Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Senior Manager, Stop-Loss Risk and Proposals
$110K - $130K *
Take ownership of the sales process for self-funded stop-loss cases, evaluating risk, managing proposals, and collaborating with underwriters to enhance case preparation and market success...
1 week ago
$110K - $130K *
Join a team that's leading Medicaid programs and initiatives, driving operational excellence and policy implementation while managing multidisciplinary teams and enhancing organizational performance a...
2 weeks ago
Business Analyst/Business Process Modeler (Remote)
$85K - $95K *
Unlock potential by leading business analysis to transform processes into actionable requirements for a major financial management system. Collaborate with stakeholders to enhance workflows and ensure...
2 weeks ago
$90K - $110K *
Innovate data solutions by developing complex reports and analyses to support senior management and client needs. Collaborate with teams to enhance data literacy and provide technical guidance across...
3 days ago
Senior Decision Intelligence Engineer
$106K - $147K *
Champion the development of ML pipelines, ensuring scalable, reliable decision-making systems that optimize member outcomes while collaborating with cross-functional teams to enhance platform performa...
3 weeks ago
Vice President - Enterprise Applications
$163K - $218K *
Lead the strategy and delivery of enterprise applications, optimizing technology platforms to enhance clinical care and business operations. Collaborate with cross-functional teams to drive improvemen...
1 week ago
$80K - $95K *
Empower growth by developing strategic relationships with biotech and pharma clients. Drive market awareness and increase RFPs through collaboration with the business development team, leveraging your...
3 days ago
$120K - $160K *
Analyze complex data and drive solutions as a Business Analyst in the public sector. Leverage your expertise in pension systems to identify issues and enhance processes, ensuring effective communicati...
Reposted today
$68K - $105K *
Champion the implementation and support of Epic Beaker applications, ensuring effective system design, user experience, and problem resolution while managing projects and enhancing end-user engagement...
2 weeks ago
$89K *
Shape the future of data architecture and AI strategy in healthcare. Lead the design and governance of enterprise data systems while ensuring AI readiness and data integrity. Drive innovation and acco...
2 weeks ago
Enterprise Architect - Emerging Analytics
$134K - $209K *
Join a team that's redefining data architecture and analytics. Leverage your expertise to drive cloud adoption, modernize data platforms, and influence strategic initiatives that empower data-driven d...
2 weeks ago
$120K - $145K *
Drive the transformation of AI solutions by developing, deploying, and optimizing machine learning models. Collaborate with stakeholders to create innovative applications that enhance patient care whi...
Today
$78K - $156K *
Join a team that's dedicated to enhancing business systems through design, configuration, and support. As a Senior Application Analyst, you'll lead improvements, mentor junior analysts, and ensure sea...
1 week ago
$135K *
Lead and manage healthcare operations within a facility, ensuring compliance with policies and improving efficiency. Collaborate with staff and agencies to meet healthcare needs while overseeing budge...
6 days ago
$79K - $118K *
Lead care management initiatives by collaborating with patients, families, and multidisciplinary teams to ensure timely, effective healthcare delivery while addressing barriers to care and enhancing p...
2 weeks ago
$79K - $118K *
Join a team that's committed to enhancing patient care through collaboration, effective communication, and care coordination. Leverage your clinical expertise to support patients and families in navig...
Reposted 3 weeks ago
$111K - $147K *
Unlock potential by bridging business vision and execution. Lead strategic analysis, synthesize complex data, and drive multi-functional collaboration to enhance digital customer experiences and solve...
4 days ago
$73K - $110K *
Join a dedicated team as a Registered Nurse, providing exceptional care in Orthopedic Services. Leverage your nursing expertise in a supportive environment focused on service excellence and profession...
Reposted 1 week ago
Business Insights Analyst, Remote US
$80K - $95K *
Grow your career with a dynamic role that drives actionable insights across e-commerce and service delivery. Collaborate with stakeholders to analyze data, build impactful reports, and enhance busines...
6 days ago
Principal, Data Governance Platforms
$149K - $224K *
Shape the future of data governance by leading the design and implementation of enterprise platforms that ensure data integrity, quality, and compliance across the organization, while collaborating wi...
2 weeks ago
Clinical Informatics Specialist
$102K - $133K *
Unlock potential by optimizing clinical systems and driving informatics initiatives. This role combines strategy with hands-on support across EHR applications, fostering collaboration to enhance workf...
Reposted 2 weeks ago
$148K - $256K *
Shape the future of data engineering by architecting scalable, cloud-native data platforms on Azure and Databricks. Influence the organization’s data practices to leverage AI-driven insights, driving...
Reposted 1 week ago
$112K - $169K *
Help us enhance healthcare integration by designing and implementing HL7 interfaces for Perinatal Systems. Collaborate with clients and vendors to streamline hospital IT systems, ensuring efficient da...
3 weeks ago
Manager, Business Development, National Center for Clinical Trials (NCCT)
$114K - $171K *
Join a team that's driving growth in clinical trials by identifying and securing partnerships. Collaborate with cross-functional leaders to enhance visibility and expand opportunities, ensuring seamle...
3 weeks ago
Mgr, Business Analysis, Workforce Initiatives, Data & Analytics
$66K - $145K *
Drive impactful workforce analytics and business intelligence initiatives by transforming data into strategic insights that enhance talent and operational outcomes. Collaborate across departments to f...
Reposted 1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.