury Surveillance & Analytics
$89K - $223K *
Champion data-driven insights in a dynamic team, enhancing injury surveillance and analytics through innovative research and automation. Collaborate on impactful projects that shape decision-making an...
1 week ago
Care Path Educator, Tzield Raleigh, NC
$125K - $180K *
Analyze and educate on T1D screening best practices, driving operational efficiency in healthcare settings. Collaborate with stakeholders to enhance patient pathways and ensure effective care coordina...
2 weeks ago
Integration Analyst Engineer (Remote)
$115K - $125K *
Empower your career by driving the integration and migration of data for a vital financial management system. Collaborate with experts to enhance system reliability and operational efficiency in a ful...
2 weeks ago
$85K - $100K *
Transform patient care by collaborating with a multidisciplinary team to develop and implement effective rehabilitation plans, ensuring optimal functional outcomes and independence for diverse patient...
2 weeks ago
Medicare Risk Adjustment Compliance Auditor (CPC, CCS, or CCS-P Required) (Remote)
$64K - $96K *
Engage in comprehensive risk adjustment audits and compliance reviews, ensuring accurate data submission to CMS. Collaborate with coding teams and management to uphold regulatory standards and improve...
Reposted 6 days ago
Senior Financial and Budget Analyst (Remote)
$120K - $130K *
Elevate financial management and strategic planning efforts by providing expert analysis, guidance, and support for budget formulation and execution within a dynamic team focused on mission delivery f...
1 week ago
Registered Nurse (RN)-Emergency Department
$79K - $118K *
Join a team that's dedicated to delivering high-quality, compassionate care in a dynamic Emergency Department. Collaborate with diverse healthcare professionals to shape workflows and enhance patient...
Reposted 3 days ago
Product Analyst - Anatomic Pathology (Laboratory/LIS Specialist)
$90K - $120K *
Optimize product development by leveraging your Anatomic Pathology expertise to analyze requirements, document features, and drive engineering efforts, ensuring timely and compliant software releases...
2 weeks ago
Senior Coding Compliance Auditor - Inpatient
$76K - $131K *
Elevate healthcare compliance by leading detailed coding audits, mentoring auditors, and implementing action plans. Drive innovation and ensure adherence to standards while fostering a culture of cont...
2 weeks ago
Senior HCM Analytics & BI Developer
$105K - $231K *
Optimize enterprise analytics solutions to provide real-time insights and reporting for federal HR stakeholders, driving strategic decision-making and compliance in a fast-paced modernization initiati...
Reposted 1 week ago
$74K - $107K *
Drive comprehensive patient care as an RN Care Manager, coordinating assessments, care plans, and transitions in a collaborative environment to enhance patient outcomes and support their healthcare jo...
1 week ago
$95K - $115K *
Lead the charge in enhancing clinical data quality and interoperability. Collaborate with clinical evaluators and product teams to drive improvements in healthcare data management and support quality...
2 days ago
Assistant Director, Global Service Delivery
$100K - $120K *
Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...
3 days ago
Healthcare Provider Finance, Supply Chain, HCM Consultant - Senior Manager
$124K - $280K *
Drive transformation in healthcare by leading finance, supply chain, and HCM consulting projects. As a Senior Manager, you'll enhance operational efficiency and guide technology adoption, ensuring ali...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.